Efficacy and safety of a soft contact lens to control myopia progression

2020 ◽  
Author(s):  
Alba M Garcia‐del Valle ◽  
Vanesa Blázquez ◽  
Juan Gros‐Otero ◽  
Mónica Infante ◽  
Antonio Culebras ◽  
...  
Keyword(s):  
Contact Lens ◽  
Efficacy And Safety ◽  
Soft Contact ◽  
Myopia Progression ◽  
Soft Contact Lens

scholarly journals Myopia Progression During Three Years of Soft Contact Lens Wear

2009 ◽  
Vol 86 (10) ◽  
pp. 1150-1153 ◽  
Author(s):  
Adam Blacker ◽  
G Lynn Mitchell ◽  
Mark A. Bullimore ◽  
Bill Long ◽  
Joseph T. Barr ◽  
...  
Keyword(s):  
Contact Lens ◽  
Soft Contact ◽  
Myopia Progression ◽  
Contact Lens Wear ◽  
Soft Contact Lens ◽  
Lens Wear

scholarly journals A 3-year Randomized Clinical Trial of MiSight Lenses for Slowing Myopia Progression

The Eye ◽  
2020 ◽  
Vol 22 (4(132)) ◽  
pp. 11-28
Author(s):  
P. Chamberlain ◽  
Sofia C. Peixoto-de-Matos ◽  
N. S. Logan ◽  
Ch. Ngo ◽  
D. Jones ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Contact Lens ◽  
Axial Length ◽  
Test Group ◽  
Control Group ◽  
Spherical Equivalent ◽  
Soft Contact ◽  
Myopia Progression ◽  
Soft Contact Lens ◽  
Spherical Equivalent Refraction

Significance. Results of this randomized, double-masked clinical trial demonstrate the effectiveness of the MiSight soft contact lens in slowing myopia progression over multiple years.Purpose. The purpose of this study was to quantify the effectiveness of MiSight daily disposable soft contact lens in slowing the progression of juvenile-onset myopia.Methods. Myopic children (spherical equivalent refraction, −0.75 to −4.00 D; astigmatism, < 1.00 D) aged 8 to 12 years with no prior contact lens experience were enrolled in a 3-year, double-masked, randomized clinical trial at four investigational sites in four countries. Subjects in each group were matched for age, sex, and ethnicity and were randomized to either a MiSight®1 day contact lens (test) or Proclear®1 day (control; omafilcon A) and worn on a daily disposable basis. Primary outcome measures were the change in cycloplegic spherical equivalent refraction and axial length.Results. Of the subjects enrolled, 75.5% (109/144) completed the clinical trial (53 test, 56 control). Unadjusted change in spherical equivalent refraction was −0.73 D (59%) less in the test group than in the control group (−0.51 ± 0.64 vs. –1.24 ± 0.61 D, P < 0.001). Mean change in axial length was 0.32 mm (52%) less in the test group than in the control group (0.30 ± 0.27 vs. 0.62 ± 0.30 mm, P < 0.001). Changes in spherical equivalent refraction and axial length were highly correlated (r = −0.90, P < .001). Over the course of the study, there were no cases of serious ocular adverse events reported. Four asymptomatic corneal infiltrative (one test, three control) events were observed at scheduled study visits.Conclusions. Results of this clinical trial demonstrate the effectiveness of the MiSight daily disposable soft contact lens in slowing change in spherical equivalent refraction and axial length.

scholarly journals Treatment of Rapid Progression of Myopia: Case Series and Literature Review

2021 ◽  
pp. 875-881
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Itay Lavy ◽  
Eran Pras ◽  
...  
Keyword(s):  
Contact Lens ◽  
Axial Length ◽  
Contact Lenses ◽  
Case Series ◽  
Rapid Progression ◽  
Retrospective Case ◽  
Soft Contact ◽  
Myopia Progression ◽  
Current Case ◽  
Soft Contact Lens

This retrospective case series demonstrates the combination of 0.05% atropine with MiSight<sup>®</sup> 1 day (Cooper vision, Sar Ramon, CA, USA) in rapid progression of myopia of 4 children. MiSight<sup>®</sup> 1 day is a peripheral defocus, center-distance soft contact lens and is effective at controlling moderate progression of myopia during the course of 1 year. The current case series included 2 females and 2 males with an average age of 9.68 ± 0.26 years and an average axial length of 24.81 ± 0.92 mm. Their myopic progression during the previous year was −1.45 ± 0.27 D. The children had not attempted any myopia control thus far. This relatively high increase prompted a combination treatment of daily instillation of 0.05% atropine and MiSight, a daily replacement soft contact lens. Cycloplegic refraction and a slit-lamp evaluation were performed every 6 months to confirm no adverse reactions or staining was present. The 8-item contact lens dry eye questionnaire (CLDEQ-8) score of these children was 10.66 ± 1.52. The average myopia progression at the end of 1 year decreased to −0.41 ± 0.11 D, and the average axial length increase was 0.28 ± 0.08 mm. To the best of the authors’ knowledge, this is the first published study showing a combination of 0.05% atropine and peripheral defocus soft contact lenses indicating efficacy at controlling moderate myopia progression.

Comparing the microflora of the conjunctiva and contact lens in therapeutic soft contact lens wearers

2020 ◽  
Vol 89 (6) ◽  
pp. 8-13
Author(s):  
T. A Veliksar ◽  
◽  
T. B. Gaidamaka ◽  
G. I. Drozhzhina ◽  
A. L. Molodaia ◽  
...  
Keyword(s):  
Contact Lens ◽  
Soft Contact ◽  
Soft Contact Lens
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