Diagnostic accuracy of FNAC and cyto-histopathological correlation in testicular and paratesticular mass lesions

Cytopathology ◽  
2017 ◽  
Vol 28 (6) ◽  
pp. 542-548 ◽  
Author(s):  
A. D. Singh ◽  
F. A. Wani ◽  
S. Bhardwaj
Keyword(s):  
Diagnostic Accuracy ◽  
Histopathological Correlation ◽  
Mass Lesions ◽  
Paratesticular Mass

scholarly journals The Diagnostic Accuracy of Integrated Positron Emission Tomography/Computed Tomography in the Evaluation of Pulmonary Mass Lesions in a Tuberculosis-Endemic Area

CHEST Journal ◽  
2015 ◽  
Vol 148 (4) ◽  
pp. 511A
Author(s):  
Coenraad Koegelenberg ◽  
Rudolf du Toit ◽  
Jane Shaw ◽  
Florian von Groote-Bidlingmaier ◽  
James Warwick ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Diagnostic Accuracy ◽  
Endemic Area ◽  
Emission Tomography ◽  
Pulmonary Mass ◽  
Positron Emission ◽  
Mass Lesions

scholarly journals Comparison of 22G standard and Franseen needles in endoscopic ultrasound-guided fine-needle aspiration for diagnosing pancreatic mass lesions: Study protocol for a controlled trial

Trials ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Masahiro Itonaga ◽  
Satoru Yasukawa ◽  
Toshio Shimokawa ◽  
Mamoru Takenaka ◽  
Nobuyasu Fukutake ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Diagnostic Performance ◽  
Controlled Trial ◽  
Needle Aspiration ◽  
Pancreatic Mass ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Mass Lesions

Abstract Background Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) was developed with the aim of further improving the diagnostic performance of endoscopic ultrasound. Although novel puncture needles have been specifically designed for collecting sufficient tissue specimens, clinical studies have indicated no clear difference in diagnostic performance between these novel needles and conventional puncture needles. Recently, a needle with Franseen geometry was developed specifically for EUS-FNA biopsy. Due to the characteristic shape of its tip, the Franseen needle is expected to be effective for scraping tissues, thus potentially increasing the diagnostic accuracy of EUS-FNA biopsy. We plan to carry out a prospective, multicenter, open-labeled, controlled trial to compare conventional and Franseen needles in terms of the diagnostic accuracy of EUS-FNA for evaluating the malignancy of pancreatic mass lesions. Methods/design The study will enroll 520 patients with pancreatic mass managed at any of 21 participating endoscopic centers. Lesion samples obtained using 22G conventional and Franseen needles will be assessed to compare the efficacy and safety of these two types of needles in EUS-FNA for evaluating the malignancy of mass lesions in the pancreas. Tissue samples will be fixed in formalin and processed for histologic evaluation. For the purpose of this study, only samples obtained with the first needle pass will be used for comparing the: (i) accuracy of the malignancy diagnosis, (ii) sensitivity and specificity for the malignancy diagnosis, (iii) procedure completion rate, (iv) sample cellularity, and (v) incidence of complications. Patient enrollment begins on July 17, 2018. Discussion The outcomes of this study may provide insight into the optimal needle choice for evaluating the malignancy of pancreatic solid lesions, thus aiding in the development of practice guidelines for pancreatic diseases. Trial registration University Hospital Medical Information Network Clinical Trials Registry (UMIN-CTR), UMIN000030634. Registered on 29 December 2017. http://www.umin.ac.jp/ Version number: 01.2017.12.28.

scholarly journals COMPARATIVE STUDY OF USG B-MODE AND DOPPLER IN EVALUATION OF OVARIAN MASS LESIONS

2021 ◽  
pp. 1-2
Author(s):  
Alka Agrawal ◽  
P.S. Tripathi ◽  
Gaurav Bhandari ◽  
Soorya K ◽  
Prachi Shukla
Keyword(s):  
Ovarian Cancer ◽  
Comparative Study ◽  
Diagnostic Accuracy ◽  
Diagnostic Performance ◽  
Imaging Modality ◽  
Ovarian Mass ◽  
Doppler Evaluation ◽  
Mass Lesions

Background: Ovarian cancer is highly lethal due to delayed detection. Ovarian lesions display a myriad of findings on imaging. Knowledge of these is essential to make a diagnosis or list the differentials. USG remains the mainstay imaging modality in this war on cancer. Aims & Objectives: To assess the diagnostic accuracy of USG B-mode and doppler in characterisation of ovarian mass lesions. Methods: 103 women with ovarian lesions were evaluated with USG B-mode and doppler. The interpretation was compared with histopathology reports wherever possible. Results: With sensitivity and NPV of 81.82% and 84.62% of USG B-mode, it is a good primary imaging modality. By showing an increase in specificity to 94.23%, PPV to 89.29% and accuracy to 87.06%, the addition of doppler in the evaluation acts as a tool in confirmation of malignancy. Conclusion: With good diagnostic performance, USG proves to be a good primary imaging modality. Also, doppler evaluation forms a promising add-on that can be considered.

scholarly journals Role of FNAC in soft tissue tumors and its histopathological correlation

2017 ◽  
Vol 4 (8) ◽  
pp. 2632
Author(s):  
Veenu Jain ◽  
Tarun Agarwal
Keyword(s):  
Soft Tissue ◽  
Diagnostic Accuracy ◽  
Paraffin Section ◽  
Needle Aspiration ◽  
Soft Tissue Tumors ◽  
Age Group ◽  
Malignant Tumours ◽  
Soft Tissue Tumours ◽  
Histopathological Correlation ◽  
Benign Tumours

Background: Soft tissue tumours are very rare. They are diagnosed initially by Fine needle aspiration cytology (FNAC). The present study was conducted with the aim to study the acceptability and diagnostic accuracy of cytodiagnosis in soft tissue lesions, to evaluate the reliability of cytodianosis as compared conventional histological paraffin section and to assess nuclear grade in various soft tissue lesions.Methods: The present study was conducted on 140 patients of soft tissue tumours during the period from August 2002 to July 2003 in the Department of pathology and microbiology, LLRM medical college, Meerut. FNAC was done in 132 cases and histopathology was conducted in 86 cases and correlation of those results was done.Results: Diagnosis of STT by FNAC was done in 132 cases. In benign tumours maximum number of cases (28) was in the age group of 20-29 years and in malignant tumours maximum number of cases (7) was in the age group of 40-49 years. 110 (83.3%) cases were benign and 22 (16.7%) cases were found to be malignant. Maximum number of STT was observed in trunk followed by limb extremities. Male preponderance was observed in the study. The overall accuracy of the present study was 97.7%. Accuracy for diagnosing benign soft tissue tumours was 100% and for malignant STT was 94.5%. The sensitivity, specificity and predictive value of the present study was 100%, 98.6% and 93.3%.Conclusions: FNAC plays a very important role in initial diagnosis of soft tissue tumours. It provided acceptable diagnostic accuracy when supported by histopathology.

scholarly journals Comparison of 22G Standard and Franseen Needles in Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Diagnosing Pancreatic Mass Lesions: Study Protocol for a Controlled Trial

2019 ◽  
Author(s):  
Masahiro Itonaga ◽  
Satoru Yasukawa ◽  
Toshio Shimokawa ◽  
Mamoru Takenaka ◽  
Nobuyasu Fukutake ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Diagnostic Performance ◽  
Controlled Trial ◽  
Needle Aspiration ◽  
Pancreatic Mass ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Mass Lesions

Abstract Background Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) was developed with the aim of further improving the diagnostic performance of endoscopic ultrasound. Although novel puncture needles have been specifically designed for collecting sufficient tissue specimens, clinical studies have indicated no clear difference in diagnostic performance between these novel needles and conventional puncture needles. Recently, a needle with Franseen geometry was developed specifically for EUS-FNA biopsy. Due to the characteristic shape of its tip, the Franseen needle is expected to be effective for scraping tissues, thus potentially increasing the diagnostic accuracy of EUS-FNA biopsy. We plan to carry out a prospective, multicenter, open-labeled, controlled trial to compare conventional and Franseen needles in terms of the diagnostic accuracy of EUS-FNA for evaluating the malignancy of pancreatic mass lesions. Methods/design The study will enroll 520 patients with pancreatic mass managed at any of 21 participating endoscopic centers. Lesion samples obtained using 22G conventional and Franseen needles will be assessed to compare the efficacy and safety of these two types of needles in EUS-FNA for evaluating the malignancy of mass lesions in the pancreas. Tissue samples will be fixed in formalin and processed for histologic evaluation. For the purpose of this study, only samples obtained with the first needle pass will be used for comparing the: (i) accuracy of the malignancy diagnosis, (ii) sensitivity and specificity for the malignancy diagnosis, (iii) procedure completion rate, (iv) sample cellularity, and (v) incidence of complications. Discussion The outcomes of this study may provide insight into the optimal needle choice for evaluating the malignancy of pancreatic solid lesions, thus aiding in the development of practice guidelines for pancreatic diseases.

scholarly journals Diagnostic accuracy of fine needle aspiration cytology in thyroid swellings with histopathological correlation

2018 ◽  
Vol 5 (4) ◽  
pp. 1511
Author(s):  
Mahadeo R. Patil ◽  
Sandhyarani M. Patil
Keyword(s):  
Diagnostic Accuracy ◽  
Sensitivity And Specificity ◽  
High Specificity ◽  
Needle Aspiration ◽  
Histopathological Correlation ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology ◽  
Very High ◽  
Benign Thyroid ◽  
Rule Out

Background: Thyroid swellings are common in India. It is important to differentiate malignant from benign thyroid swellings for definitive planning of appropriate surgery. This study is undertaken to study sensitivity and specificity of FNAC in diagnosis of thyroid swellings by comparing preoperative FNAC with postoperative histopathology.Methods: A total of 156 patients with thyroid swellings were evaluated for a period of three years. Pre-operatively FNAC was done and was compared with post-operative histopathology and sensitivity and specificity of FNAC was studied.Results: Thyroid swellings are more common in females. In present study of 156 thyroid swellings, 90.38% cytologies were benign while 7.05% were malignant and 2.56% were suspicious for malignancy. Sensitivity of FNAC for malignant lesions was 93.75% and specificity was 100%.Conclusions: FNAC with its very high specificity, and diagnostic accuracy approaching 100% can help to rule out malignancy in most of thyroid swellings and prevent unnecessary surgeries.

scholarly journals Prospective evaluation of EUS-guided fine needle biopsy in pancreatic mass lesions

2018 ◽  
Vol 06 (02) ◽  
pp. E242-E248 ◽  
Author(s):  
M. Larsen ◽  
C. Fristrup ◽  
S. Detlefsen ◽  
M. Mortensen
Keyword(s):  
Diagnostic Accuracy ◽  
Prospective Study ◽  
Fine Needle Biopsy ◽  
Pancreatic Mass ◽  
Fine Needle ◽  
Technical Parameters ◽  
Microscopic Evaluation ◽  
Average Size ◽  
A Prospective Study ◽  
Mass Lesions

Abstract Background and study aim Due to the scarcity of specific data on endoscopic ultrasound (EUS)-guided fine-needle biopsies (SharkCore) FNB in the evaluation of pancreatic lesions, we performed a prospective study of the diagnostic performance of EUS SharkCore FNB in patients with pancreatic lesions. The aim of this study was to evaluate the diagnostic accuracy. Patients and methods Single-center prospective study of 41 consecutive patients referred for EUS-FNB from October 2015 to April 2016 at our center. EUS-FNB was obtained in a predefined setting regarding the procedure and pathological evaluation. Data regarding demographics, lesion, technical parameters, and diagnostic accuracy were obtained. Results The study included 41 consecutive patients (22 males (54 %); median age 68 years). The average size of the lesions was 28 mm (median: 30 mm). A diagnostic specimen was identified in 40 (98 %) cases during microscopy with an average of 2.4 passes. The route was trans-duodenal in 20 cases (49 %). The histological diagnosis of the specimens was malignant in 29 cases (71 %), benign in 8 (20 %), suspicious in 2 (5 %), atypical in 1 (2 %) and in 1 (2 %) no material for microscopic evaluation was obtained. This led to a diagnostic accuracy of 93 %, sensitivity of 91 % and a specificity of 100 %. 2 cases (5 %) of self-limiting bleeding were observed. The diagnosis at follow up was malignant in 32 (78 %) of the patients. Conclusions EUS-FNB of pancreatic mass lesions with the SharkCore needle produced specimens with a diagnostic accuracy of 93 %. The procedure was safe and easy to perform, and these data support the use of EUS-FNB in a routine setting.

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