scholarly journals Novel submucosal injection solution 0.6% sodium alginate: Bench to market for endoscopic submucosal dissection optimization

2019 ◽  
Vol 31 (4) ◽  
pp. 393-395 ◽  
Author(s):  
Koichiro Kawaguchi ◽  
Hajime Isomoto
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Sodium Alginate ◽  
Injection Solution ◽  
Submucosal Injection ◽  
Submucosal Dissection

scholarly journals Ideal submucosal injection solution for colorectal endoscopic submucosal dissection

2019 ◽  
Vol 90 (3) ◽  
pp. 533 ◽  
Author(s):  
Mitsunobu Matsushita ◽  
Yu Takahashi ◽  
Takahiro Wakamatsu ◽  
Akiyoshi Nishio ◽  
Toshihito Seki ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Injection Solution ◽  
Submucosal Injection ◽  
Submucosal Dissection ◽  
Colorectal Endoscopic Submucosal Dissection

Evaluation of 0.6% sodium alginate as a submucosal injection material in endoscopic submucosal dissection for early gastric cancer

2014 ◽  
Vol 26 (5) ◽  
pp. 638-645 ◽  
Author(s):  
Toru Kusano ◽  
Tsuyoshi Etoh ◽  
Tomonori Akagi ◽  
Yoshitake Ueda ◽  
Hidefumi Shiroshita ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Endoscopic Submucosal Dissection ◽  
Sodium Alginate ◽  
Submucosal Injection ◽  
Injection Material ◽  
Submucosal Dissection

scholarly journals Fibrin glue: Novel submucosal injection agent for endoscopic submucosal dissection

2021 ◽  
Vol 09 (03) ◽  
pp. E319-E323
Author(s):  
Madoka Takao ◽  
Yoshitaka Takegawa ◽  
Toshitatsu Takao ◽  
Hiroya Sakaguchi ◽  
Yoshiko Nakano ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Fibrin Glue ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
Submucosal Injection ◽  
Submucosal Dissection ◽  
Vitro Model ◽  
Histopathologic Findings

Abstract Background and study aims Adequate mucosal elevation by submucosal injection is crucial for patient safety and efficiency during endoscopic submucosal dissection (ESD). This study aimed to evaluate the efficacy of fibrin glue (FG) as a long-lasting submucosal injection agent and to evaluate the technical feasibility of FG injection for ESD. Materials and methods To compare the capabilities of different agents in maintaining submucosal evaluation, we injected FG, hyaluronic acid solution, and normal saline into the porcine gastric specimen that was incised into approximately 5 × 5 cm squares. Then, we measured the height of submucosal elevations over time. Moreover, three hypothetical lesions from the resected porcine stomach underwent ESD with FG injection. Thereafter, we conducted macroscopic and histopathologic analyses. Results FG maintained the greatest submucosal elevation among all the injection agents. Three ESD procedures were performed with en bloc resection. Both macroscopic and histopathologic findings showed a thick FG clot on the ulcers. Conclusions The FG solution can be potentially used as an ESD submucosal injection agent in an in vitro model.

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