scholarly journals Synthetic embryology: Early mammalian embryo modeling systems from cell cultures

2021 ◽  
Vol 63 (2) ◽  
pp. 116-126 ◽  
Author(s):  
Kiichiro Tomoda ◽  
Cody Kime
Development ◽  
2020 ◽  
Vol 147 (14) ◽  
pp. dev183079 ◽  
Author(s):  
Berenika Płusa ◽  
Anna Piliszek

ABSTRACTPre-implantation mammalian development unites extreme plasticity with a robust outcome: the formation of a blastocyst, an organised multi-layered structure ready for implantation. The process of blastocyst formation is one of the best-known examples of self-organisation. The first three cell lineages in mammalian development specify and arrange themselves during the morphogenic process based on cell-cell interactions. Despite decades of research, the unifying principles driving early mammalian development are still not fully defined. Here, we discuss the role of physical forces, and molecular and cellular mechanisms, in driving self-organisation and lineage formation that are shared between eutherian mammals.


2011 ◽  
Vol 13 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Nicolas Plachta ◽  
Tobias Bollenbach ◽  
Shirley Pease ◽  
Scott E. Fraser ◽  
Periklis Pantazis

1998 ◽  
Vol 13 (2) ◽  
pp. 82-85 ◽  
Author(s):  
S. Beaudoin ◽  
L. Simon ◽  
J. Simeoni ◽  
P. Sacquin ◽  
F. Bargy

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