Endoscopic ultrasonography‐guided diagnosis of pericardial gastrointestinal stromal tumor: First case in the literature (with video)

2019 ◽  
Vol 31 (4) ◽  
pp. 463-463
Author(s):  
Gurhan Sisman ◽  
Erol Barbur ◽  
Davut Şahin
Author(s):  
Kunihiko Matsuno ◽  
Yoshikazu Kanazawa ◽  
Daisuke Kakinuma ◽  
Nobutoshi Hagiwara ◽  
Fumihiko Ando ◽  
...  

AbstractReports of gastric collision tumors, comprising adenocarcinoma and gastrointestinal stromal tumor, are extremely rare. Here, we report the case of a 68-year-old male who was diagnosed with a lower-body, moderately differentiated, tubular-type adenocarcinoma and submucosal tumor and underwent an elective D2 distal gastrectomy. The tumor cells of the gastrointestinal stromal tumor were positive for H-caldesmon and CD117, weakly positive for smooth muscle actin and DOG-1, and negative for desmin, S-100 protein, CD31, and AE1/AE3. The tumor had grown into a mixed form of adenocarcinoma and gastrointestinal stromal tumor. Thus, we report the first case of a preoperatively diagnosed collision tumor in the stomach consisting of adenocarcinoma and gastrointestinal stromal tumor.


Medicine ◽  
2015 ◽  
Vol 94 (37) ◽  
pp. e1549 ◽  
Author(s):  
Attila Kovecsi ◽  
Ioan Jung ◽  
Tivadar Bara ◽  
Tivadar jr. Bara ◽  
Leonard Azamfirei ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Areen Abdulelah Murshid ◽  
Hatim Q. Al-Maghraby

Desmoid tumors (deep fibromatosis) of the mesentery are rare mesenchymal tumors. They are often misdiagnosed, especially with a previous history of resection for gastrointestinal stromal tumor (GIST). Immunohistochemistry can help differentiate between these two tumors. In this article, we present a case we had encountered: a Desmoid tumor developing in a patient with a history of GIST 3 years ago. It is the first case of GIST with subsequent development of Desmoid tumor to be reported in Saudi Arabia. We discuss the two entities of Desmoid tumor and GIST by comparing their definitions, clinical presentations, histological features, immunohistochemistry stains, molecular pathogenesis, prognosis, and treatment. We also discuss the relationship between GIST and the subsequent development of Desmoid tumors and compare our case with case reports in literature.


2021 ◽  
Vol 5 (6) ◽  
pp. 433-437
Author(s):  
T.E. Skvortsova ◽  
◽  
I.A. Oganezova ◽  
O.I. Medvedeva ◽  
O.M. Zhorina ◽  
...  

Gastrointestinal stromal tumors (GIST) are the most common malignant submucosal neoplasms of the gastrointestinal tract, with predominant localization in the stomach and small intestine. The disease pattern is the absence of specific clinical signs, at least a third of cases are detected during examinations or surgical interventions for other diseases or at an autopsy. The examination algorithm of patients with suspected GIST includes endoscopic and radiation diagnostic methods, including a number of high-tech and expensive techniques, such as endoscopic ultrasonography, computed tomography, immunohistochemical and molecular genetic methods for studying biopsy material. Only conducting a full set of examinations will allow timely diagnosis and choosing the optimal treatment tactics for the disease with a high risk of malignancy. The authors present their own clinical case of a patient, female, with GIST, which is of considerable interest to clinicians. The above clinical case represents a typical clinical and morphological picture of GIST. The disease onset occurred in a patient over the age of 60 years and proceeded under the guise of organic dyspepsia. In this case, the use of expensive high-tech techniques allowed to verify the diagnosis of GIST and refer the patient to surgical treatment. KEYWORDS: gastrointestinal stromal tumor, stomach tumor, endoscopic ultrasonography, immunohistochemistry, differential diagnosis. FOR CITATION: Skvortsova T.E., Oganezova I.A., Medvedeva O.I. et al. Gastrointestinal stromal tumor of the stomach (clinical case). Russian Medical Inquiry. 2021;5(6):433–437 (in Russ.). DOI: 10.32364/2587-6821-2021-5-6-433-437.


2016 ◽  
Vol 89 (1) ◽  
pp. 94-95
Author(s):  
Minoru Tomizawa ◽  
Fuminobu Shinozaki ◽  
Kazunori Fugo ◽  
Yasufumi Motoyoshi ◽  
Takao Sugiyama ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Andréanne Gagné ◽  
Olga Sazonova ◽  
Simon Marceau ◽  
Martine Périgny ◽  
Philippe Joubert

Objectives. Duplication cysts are rare benign lesions usually arising in the gastrointestinal tract. We report a case of a 52-year-old woman with an incidental gastric mass found on computed tomography during a pregraft workup for a familial cardiomyopathy.Methods. The mass was completely excised by partial gastrectomy and gross examination revealed a cystic lesion containing two small solid nodules in its wall. Microscopic evaluation and immunohistochemistry study were performed to further characterize the cyst and the nodules. A comprehensive literature review of the NCBI database PubMed was also carried out.Results. While the cyst was diagnosed as a foregut duplication cyst, the solid nodules proved to be concomitant gastrointestinal stromal tumor (GIST) and leiomyoma. Both morphologic features and immunohistochemistry stains, including CD117, smooth muscle actin, and CD34 supported the diagnosis. Clinical course was benign and the patient had no clinical evidence of relapse ten months following the surgical procedure. The literature search did not reveal any other published case of a foregut duplication cyst presenting in combination with a GIST and a leiomyoma.Conclusions. To our knowledge, this is the first case of a composite lesion comprising a foregut duplication cyst of the stomach along with a leiomyoma and a GIST.


2015 ◽  
Vol 26 ◽  
pp. iv34
Author(s):  
J.-O. Kim ◽  
S.R. Jeon ◽  
H.G. Kim ◽  
T.H. Lee ◽  
J.S. Lee ◽  
...  

2017 ◽  
Vol 4 ◽  
pp. 375-380 ◽  
Author(s):  
Barbara Zegarska ◽  
Maciej Nowacki ◽  
Katarzyna Pietkun ◽  
Wojciech Jozwicki ◽  
Tomasz Nowikiewicz ◽  
...  

2005 ◽  
Vol 129 (5) ◽  
pp. e121-e123
Author(s):  
Joseph L. Sailors ◽  
Samuel W. French

Abstract Granular cell tumors are generally benign oncocytoid lesions of schwannian origin that are often incidental findings in many locations. Gastrointestinal stromal tumors occur in older adults and express the c-Kit protein (CD117). Both of these tumors have been described in association with many other entities; however, they have never been reported to occur jointly. This report is prompted by the simultaneous appearance of 2 granular cell tumors, a gastrointestinal stromal tumor, and a gastric adenocarcinoma in a 65-year-old woman with a history of breast carcinoma and granular cell tumor. To our knowledge, this is the first case report of these tumors occurring simultaneously.


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