Visual signs and symptoms of corticobasal degeneration

Richard A Armstrong

doi:10.1111/cxo.12429

Neuropsychiatric Aspects in a Patient Diagnosed with Corticobasal Degeneration: Clinical Case of Low Incidence and Prevalence in Colombia

Case Reports in Neurology ◽

10.1159/000509073 ◽

2020 ◽

Vol 12 (3) ◽

pp. 387-401

Author(s):

Carlos Alberto Hurtado González ◽

Carolina Piedrahita ◽

Diana Vivas Álzate ◽

Juan José García Borrero ◽

Carlos Steven Marmolejo Escobar ◽

...

Keyword(s):

Verbal Memory ◽

Neuropsychiatric Symptoms ◽

Memory Loss ◽

Corticobasal Degeneration ◽

Lewy Body Dementia ◽

Signs And Symptoms ◽

Neurocognitive Deficits ◽

Low Incidence ◽

The Individual ◽

Gait Disturbances

Corticobasal degeneration (CBD) is a pathology of low incidence and prevalence worldwide; it is accompanied by symptoms such as dystonia, rigid akinetic syndrome (bradykinesia), gait disturbances, neurological deterioration associated with severe cortical subcortical atrophy, and progressive to moderate to severe neurocognitive deficits, especially in immediate verbal memory and dorsolateral or dysexecutive syndrome. We identified neurocognitive impairment and neuropsychiatric symptoms in a patient diagnosed with CBD. Participant was a 70-year-old female patient, single; she presented progressive memory loss of an immediate verbal nature. Initially, she was diagnosed with Alzheimer’s disease and Lewy body dementia, finding that she had no characteristic signs and symptoms of these pathologies. The patient presented conciliation insomnia, gait disturbances, and severe neurocognitive deficit, especially in executive functions, immediate verbal memory, and visuospatial functioning. It was found that the patient presented neurocognitive alterations of the executive type (frontal lobe) such as decision making, planning, inhibition and operative memory, correlated with a severe alteration in her basic, instrumental and advanced activities of daily life, with a high risk factor for developing dementia. It is necessary to diagnose in an assertive and timely manner in order to generate functional neurorehabilitation plans in people diagnosed with CBD, with the main objective of positively impacting quality of life, at the individual, family, and social level.

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“Where is Dementia?” A Systematic Literature Review Exploring Neuroanatomical Aspects of Dementia

Perspectives of the ASHA Special Interest Groups ◽

10.1044/persp2.sig15.9 ◽

2017 ◽

Vol 2 (15) ◽

pp. 9-23 ◽

Cited By ~ 1

Author(s):

Chorong Oh ◽

Leonard LaPointe

Keyword(s):

English Language ◽

Signs And Symptoms ◽

Behavioral Symptoms ◽

Journal Articles ◽

People With Dementia ◽

Different Types ◽

Precise Diagnosis ◽

Physical Changes ◽

The Brain ◽

Language Literature

Dementia is a condition caused by and associated with separate physical changes in the brain. The signs and symptoms of dementia are very similar across the diverse types, and it is difficult to diagnose the category by behavioral symptoms alone. Diagnostic criteria have relied on a constellation of signs and symptoms, but it is critical to understand the neuroanatomical differences among the dementias for a more precise diagnosis and subsequent management. With this regard, this review aims to explore the neuroanatomical aspects of dementia to better understand the nature of distinctive subtypes, signs, and symptoms. This is a review of English language literature published from 1996 to the present day of peer-reviewed academic and medical journal articles that report on older people with dementia. This review examines typical neuroanatomical aspects of dementia and reinforces the importance of a thorough understanding of the neuroanatomical characteristics of the different types of dementia and the differential diagnosis of them.

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