Multicentric endocrine mucin‐producing sweat gland carcinoma and mucinous carcinoma of the skin: A case report

2020 ◽  
Vol 48 (1) ◽  
pp. 165-170
Author(s):  
Akana Nishimoto ◽  
Hiroaki Kuwahara ◽  
Ryuji Ohashi ◽  
Shin‐ichi Ansai
2010 ◽  
Vol 44 (1) ◽  
pp. 97 ◽  
Author(s):  
Sunhee Chang ◽  
Sang Hwa Shim ◽  
Mee Joo ◽  
Hanseong Kim ◽  
Yong Kyu Kim

Orthopedics ◽  
1988 ◽  
Vol 11 (8) ◽  
pp. 1189-1192
Author(s):  
Bruce M Leslie ◽  
John Kazes ◽  
Joseph D Ferrone

2020 ◽  
pp. 271-274
Author(s):  
Neera R. Nathan ◽  
Kevin S. Emerick ◽  
Mai P. Hoang ◽  
Gideon P. Smith ◽  
Molly Yancovitz

Dermatology ◽  
1988 ◽  
Vol 177 (5) ◽  
pp. 295-299 ◽  
Author(s):  
L. Borradori ◽  
R. Hertel ◽  
M. Balli-Antunes ◽  
L. Zala

Spine ◽  
1991 ◽  
Vol 16 (11) ◽  
pp. 1344-1346 ◽  
Author(s):  
YONEZO SAWADA ◽  
KOUICHI KANEKASU ◽  
YASUMITU TORIBATAKE ◽  
KAZUHIDE AIKI ◽  
SYUUHEI HAGIWARA ◽  
...  

2021 ◽  
pp. 014556132110167
Author(s):  
Zeliang Zhang ◽  
Shoucheng Yin ◽  
Zhongfei Xu ◽  
Shuai Wang

Introduction: The main aim of this article is to discuss and summarize the research advancements and the treatment methods for sweat gland carcinoma (SGC) based on 2 cases of SGC in our hospital and the related literature. Case Report: This article presents 2 patients with SGC who were treated in the China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases from 2007 to 2019. We analyzed the clinical features, therapies, and prognosis of the patients and searched for related literatures. Discussion: Two patients underwent extended resection for local lesions with no adjuvant radiotherapy. Neither local recurrence nor distant metastasis was detected during follow-up. Reviewing previous literature, the treatment of SGC includes surgical resection, radiotherapy, and chemotherapy. We have not found an effective treatment. The prognosis of SGC occurred in head and neck is relatively good compared with another primary-site location, primary surgical excision with safe resection margins and neck dissection is recommended.


2021 ◽  
Vol 26 ◽  
pp. 300551
Author(s):  
Chiemi Saigo ◽  
Yuki Hanamatsu ◽  
Masayoshi Hasegawa ◽  
Shusuke Nomura ◽  
Takuya Mikamo ◽  
...  

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S46-S46
Author(s):  
R Chiu ◽  
T Tran ◽  
M Miranda-Taylor ◽  
S Bamdad ◽  
Y Jia ◽  
...  

Abstract Introduction/Objective Sweat gland carcinomas are a group of malignant skin adnexal tumors that are difficult to diagnose due to their rarity, wide morphologic variation, and limited literature on diagnosis and classification. These tumors may appear bland and morphologically resemble benign skin adnexal tumors, or may appear poorly differentiated and mimic metastatic carcinoma especially from a breast primary. Biphasic sweat gland carcinomas are an even rarer entity, with only few cases reported in literature, and have been described to consist of a well- differentiated ductal epithelial component and a poorly differentiated, sarcomatoid, spindle cell component. Methods/Case Report Our case report describes a 53 year old female referred to our institution for diagnosis of an excised skin lesion of the right upper arm, which had been slowly growing for 8 years. The histology revealed a biphasic malignant neoplasm involving the dermis and subcutis. The tumor consisted of an epithelial cell component with glandular and squamoid morphology and positive for CK5/6, CK7, and CAM5.2, and a spindled myoepithelial cell component with sarcomatoid morphology and positive for S100, vimentin, and p63. Stains for CK20, ER, PR, PAX8, CEA, and TTF1 were negative. The histological and clinical findings favored a primary skin adnexal tumor, rather than a metastatic lesion. The patient underwent wide local excision of the lesion given that margins of the original excision were indeterminate. The histology of this re-excision demonstrated the same biphasic tumor with ductal epithelial and sarcomatoid myoepithelial cell components positive for the same stains. Although margins were negative in this re-excision, 3-4 months later, the patient developed dyspnea with multiple new pulmonary and hilar masses discovered on imaging, and new-onset headache with a frontal lobe mass discovered on brain imaging. These masses were biopsied/resected, and revealed to be metastases of the original cutaneous tumor positive for the same markers. Results (if a Case Study enter NA) NA Conclusion This case report describes a rare, diagnostically challenging case of a biphasic sweat gland carcinoma with ductal epithelial and sarcomatoid myoepithelial cell components, which demonstrated aggressive behavior with distant metastasis. These tumors are a clinicopathological quandary given their rarity and the paucity of literature on their characterization.


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