Perceived barriers to utilise methadone maintenance therapy among male injection drug users in rural areas of southern Thailand

2015 ◽  
Vol 34 (6) ◽  
pp. 645-653 ◽  
Author(s):  
Roongnapa Khampang ◽  
Sawitri Assanangkornchai ◽  
Yot Teerawattananon
Keyword(s):  
Maintenance Therapy ◽  
Rural Areas ◽  
Injection Drug Users ◽  
Drug Users ◽  
Methadone Maintenance ◽  
Methadone Maintenance Therapy ◽  
Injection Drug ◽  
Perceived Barriers ◽  
Southern Thailand

Barriers and facilitators to methadone maintenance therapy use among illicit opiate injection drug users in Vancouver

2006 ◽  
Vol 2 (1) ◽  
pp. 35 ◽  
Author(s):  
Cody Callon, BSc ◽  
Evan Wood, PhD ◽  
David Marsh, MD ◽  
Kathy Li, PhD ◽  
Julio Montaner, MD ◽  
...  
Keyword(s):  
Maintenance Therapy ◽  
Injection Drug Users ◽  
Drug Users ◽  
Addiction Treatment ◽  
User Study ◽  
Crack Cocaine ◽  
Methadone Maintenance ◽  
Methadone Maintenance Therapy ◽  
Injection Drug ◽  
Downtown Eastside

Methadone maintenance therapy (MMT) has been increasingly implemented as the treatment of choice for opiate-addicted individuals and has been associated with reduced harm related to opiate addiction. Barriers to MMT uptake still exist, however, and many opiate-addicted individuals do not access this form of treatment.We examined barriers to and facilitators of MMT access among opiate users enrolled in a prospective cohort study of injection drug users (IDUs). We identified individuals who had initiated MMT during follow-up interviews and used generalized estimating equations to identify sociodemographic and drug-related variables associated with MMT access.Of the 1,587 participants recruited into the Vancouver Injection Drug User Study, 1,463 individuals were eligible for the present analysis. Factors negatively associated with MMT use included male gender (odds ratio [OR] = 0.41; 95 percent confidence interval [CI], 0.32 to 0.52), Aboriginal ethnicity (OR = 0.37; 95 percent CI, 0.29 to 0.48), recent incarceration (OR = 0.82; 95 percent CI, 0.72 to 0.93), Downtown Eastside residence (OR = 0.86; 95 percent CI, 0.75 to 0.97), sex-trade involvement (OR = 0.80; 95 percent CI, 0.67 to 0.95), syringe lending (OR = 0.76; 95 percent CI, 0.66 to 0.89), denied addiction treatment (OR = 0.81; 95 percent CI, 0.68 to 0.96), heroin injection (OR = 0.51; 95 percent CI, 0.44 to 0.59), nonfatal overdose (OR = 0.59; 95 percent CI, 0.51 to 0.68), and injecting in public (OR = 0.75; 95 percent CI, 0.63 to 0.89). Older age (OR = 1.03; 95 percent CI, 1.01 to 1.04), human immunodeficiency virus (HIV) positivity (OR = 1.89; 95 percent CI, 1.52 to 2.23), and crack cocaine smoking (OR = 1.41; 95 percent CI, 1.22 to 1.62) were positively associated with MMT use.Our study identified a large number of barriers to and facilitators of MMT use among IDUs. While some populations such as HIV-positive individuals are frequently accessing MMT, identified barriers among men and Aboriginal IDUs are of great concern. These findings indicate the need for additional interventions aimed at maximizing coverage of MMT and other treatments for opiateaddicted individuals.

scholarly journals Methadone maintenance therapy promotes initiation of antiretroviral therapy among injection drug users

Addiction ◽  
2010 ◽  
Vol 105 (5) ◽  
pp. 907-913 ◽  
Author(s):  
Sasha Uhlmann ◽  
M.-J. Milloy ◽  
Thomas Kerr ◽  
Ruth Zhang ◽  
Silvia Guillemi ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Maintenance Therapy ◽  
Injection Drug Users ◽  
Drug Users ◽  
Methadone Maintenance ◽  
Methadone Maintenance Therapy ◽  
Injection Drug

No Increase in HIV Drug Resistance Mutations among Injecting Drug Users on Methadone Maintenance Therapy: A Prospective Cohort Study

2020 ◽  
Vol 18 (5) ◽  
pp. 362-372
Author(s):  
Chunyuan Huang ◽  
Li Ye ◽  
Abu S Abdullah ◽  
Bingyu Liang ◽  
Junjun Jiang ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Maintenance Therapy ◽  
Prospective Cohort ◽  
Drug Users ◽  
Methadone Maintenance ◽  
Injecting Drug Users ◽  
Methadone Maintenance Therapy ◽  
Hiv Positive ◽  
Resistance Mutations ◽  
Drug Resistance Mutations

Background: Whether HIV-positive injecting drug users (IDUs) are at higher risk of developing drug resistance mutations (DRMs) after methadone maintenance therapy (MMT) than any other HIV-positive population is unclear. Objective: To compare the incidence of new DRMs in two population groups: antiretroviraltreatment (ART) HIV-positive IDUs and non-drug users. Methods: A prospective cohort of ART HIV-positive patients including IDUs who received MMT (MMT group) and non-drug users (N-MMT group) was established from April 2016 to December 2017 in Guangxi, China. Results: Of the 80 participants, 43 were in the MMT group and 37 were in the N-MMT group. Compared with the N-MMT group, the HRs of PIs, NRTIs and NNRTIs for new DRMs in the MMT group was 1.55 (95%CI: 0.28-8.64; P = 0.616), 1.51 (95%CI: 0.44-5.20; P = 0.512) and 0.45 (95%CI: 0.15-1.35; P = 0.155), respectively. There was no dose-response relationship between MMT and new DRMs for PIs, NRTIs and NNRTIs (P > 0.05). The new DRM incidence for NRTIs (138.23 per 104 person-months) was higher than for PIs (94.16 per 104 person-months) and NNRTIs (95.41per 104 person-months) in the MMT group, while the new DRM incidence for NNRTIs (208.24 per 104 person-months) was higher than for PIs (44.13 per 104 person-months) and NRTIs (91.78 per 104 person-months) in the N-MMT group. Conclusion: Among ART HIV-positive patients, there is no significant difference in the incidence of new DRMs between IDUs receiving MMT and non-drug users. MMT has little impact on the development of DRMs among IDUs.

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