scholarly journals Sichere topische Behandlung der digitalen Calcinosis cutis mit Natriumthiosulfat–Fallserie mit sechs Patienten

2020 ◽  
Vol 18 (10) ◽  
pp. 1181-1183
Author(s):  
Christina Hodenberg ◽  
Matthias Neufeld ◽  
Johannes Wohlrab ◽  
Doris Meyer ◽  
Jan Ehrchen ◽  
...  
Keyword(s):  
Calcinosis Cutis ◽  
Topische Behandlung

Krätzeausbruch im Altenheim: Konsequente topische Behandlung als Alternative zur Massenchemotherapie

2014 ◽  
Vol 76 (04) ◽  
Author(s):  
B Böddinghaus ◽  
U Götsch ◽  
F Velten ◽  
A Walczok ◽  
R Gottschalk
Keyword(s):  
Topische Behandlung

A Case of Milia-like Idiopathic Calcinosis Cutis in Down Syndrome

2008 ◽  
Vol 70 (6) ◽  
pp. 621-624
Author(s):  
Yoshio ITO ◽  
Tetsuo SASAKI ◽  
Yoshiko YATA ◽  
Junko KAWASHIMA ◽  
Shinichi TAKAHASHI
Keyword(s):  
Down Syndrome ◽  
Calcinosis Cutis

Milia-like Idiopathic Calcinosis Cutis in Down Syndrome.

2000 ◽  
Vol 62 (4) ◽  
pp. 466-468 ◽  
Author(s):  
Yoshihiro UMEBAYASHI ◽  
Shusaku ITO ◽  
Ken NAGAYAMA
Keyword(s):  
Down Syndrome ◽  
Calcinosis Cutis

Limited cutaneous systemic sclerosis: Total rehabilitation with fixed prosthesis on dental implants

2021 ◽  
pp. 239719832110043
Author(s):  
Miguel Angel Garcés Villalá ◽  
Carolina Zorrilla Albert
Keyword(s):  
Systemic Sclerosis ◽  
Bone Loss ◽  
Dental Implants ◽  
Social Life ◽  
Connective Tissue Diseases ◽  
The Body ◽  
Calcinosis Cutis ◽  
Complex Disorders ◽  
Standardized Parameters

Introduction: Limited cutaneous systemic sclerosis with special manifestations (calcinosis cutis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) is part of the group of connective tissue diseases, these rare autoimmune systemic pathologies cause thickening and hardening of tissues in different parts of the body and can lead to complex disorders. Oral manifestations of systemic sclerosis may include limited ability to open the mouth, xerostomia, periodontal disease, enlarged periodontal ligament, and bone resorption of the jaw. Case Description: A 54-year-old Caucasian patient presented with oral pain, swallowing, phonation and chewing difficulties associated with dental instability, hygiene/handling difficulties and her main problem with microstomia, which prevented her from removing the skeletal prosthesis for 4 years, depriving her of social life. Gradual treatment with dental implants was diagnosed and planned to support a fixed total denture adapted to the ridge with self-cleaning characteristics. After implant insertion, panoramic radiographs with standardized parameters were taken to compare crestal bone levels at the time of prosthesis placement and with 10 years of follow-up. Conclusion: The average crestal bone loss of the 12 implants after the 10 years of follow-up was 1.26 mm for the maxilla and 1.17 mm for the mandible. The survival of the 12 support implants of two total fixed prostheses in a clinical/radiographic follow-up of 10 years was 100%. After 10 years of follow-up, the 12 implants inserted had a bone loss similar to that of healthy patients and no pathologies were registered, recovering function, aesthetics, and self-esteem. This therapy must be implemented before the interincisal distance decreases to 30 mm to allow intraoral surgical/prosthetic access. Implant-supported total fixed rehabilitation is a viable, predictable, and recommended therapy in patients with limited cutaneous systemic sclerosis.

scholarly journals Local, non-systemic, and minimally invasive therapies for calcinosis cutis: a systematic review

2021 ◽  
Author(s):  
Joanna Nowaczyk ◽  
Michał Zawistowski ◽  
Piotr Fiedor
Keyword(s):  
Systematic Review ◽  
Complete Remission ◽  
Minimally Invasive ◽  
Subcutaneous Tissue ◽  
Sodium Thiosulfate ◽  
Common Adverse Event ◽  
Chronic Infections ◽  
Level Of Evidence ◽  
Calcinosis Cutis ◽  
Extracorporeal Shock Wave

AbstractCalcinosis cutis is a deposition of calcium in the skin and subcutaneous tissue, often accompanied by pain, reduced mobility, and chronic infections. Limited evidence is available about the feasibility and efficacy of therapies alternative to systemic treatment and surgical excision, both of which often lead to unsatisfactory results or complications. We conducted a systematic review to evaluate the efficacy and safety of topical and intralesional sodium thiosulfate, extracorporeal shock-wave lithotripsy (ESWL), and laser for calcinosis cutis. PubMed, Embase, and Web of Science were searched. Reports of calciphylaxis and treatment combined with systemic medications were excluded. A total of 40 studies including 136 patients were analysed. Partial or complete remission after monotherapy was observed in 64% to 81% of cases. Self-applied topical sodium thiosulfate required patient’s adherence (mean treatment duration, 4.9 months; range 2–24). Laser therapy enabled complete remission of microcalcifications after a single procedure (57%; 12/21). ESWL and intralesional sodium thiosulfate injections decreased calcinosis-associated pain (median reduction in VAS score, 3; range 0–9 and 1; range 0–5, respectively). The most common adverse event was scarring and hyperkeratosis, observed after CO2 laser (56%; 10/18). Intralesional sodium thiosulfate injections caused transient pain in over 11% of patients. Recurrences within the follow-up were rare (2%; 3/136). This study provides an overview of minimally invasive and local therapies that in selected cases might transcend conventional treatment. The limitation of this study is the poor level of evidence, which emerges mainly from non-randomized studies at high risk of bias.

Congenital Bilateral Calcinosis Cutis of the Hands

2006 ◽  
Vol 31 (5) ◽  
pp. 522-523
Author(s):  
N. WHITE ◽  
D. L. CHESTER ◽  
A. KHANNA
Keyword(s):  
Calcium Phosphate ◽  
Calcinosis Cutis ◽  
Calcium Deposits

Calcinosis cutis is the cutaneous deposition of calcium phosphate. We present the first reported case of symmetrical calcium deposits being present in both hands at birth.

SAT0469 Calcinosis Cutis in Poly-Dermatomyositis: Clinical and Therapeutic Study

2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 830.2-831 ◽  
Author(s):  
M. Fredi ◽  
F. Bartoli ◽  
I. Cavazzana ◽  
N. Carabellese ◽  
A. Ceribelli ◽  
...  
Keyword(s):  
Calcinosis Cutis ◽  
Therapeutic Study
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