Dermal melanocytic tumor with CRTC1‐TRIM11 fusion: Report of two additional cases with review of the literature of an emerging entity

Author(s):  
Ourania Parra ◽  
Julia A. Bridge ◽  
Klaus J. Busam ◽  
Sara C. Shalin ◽  
Konstantinos Linos
2014 ◽  
Vol 41 (6) ◽  
pp. 529-535 ◽  
Author(s):  
Maria M. De la Garza Bravo ◽  
Jonathan L. Curry ◽  
Carlos A. Torres-Cabala ◽  
Doina S. Ivan ◽  
Carol Drucker ◽  
...  

2000 ◽  
Vol 32 (5) ◽  
pp. 240-247 ◽  
Author(s):  
H. Hakan Oruckaptan ◽  
Figen Soylemezoglu ◽  
Tezer Kutluk ◽  
Nejat Akalan

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Hany S. Hamza ◽  
Magdy Moussa ◽  
Abdelrahman M. Elhusseiny

Purpose. To report a rare case of melanocytoma associated choroidal neovascularization (CNV) treated with intravitreal aflibercept. Methods. We reviewed the literature for the previous reports and different methods of treatment. Results. Optic disc melanocytoma has been considered as a benign melanocytic tumor that rarely affects vision. There is evidence in the literature of association between choroidal neovascular membrane and disc melanocytoma. Conclusions. In conclusion, our article provides a review of literature of such a rare association in which the ophthalmologists must be aware of its occurrence and possible ways of management.


Biology ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1286
Author(s):  
Ourania Parra ◽  
Konstantinos Linos

“Cutaneous melanocytic tumor with CRTC1::TRIM11 fusion” (CMTCT) is a recently described entity belonging to the family of superficial tumors displaying melanocytic differentiation. Thirteen cases have been reported so far, on the head and neck, extremities, and trunk of adults of all ages (12 cases) and one in an 11-year-old child. Histopathologically, it is a nodular or multilobulated tumor composed of spindle and epithelioid cells arranged in nests, fascicles, or bundles that are surrounded by thin collagenous septa. By immunohistochemistry, the tumor shows variable immunoreactivity for S100-protein, SOX10, and MITF, as well as specific melanocytic markers such as MelanA and HMB-45. The neoplasm’s biologic behavior remains uncertain since the reported cases are limited and the follow-up is short (median 12 months). However, local recurrence and synchronous distant metastasis after 13 years of initial resection has been described in one case. Herein, we present a comprehensive literature review of CMTCT hoping to raise awareness among the dermatopathologists of this potentially novel entity.


2020 ◽  
Vol 5 (1) ◽  
pp. 326-338 ◽  
Author(s):  
Kristen Weidner ◽  
Joneen Lowman

Purpose We conducted a systematic review of the literature regarding adult telepractice services (screening, assessment, and treatment) from approximately 2014 to 2019. Method Thirty-one relevant studies were identified from a literature search, assessed for quality, and reported. Results Included studies illustrated feasibility, efficacy, diagnostic accuracy, and noninferiority of various speech-language pathology services across adult populations, including chronic aphasia, Parkinson's disease, dysphagia, and primary progressive aphasia. Technical aspects of the equipment and software used to deliver services were discussed. Some general themes were noted as areas for future research. Conclusion Overall, results of the review continue to support the use of telepractice as an appropriate service delivery model in speech-language pathology for adults. Strong research designs, including experimental control, across multiple well-described settings are still needed to definitively determine effectiveness of telepractice services.


1999 ◽  
Vol 19 (3) ◽  
pp. 328-335
Author(s):  
Shanop Shuangshoti Shuangshoti ◽  
Samruay Shuangshoti

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