scholarly journals Cognition in children with neurofibromatosis type 1: data from a population-based study

2015 ◽  
Vol 57 (7) ◽  
pp. 645-651 ◽  
Author(s):  
Annukka Lehtonen ◽  
Shruti Garg ◽  
Stephen A Roberts ◽  
Dorothy Trump ◽  
D Gareth Evans ◽  
...  
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Population Based ◽  
Population Based Study

scholarly journals Autism and other psychiatric comorbidity in neurofibromatosis type 1: evidence from a population-based study

2012 ◽  
Vol 55 (2) ◽  
pp. 139-145 ◽  
Author(s):  
SHRUTI GARG ◽  
ANNUKKA LEHTONEN ◽  
SUSAN M HUSON ◽  
RICHARD EMSLEY ◽  
DOROTHY TRUMP ◽  
...  
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Psychiatric Comorbidity ◽  
Neurofibromatosis Type ◽  
Population Based ◽  
Population Based Study

Neurofibromatosis Type 1: A Population-Based Study

2019 ◽  
Vol 56 (4) ◽  
pp. 243-247
Author(s):  
Bashar M. Bata ◽  
David O. Hodge ◽  
Brian G. Mohney
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Population Based ◽  
Population Based Study

Neurofibromatosis type 1 and pregnancy complications: a population-based study

2013 ◽  
Vol 209 (1) ◽  
pp. 46.e1-46.e8 ◽  
Author(s):  
Anna R. Terry ◽  
Fred G. Barker ◽  
Lisa Leffert ◽  
Brian T. Bateman ◽  
Irene Souter ◽  
...  
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Pregnancy Complications ◽  
Neurofibromatosis Type ◽  
Population Based ◽  
Population Based Study

scholarly journals Pediatric malignancies in neurofibromatosis type 1: A population‐based cohort study

2019 ◽  
Vol 145 (11) ◽  
pp. 2926-2932 ◽  
Author(s):  
Sirkku Peltonen ◽  
Roope A. Kallionpää ◽  
Matti Rantanen ◽  
Elina Uusitalo ◽  
Päivi M. Lähteenmäki ◽  
...  
Keyword(s):  
Cohort Study ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Population Based ◽  
Pediatric Malignancies

Distinctive Cancer Associations in Patients With Neurofibromatosis Type 1

2016 ◽  
Vol 34 (17) ◽  
pp. 1978-1986 ◽  
Author(s):  
Elina Uusitalo ◽  
Matti Rantanen ◽  
Roope A. Kallionpää ◽  
Minna Pöyhönen ◽  
Jussi Leppävirta ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Population Based ◽  
Cancer Type ◽  
Clinical Practices ◽  
Patients With Cancer ◽  
Peripheral Nerve Sheath Tumors ◽  
Risk Of Cancer

Purpose The current study was designed to determine the risk of cancer in patients with neurofibromatosis type 1 (NF1) by cancer type, age, and sex with unprecedented accuracy to be achieved by combining two total population–based registers. Patients and Methods A population-based series of patients with NF1 (N = 1,404; 19,076 person-years) was linked to incident cancers recorded in the Finnish Cancer Registry and deaths recorded in the national Population Register Centre between 1987 and 2012. Standardized incidence ratios (SIRs) and standardized mortality ratios (SMRs) were calculated for selected cancer types. Survival of the patients with cancer with and without NF1 was compared. Results In malignant peripheral nerve sheath tumors and CNS tumors, the cancers traditionally associated with NF1, we observed SIRs of 2,056 (95% CI, 1,561 to 2,658), and 37.5 (95% CI, 30.2 to 46.0), respectively, and SMRs of 2,301 (95% CI, 1,652 to 3,122) and 30.2 (95% CI, 19.1 to 45.2), respectively. We found an unequivocally increased risk for breast cancer. In particular, SIR was 11.1 (95% CI, 5.56 to 19.5) for breast cancer in women with NF1 age < 40 years; the overall SMR for breast cancer was 5.20 (95% CI, 2.38 to 9.88). Particularly high overall SIRs were observed in patients with NF1 age < 15 years: women, 87.6 (95% CI, 58.6 to 125); men, 45.6 (95% CI, 28.4 to 68.5). An estimated lifetime cancer risk for patients with NF1 was 59.6%. The 5-year survival of patients with cancer and NF1, excluding nervous tissue cancers, was worse than that of comparable patients with cancers without NF1 (54.0% v 67.5%; P = .01). Conclusion Our results emphasize the general cancer proclivity of patients with NF1. These findings should translate to clinical practices to determine clinical interventions and focused follow-up of patients with NF1.

Social information processing of children with Neurofibromatosis Type 1

2008 ◽  
Author(s):  
Jonathan M. Kurss ◽  
Anna E. Craig ◽  
Jennifer Reiter-Purtill ◽  
Kathryn Vannatta ◽  
Cynthia Gerhardt
Keyword(s):  
Information Processing ◽  
Neurofibromatosis Type 1 ◽  
Social Information Processing ◽  
Social Information ◽  
Neurofibromatosis Type

Lovastatin improves impaired LTP-like plasticity in patients with Neurofibromatosis Type 1

2011 ◽  
Vol 42 (01) ◽  
Author(s):  
F. Mainberger ◽  
N. Jung ◽  
M. Zenker ◽  
I. Delvendahl ◽  
U. Wahlländer ◽  
...  
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type
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