Keratosis lichenoides chronica with an atypical clinical presentation and variable histopathological features

2016 ◽  
Vol 14 (11) ◽  
pp. 1136-1139 ◽  
Author(s):  
Alessia Barisani ◽  
Francesco Savoia ◽  
Paola Sgubbi ◽  
Massimino Negosanti ◽  
Salvatore Domenico Infusino ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Histopathological Features ◽  
Atypical Clinical Presentation

scholarly journals Atypical Clinical Presentation of Laryngopharyngeal Reflux: A 5-Year Case Series

2021 ◽  
Vol 10 (11) ◽  
pp. 2439
Author(s):  
Jerome R. Lechien ◽  
Stéphane Hans ◽  
Francois Bobin ◽  
Christian Calvo-Henriquez ◽  
Sven Saussez ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Laryngopharyngeal Reflux ◽  
Case Series ◽  
Clinical Findings ◽  
Aerodigestive Tract ◽  
Common Disease ◽  
Upper Aerodigestive Tract ◽  
Suppurative Otitis Media ◽  
Adequate Treatment ◽  
Atypical Clinical Presentation

Background: Laryngopharyngeal reflux (LPR) is a common disease in otolaryngology characterized by an inflammatory reaction of the mucosa of the upper aerodigestive tract caused by digestive refluxate enzymes. LPR has been identified as the etiological or favoring factor of laryngeal, oral, sinonasal, or otological diseases. In this case series, we reported the atypical clinical presentation of LPR in patients presenting in our clinic with reflux. Methods: A retrospective medical chart review of 351 patients with LPR treated in the European Reflux Clinic in Brussels, Poitiers and Paris was performed. In order to be included, patients had to report an atypical clinical presentation of LPR, consisting of symptoms or findings that are not described in the reflux symptom score and reflux sign assessment. The LPR diagnosis was confirmed with a 24 h hypopharyngeal-esophageal impedance pH study, and patients were treated with a combination of diet, proton pump inhibitors, and alginates. The atypical symptoms or findings had to be resolved from pre- to posttreatment. Results: From 2017 to 2021, 21 patients with atypical LPR were treated in our center. The clinical presentation consisted of recurrent aphthosis or burning mouth (N = 9), recurrent burps and abdominal disorders (N = 2), posterior nasal obstruction (N = 2), recurrent acute suppurative otitis media (N = 2), severe vocal fold dysplasia (N = 2), and recurrent acute rhinopharyngitis (N = 1), tearing (N = 1), aspirations (N = 1), or tracheobronchitis (N = 1). Abnormal upper aerodigestive tract reflux events were identified in all of these patients. Atypical clinical findings resolved and did not recur after an adequate antireflux treatment. Conclusion: LPR may present with various clinical presentations, including mouth, eye, tracheobronchial, nasal, or laryngeal findings, which may all regress with adequate treatment. Future studies are needed to better specify the relationship between LPR and these atypical findings through analyses identifying gastroduodenal enzymes in the inflamed tissue.

scholarly journals Perforated Meckel’s Diverticulitis in a Patient with Unknown Intestinal Malrotation: Clinical Pitfall

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Marie Burgard ◽  
Floryn Cherbanyk ◽  
François Pugin ◽  
Bernhard Egger
Keyword(s):  
Acute Appendicitis ◽  
Clinical Presentation ◽  
Final Diagnosis ◽  
Intestinal Malrotation ◽  
Radiological Imaging ◽  
Atypical Clinical Presentation ◽  
Lower Abdominal Quadrant ◽  
Meckel’S Diverticulitis ◽  
The Right ◽  
Abdominal Quadrant

Symptomatic Meckel’s diverticulum is rare in adults. The most frequent complications are intestinal obstruction and diverticulitis. Diagnosis of Meckel’s diverticulitis can be challenging due to nonspecific clinical manifestation of pain in the right lower abdominal quadrant, mimicking acute appendicitis. If associated with congenital malformation, such as intestinal malrotation, the anomalous anatomy makes the diagnosis even more challenging. In such cases, radiological imaging is essential to guide further management. We present a case of Meckel’s diverticulitis in which physicians were initially misguided because of the atypical clinical presentation. Yet, anamnestic details directed to a potential underlying malformation, leading to supplementary radiological examination and the final diagnosis.

scholarly journals Atypical clinical presentation of a WT1-related syndrome associated with a novel exon 6 gene mutation

2013 ◽  
Vol 2013 (may27 1) ◽  
pp. bcr2013009543-bcr2013009543 ◽  
Author(s):  
P. Dattolo ◽  
M. Allinovi ◽  
P. Iatropoulos ◽  
S. Michelassi
Keyword(s):  
Gene Mutation ◽  
Clinical Presentation ◽  
Atypical Clinical Presentation ◽  
Novel Exon

scholarly journals The Importance of Happy Hypoxemia in COVID-19

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Katayoun Haryalchi ◽  
Abtin Heidarzadeh ◽  
Mahmood Abedinzade ◽  
Sepehr Olangian Tehrani ◽  
Samaneh Ghazanfar Tehran
Keyword(s):  
Health Status ◽  
Web Of Science ◽  
Clinical Presentation ◽  
Specific Treatment ◽  
Lung Compliance ◽  
Google Scholar ◽  
Normal Lung ◽  
Severe Hypoxemia ◽  
Atypical Clinical Presentation ◽  
The World

Background: Nowadays, the new coronavirus (SARS-CoV-2) and its complications are one of the main concerns of the world. One of the most severe complications of COVID-19 is hypoxemia. Objectives: This study aimed to assess the importance of happy hypoxemia in COVID-19. Methods: We systematically searched web of science, PubMed, and Google scholar databases to find articles related to COVID-19 and happy hypoxemia. Results: COVID-19 causes a type of hypoxemia named silent (happy) hypoxemia, which has an atypical clinical presentation. This type of hypoxemia has not been noted before in viral pneumonia, and there is no specific treatment for this serious complication. Patients with silent hypoxemia may develop severe hypoxemia without dyspnea and with near-normal lung compliance. These patients are awake, calm, and responsive. Although their lungs are not oxygenated efficiently, they are alert and cooperative. Their condition may be deteriorated rapidly without warning and causes death. Conclusions: According to the findings, paying attention to happy hypoxemia is important for improving the health status of COVID-19 patients.

Possible Fatal Acetaminophen Intoxication with Atypical Clinical Presentation

2013 ◽  
Vol 58 (5) ◽  
pp. 1397-1400 ◽  
Author(s):  
Fabio De-Giorgio ◽  
Maria Lodise ◽  
Marcello Chiarotti ◽  
Ernesto d'Aloja ◽  
Arnaldo Carbone ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Atypical Clinical Presentation ◽  
Acetaminophen Intoxication

Merkel Cell Carcinoma on a Sternotomy Scar: Atypical Clinical Presentation

2015 ◽  
Vol 33 (5) ◽  
pp. e22-e24 ◽  
Author(s):  
Francesca R. Grippaudo ◽  
Brando Costantino ◽  
Fabio Santanelli
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Clinical Presentation ◽  
Merkel Cell ◽  
Atypical Clinical Presentation
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