Numerous psammoma bodies in cervical cytology of high-grade endocervical adenocarcinoma

Cytopathology ◽  
2013 ◽  
Vol 25 (4) ◽  
pp. 274-275
Author(s):  
T. Uehara ◽  
T. Kiyokawa ◽  
S. Tate ◽  
H. Usui ◽  
M. Shozu
2010 ◽  
Vol 118 (3) ◽  
pp. 146-156 ◽  
Author(s):  
Panduka Samarawardana ◽  
Donna L. Dehn ◽  
Meenakshi Singh ◽  
Douglas Franquemont ◽  
Chesney Thompson ◽  
...  

1994 ◽  
Vol 5 (5) ◽  
pp. 343-345 ◽  
Author(s):  
K A Ward ◽  
J R Houston ◽  
B E Lowry ◽  
R D Maw ◽  
W W Dinsmore

212 females attending a genitourinary medicine (GUM) clinic with first episode anogenital warts were screened by cervical cytology and colposcopy/histology for the presence of cervical epithelial abnormalities in keeping with infection by the human papillomavirus (HPV infection) and/or cervical intraepithelial neoplasia (CIN). The prevalence of cervical epithelial abnormalities detected by cervical cytology alone was 32%, rising to 56% after colposcopic examination. However, the majority of cervical lesions detected by colposcopy alone were of low grade (HPV infection and/or CIN I). Histologically confirmed high grade cervical lesions (CIN II or CIN III) were detected more frequently in those females in whom cervical cytological examination indicated dyskaryosis in keeping with any grade of CIN, compared to females without dyskaryotic changes on cervical smear ( P<0.05, chi-squared test with Yates' correction). Early colposcopy is indicated for females with anogenital warts in the presence of a cervical smear showing dyskaryosis in keeping with any grade of CIN, because of the statistically significant increased risk of detecting a potentially progressive high grade cervical lesion. In females without dyskaryotic changes on cervical smear, the value of early colposcopy is uncertain and warrants larger more long-term trials.


2019 ◽  
Vol 23 (1) ◽  
pp. 84 ◽  
Author(s):  
Pedro Vieira-Baptista ◽  
Joana Lyra ◽  
Catarina Melo ◽  
Filipa Almeida ◽  
Joana Lima-Silva
Keyword(s):  

Cytopathology ◽  
2020 ◽  
Vol 32 (1) ◽  
pp. 75-83
Author(s):  
Nancy Y. Greenland ◽  
Rebecca J. Wolsky ◽  
Teresa M. Darragh ◽  
Poonam Vohra

Cytopathology ◽  
2020 ◽  
Vol 31 (4) ◽  
pp. 288-291
Author(s):  
Ondrej Ondič ◽  
Jana Němcová ◽  
Reza Alaghehbandan ◽  
Kateřina Černá ◽  
Barbora Gomolčáková ◽  
...  

2020 ◽  
Vol 96 (6) ◽  
pp. 457-463 ◽  
Author(s):  
Brandon L Guthrie ◽  
Anne F Rositch ◽  
Joy Alison Cooper ◽  
Carey Farquhar ◽  
Rose Bosire ◽  
...  

ObjectiveHIV infection increases the risk of high-grade cervical neoplasia and invasive cervical carcinoma. The study addresses the limited data describing human papillomavirus (HPV) infection and cervical neoplasia among HIV-infected women in HIV-discordant relationships in sub-Saharan Africa, which is needed to inform screening strategies.MethodsA cross-sectional study of HIV-infected women with HIV-uninfected partners was conducted to determine the distribution of type-specific HPV infection and cervical cytology. This study was nested in a prospective cohort recruited between September 2007 and December 2009 in Nairobi, Kenya. Cervical cells for HPV DNA testing and conventional cervical cytology were collected. HPV types were detected and genotyped by Roche Linear Array PCR assay.ResultsAmong 283 women, the overall HPV prevalence was 62%, and 132 (47%) had ≥1 high-risk (HR)-HPV genotype. Of 268 women with cervical cytology results, 18 (7%) had high-grade cervical lesions or more severe by cytology, of whom 16 (89%) were HR-HPV-positive compared with 82 (41%) of 199 women with normal cytology (p<0.001). The most common HR-HPV types in women with a high-grade lesion or more severe by cytology were HPV-52 (44%), HPV-31 (22%), HPV-35 (22%), HPV-51 (22%) and HPV-58 (22%). HR-HPV genotypes HPV-16 or HPV-18 were found in 17% of women with high-grade lesions or more severe. HR-HPV screening applied in this population would detect 89% of those with a high-grade lesion or more severe, while 44% of women with normal or low-grade cytology would screen positive.ConclusionHR-HPV prevalence was high in this population of HIV-infected women with an uninfected partner. Choice of screening for all HR genotypes versus a subset of HR genotypes in these HIV-infected women will strongly affect the performance of an HPV screening strategy relative to cytological screening. Regional and subpopulation differences in HR-HPV genotype distributions could affect screening test performance.


2015 ◽  
Vol 19 (4) ◽  
pp. 329-332
Author(s):  
Sara E. Mazzoni ◽  
Sarah L. Bienenfeld ◽  
Mona B. Krull ◽  
Torri D. Metz ◽  
Meredith J. Alston
Keyword(s):  

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