scholarly journals Lidocaine spray versus viscous lidocaine solution for pharyngeal local anesthesia in upper gastrointestinal endoscopy: Systematic review and meta‐analysis

2020 ◽  
Author(s):  
Jun Watanabe ◽  
Yusuke Ikegami ◽  
Ayumi Tsuda ◽  
Eiichi Kakehi ◽  
Takeshi Kanno ◽  
...  
Keyword(s):  
Systematic Review ◽  
Local Anesthesia ◽  
Gastrointestinal Endoscopy ◽  
Meta Analysis ◽  
Upper Gastrointestinal Endoscopy ◽  
Lidocaine Solution ◽  
Lidocaine Spray ◽  
Upper Gastrointestinal

scholarly journals Lidocaine lozenges for pharyngeal anesthesia during upper gastrointestinal endoscopy: A randomized controlled trial

2014 ◽  
Vol 05 (02) ◽  
pp. 058-063 ◽  
Author(s):  
Avinash Supe ◽  
Sanjiv P. Haribhakti ◽  
Mohammad Ali ◽  
A. Rathnaswami ◽  
T. Zameer Ulla ◽  
...  
Keyword(s):  
Local Anesthetic ◽  
Global Assessment ◽  
Gastrointestinal Endoscopy ◽  
Controlled Trial ◽  
Controlled Study ◽  
Upper Gastrointestinal Endoscopy ◽  
Open Label ◽  
Gag Reflex ◽  
Lidocaine Spray ◽  
Upper Gastrointestinal

Abstract Background and Objectives: A novel lozenge formulation with advantages of ease of drug administration, palatable taste and improved patient compliance could be the preferred mode of topical pharyngeal anesthesia during upper gastrointestinal endoscopy (UGE). This randomized, open-label, active-controlled study was conducted to evaluate the efficacy and safety of lidocaine lozenges versus lidocaine spray in the diagnostic gastroduodenal endoscopy in Indian patients. Subjects and Methods: Two hundred and forty-seven patients of either sex (18-80 years) undergoing diagnostic gastroduodenal endoscopy were randomized either to; lidocaine lozenge 200 mg or lidocaine spray 200 mg to be applied as a single dose before gastroduodenal endoscopy. Ease of procedure, level of gag reflex, ease of application of the local anesthetic, and investigators global assessment were the primary efficacy endpoints. Need for rescue medication and patient’s global assessment were secondary efficacy endpoints. The incidence of any adverse event was the safety endpoint. Between groups, comparison was done by using appropriate statistical test. Results: Investigator reported significantly lesser procedural difficulty (P = 0.0007) and suppressed gag reflex (P < 0.0001) during UGE with lidocaine lozenge compared to spray. Ease of application of local anesthetic was reported easy in significantly more patients as compared with lidocaine spray (P = 0.001). Global assessment by patient and physician was favorable toward lozenge. Incidences of adverse events were similar in both the groups. Conclusions: The study suggests that lidocaine lozenges are an easier way of applying local oropharyngeal anesthesia, produces better suppression of gag reflex and makes the procedure easier when compared with lidocaine spray.

scholarly journals Bupivacaine Lozenge Compared with Lidocaine Spray as Topical Pharyngeal Anesthetic before Unsedated Upper Gastrointestinal Endoscopy: A Randomized, Controlled Trial

2014 ◽  
Vol 7 ◽  
pp. CGast.S18019 ◽  
Author(s):  
Nesrin Salale ◽  
Charlotte Treldal ◽  
Stine Mogensen ◽  
Mette Rasmussen ◽  
Janne Petersen ◽  
...  
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Controlled Trial ◽  
Primary Objective ◽  
Upper Gastrointestinal Endoscopy ◽  
Patient Discomfort ◽  
Significant Difference ◽  
Group A ◽  
Gag Reflex ◽  
Lidocaine Spray ◽  
Upper Gastrointestinal

Unsedated upper gastrointestinal endoscopy (UGE) can induce patient discomfort, mainly due to a strong gag reflex. The aim was to assess the effect of a bupivacaine lozenge as topical pharyngeal anesthetic compared with standard treatment with a lidocaine spray before UGE. Ninety-nine adult outpatients undergoing unsedated diagnostic UGE were randomized to receive either a bupivacaine lozenge (L-group, n = 51) or lidocaine spray (S-group, n = 42). Primary objective was assessment of patient discomfort including acceptance of the gag reflex during UGE. The L-group assessed the discomfort significantly lower on a visual analog scale compared with the S-group ( P = 0.02). There was also a significant difference in the four-point scale assessment of the gag reflex ( P = 0.03). It was evaluated as acceptable by 49% in the L-group compared with 31% in the S-group. A bupivacaine lozenge compared with a lidocaine spray proved to be a superior option as topical pharyngeal anesthetic before an UGE.

Topical anesthesia with 50 mg of lidocaine spray facilitates upper gastrointestinal endoscopy

1993 ◽  
Vol 39 (3) ◽  
pp. 384-387 ◽  
Author(s):  
D. Gordon Leitch ◽  
Jean Wicks ◽  
Osama A. El Beshir ◽  
Salah A.M. Ali ◽  
Basant K. Chaudhury
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Topical Anesthesia ◽  
Upper Gastrointestinal Endoscopy ◽  
Lidocaine Spray ◽  
Upper Gastrointestinal

scholarly journals Glossopharyngeal Nerve Block versus Lidocaine Spray to Improve Tolerance in Upper Gastrointestinal Endoscopy

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Moisés Ortega Ramírez ◽  
Benigno Linares Segovia ◽  
Marco Antonio García Cuevas ◽  
Jorge Luis Sánchez Romero ◽  
Illich Botello Buenrostro ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Nerve Block ◽  
Gastrointestinal Endoscopy ◽  
Topical Anesthesia ◽  
Glossopharyngeal Nerve ◽  
Upper Gastrointestinal Endoscopy ◽  
Hemodynamic Stability ◽  
Topical Anesthetic ◽  
Lidocaine Spray ◽  
Upper Gastrointestinal

Aim of the Study. To compare the effect of glossopharyngeal nerve block with topical anesthesia on the tolerance of patients to upper gastrointestinal endoscopy.Methods. We performed a clinical trial in one hundred patients undergoing upper gastrointestinal endoscopy. Subjects were randomly assigned to one of the following two groups: (1) treatment with bilateral glossopharyngeal nerve block (GFNB) and intravenous midazolam or (2) treatment with topical anesthetic (TASS) and intravenous midazolam. We evaluated sedation, tolerance to the procedure, hemodynamic stability, and adverse symptoms.Results. We studied 46 men and 54 women, from 17 to 78 years of age. The procedure was reported without discomfort in 48 patients (88%) in the GFNB group and 32 (64%) in the TAAS group; 6 patients (12%) in GFNB group and 18 (36%) in TAAS group reported the procedure as little discomfort (χ2=3.95,P=0.04). There was no difference in frequency of nausea (4% in both groups) and retching, 4% versus 8% for GFNB and TASS group, respectively (P=0.55).Conclusions. The use of glossopharyngeal nerve block provides greater comfort and tolerance to the patient undergoing upper gastrointestinal endoscopy. It also reduces the need for sedation.

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