Endoscopic tissue shielding with polyglycolic acid sheets, fibrin glue and clips to prevent delayed perforation after duodenal endoscopic resection

2014 ◽  
Vol 26 ◽  
pp. 41-45 ◽  
Author(s):  
Hisashi Doyama ◽  
Kei Tominaga ◽  
Naohiro Yoshida ◽  
Kenichi Takemura ◽  
Shinya Yamada
Keyword(s):  
Fibrin Glue ◽  
Endoscopic Resection ◽  
Polyglycolic Acid ◽  
Delayed Perforation

scholarly journals Usefulness of Polyglycolic acid (PGA) sheets and fibrin glue treatment for duodenal endoscopic resection

2015 ◽  
Vol 87 (1) ◽  
pp. 150-151
Author(s):  
Masakazu Abe ◽  
Chika Kusano ◽  
Sho Suzuki ◽  
Mikinori Koga ◽  
Shin Kono ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Endoscopic Resection ◽  
Polyglycolic Acid

scholarly journals Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Satoshi Abiko ◽  
Soichiro Oda ◽  
Akimitsu Meno ◽  
Akane Shido ◽  
Sonoe Yoshida ◽  
...  
Keyword(s):  
High Risk ◽  
Endoscopic Submucosal Dissection ◽  
Median Time ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Low Risk ◽  
R0 Resection ◽  
Antithrombotic Agents ◽  
Delayed Bleeding ◽  
Submucosal Dissection

Abstract Background Methods have been developed for preventing delayed bleeding (DB) after gastric endoscopic submucosal dissection (GESD). However, none of the methods can completely prevent DB. We hypothesized that DB could be prevented by a modified search, coagulation, and clipping (MSCC) method for patients at low risk for DB and by combining the use of polyglycolic acid sheets and fibrin glue with the MSCC method (PMSCC method) for patients at high risk for DB (antibleeding [ABI] strategy). This study assessed the technical feasibility of this novel strategy. Method We investigated 123 lesions in 121 consecutive patients who underwent GESD in Kushiro Rosai Hospital between April 2018 and January 2020. The decision for continuation or cessation of antithrombotic agents was based on the Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment. Results Oral antithrombotic agents were administered to 28 patients (22.8%). The en bloc R0 resection rate was 98.4%. The MSCC method and the PMSCC method for preventing DB were performed in 114 and 9 lesions, respectively. The median time of the MSCC method was 16 min, and the median speed (the resection area divided by the time of method used) was 3.6 cm2/10 min. The median time of the PMSCC method was 59 min, and the median speed was 1.3 cm2/10 min. The only delayed procedural adverse event was DB in 1 (0.8%) of the 123 lesions. Conclusions The ABI strategy is feasible for preventing DB both in patients at low risk and in those at high risk for DB after GESD, whereas the PMSCC method may be necessary for reduction of time.

Endoscopic Resections in Inflammatory Bowel Disease: A Multicentre European Outcomes Study

2019 ◽  
Vol 13 (11) ◽  
pp. 1394-1400
Author(s):  
A Alkandari ◽  
S Thayalasekaran ◽  
M Bhandari ◽  
A Przybysz ◽  
M Bugajski ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Endoscopic Resection ◽  
Bowel Disease ◽  
En Bloc ◽  
Increased Risk ◽  
Delayed Perforation ◽  
Inflammatory Bowel ◽  
Outcomes Study ◽  
Almost All ◽  
Current Guidelines

Abstract Background and Aims Inflammatory bowel disease is associated with an increased risk of colorectal cancer, with estimates ranging 2–18%, depending on the duration of colitis. The management of neoplasia in colitis remains controversial. Current guidelines recommend endoscopic resection if the lesion is clearly visible with distinct margins. Colectomy is recommended if complete endoscopic resection is not guaranteed. We aimed to assess the outcomes of all neoplastic endoscopic resections in inflammatory bowel disease. Methods This was a multicentre retrospective cohort study of 119 lesions of visible dysplasia in 93 patients, resected endoscopically in inflammatory bowel disease. Results A total of 6/65 [9.2%] lesions <20 mm in size were treated by ESD [endoscopic submucosal dissection] compared with 59/65 [90.8%] lesions <20 mm treated by EMR [endoscopic mucosal resection]; 16/51 [31.4%] lesions >20 mm in size were treated by EMR vs 35/51 [68.6%] by ESD. Almost all patients [97%] without fibrosis were treated by EMR, and patients with fibrosis were treated by ESD [87%], p < 0.001. In all, 49/78 [63%] lesions treated by EMR were resected en-bloc and 27/41 [65.9%] of the ESD/KAR [knife-assisted resection] cases were resected en-bloc, compared with 15/41 [36.6%] resected piecemeal. Seven recurrences occurred in the cohort. Seven complications occurred in the cohort; six were managed endoscopically and one patient with a delayed perforation underwent surgery. Conclusions Larger lesions with fibrosis are best treated by ESD, whereas smaller lesions without fibrosis are best managed by EMR. Both EMR and ESD are feasible in the management of endoscopic resections in colitis.

scholarly journals Nonsuture dural repair using polyglycolic acid mesh and fibrin glue: clinical application to spinal surgery

2006 ◽  
Vol 65 (2) ◽  
pp. 136-142 ◽  
Author(s):  
Kazutoshi Hida ◽  
Satoshi Yamaguchi ◽  
Toshitaka Seki ◽  
Shunsuke Yano ◽  
Minoru Akino ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Clinical Application ◽  
Spinal Surgery ◽  
Polyglycolic Acid ◽  
Dural Repair ◽  
Polyglycolic Acid Mesh

scholarly journals Fibrin adhesive and the vaginal vault synthesis on female rabbits abdominal hysterectomies

2009 ◽  
Vol 24 (1) ◽  
pp. 30-35 ◽  
Author(s):  
Ari Gonçalves Lima ◽  
Murched Omar Taha ◽  
Henri Chaplin Rivoire ◽  
Anna Tereza Negrini Fagundes ◽  
Djalma José Fagundes
Keyword(s):  
Fibrin Glue ◽  
Granulation Tissue ◽  
Fibrous Tissue ◽  
Rabbit Model ◽  
Abdominal Hysterectomy ◽  
Polyglycolic Acid ◽  
Vaginal Vault ◽  
Fisher Test ◽  
Burst Test ◽  
Significant Difference

PURPOSE: To investigate the effectiveness of fibrin glue in comparison with polyglycolic acid suture to promote the closure of rabbit's vaginal vault, after abdominal hysterectomy. METHODS: Twenty female, adults, New Zealand rabbits, were submitted to abdominal hysterectomy and randomly distributed to polyglycolic acid suture (G-PA / n=10) or fibrin glue closure of vaginal vault (G-FG / n=10). Radiograph study allowed identifying vault vaginal suture disrupter or fistulas to urinary bladder or rectum. Videovaginoscopy study allowed identifying the presence of cellulites, abscess formation, tissue granulation or granuloma. Vaginal cuff burst test allowed to identify by the escape of air bubbles and rupture pression record. Histological sections stained with Picrosirius red allowed the measure of fibrous tissue healing. RESULTS: The videovaginoscopy identified a significant difference (Fisher Test p<0.3142) of granulation tissue in the animals of G-PA (40%) in comparison with the G-FG (20%). The gross inspection showed the same relation in the granulation tissue occurrence (Fisher test p< 0.1749) with G-PA (50%) and G-FB (20%). The visceral adhesion to the vaginal vault wound was statistical significant (Fisher test p< 0.1749) with G-PA (50%) and G-FG (20%). The pressure of rupture (mm Hg) of the burst test was similar (p<0.0421) in the animals of G-PA (61.5±19.3) and G-FG (72.5±21.9). The collagen matrix of vault wound healing was similar (p< 0.0231) between the G-PA (31.63±15) and the G-FG (23.2±13.2). CONCLUSION: The vaginal vault closure using the fibrin glue is a safe and reliable procedure after abdominal hysterectomy in female rabbit model.

Use of fibrin glue sealant with polyglycolic acid sheets to prevent pancreatic fistula formation after laparoscopic-assisted gastrectomy

Surgery Today ◽  
2012 ◽  
Vol 43 (5) ◽  
pp. 527-533 ◽  
Author(s):  
Yuichiro Hiura ◽  
Shuji Takiguchi ◽  
Kazuyoshi Yamamoto ◽  
Yukinori Kurokawa ◽  
Makoto Yamasaki ◽  
...  
Keyword(s):  
Pancreatic Fistula ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Fistula Formation ◽  
Fibrin Glue Sealant ◽  
Laparoscopic Assisted
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