Cutaneous myxomas and a psammomatous melanotic schwannoma in a patient with Carney complex

2019 ◽  
Vol 46 (2) ◽  
pp. 93-96 ◽  
Author(s):  
Akua Sarfo ◽  
Klaus Helm ◽  
Alexandra Flamm
Haigan ◽  
2019 ◽  
Vol 59 (3) ◽  
pp. 244-247
Author(s):  
Kyoko Hijiya ◽  
Jin Sakamoto ◽  
Shinji Kosaka ◽  
Ren Nagasako

2018 ◽  
Vol 33 (6) ◽  
pp. 1256-1257
Author(s):  
Yea Eun Kang ◽  
Jin-Ok Jeong ◽  
Kyung-Hee Kim ◽  
Chang-Seok Ki ◽  
Hyun Jin Kim

2015 ◽  
Vol 58 (3) ◽  
pp. 368 ◽  
Author(s):  
Salapathi Shanmugam ◽  
Mitra Ghosh ◽  
Sadiya Niamathullah ◽  
Siddhartha Ghosh

2007 ◽  
Vol 6 (6) ◽  
pp. 591-599 ◽  
Author(s):  
Elisabetta Marton ◽  
Alberto Feletti ◽  
Enrico Orvieto ◽  
Pierluigi Longatti

✓The authors present the case of a dumbbell-shaped malignant psammomatous melanotic schwannoma of the upper cervical spine involving the C-2 sensory root. The family of the patient had a history of other malignant stromal tumors, without the Carney complex genetic pattern. The 30-year-old female patient complained of experiencing cervical pain and cervical muscle contractions for 6 months, and was admitted to the hospital. The cervical T1-weighted magnetic resonance (MR) images revealed the presence of a slightly hyperintense C2–3 intra–extradural lesion, moderately enhancing, which had eroded and enlarged the intervertebral foramen. The patient workup also included computed tomography scans and angiography. A posterior approach was used to perform a C2–3 hemilaminectomy, including opening of the dura mater and gross-total removal of the lesion. Histopathological examination of the lesion revealed it to be a malignant psammomatous melanotic schwannoma. The cerebrospinal MR image of the patient obtained at the 12-month follow-up examination demonstrated the presence of tumor progression into the subarachnoid space at the C-3 level. The strong malignancy potential of the lesion must be considered in the future management of the patient, especially due to the presence in the family of other stromal tumors such as gastrointestinalstromal tumors and malignant melanomas. The authors review all the literature concerning melanotic schwannomas and report 105 cases of melanotic schwannoma that were not related to the Carney complex. The particular focus of their review is on the characteristics of the malignant progression of melanotic schwannoma, such as local recurrences, metastasis, and survival rate.


2008 ◽  
Vol 86 (2) ◽  
pp. 657-660 ◽  
Author(s):  
Soeren Torge Mees ◽  
Tilmann Spieker ◽  
Elke Eltze ◽  
Jens Brockmann ◽  
Norbert Senninger ◽  
...  

2011 ◽  
Vol 2 (1) ◽  
pp. 136 ◽  
Author(s):  
ChristopherB Shields ◽  
StevenD Glassman ◽  
LisaB.E Shields ◽  
GeorgeH Raque

2015 ◽  
Vol 23 (2) ◽  
pp. 233-238 ◽  
Author(s):  
Saman Shabani ◽  
Susan M. Fiore ◽  
Roberta Seidman ◽  
Raphael P. Davis

The authors present a case of intraspinal malignant psammomatous melanotic schwannoma (PMS) not associated with Carney complex and review all reported cases not associated with this syndrome. The focus of this review paper is on the characteristics of the malignant progression of PMS. A 54-year-old man had a history of squamous cell carcinoma of the neck and tonsillar carcinoma. The patient’s serial CT scanning study showed a mass in the left C-5 foramen. On presentation he was neurologically intact. After 18 months, the patient developed radiating pain down the left arm with decreased sensation. MRI of the cervical spine showed an enhancing 2.1 × 1.5 × 1.9-cm mass in the left C5–6 foramen. A C5–6 hemilaminectomy was performed with gross-total removal of the tumor. At 3 months postoperatively, the patient developed new-onset pain and weakness. MRI showed a dumbbell-shaped mass in the left C-7 foramen. MRI of the pelvis showed a 1.4 × 1.0-cm lesion on the right ischium and a 1.1 × 2.8-cm lesion on the right inferior pubic ramus. Anterior cervical discectomy of C5–6 and C6–7 with corpectomy of C-6 with subtotal resection of the tumor was completed. PMS should not be considered a benign tumor because in 41.1% of patients, including the patient in this report, the tumor progresses to malignancy. Long-term follow-up is needed in these patients. New surgical treatment plans should be considered.


2006 ◽  
Vol 21 (6) ◽  
pp. 1-4 ◽  
Author(s):  
Ahmet Şengöz ◽  
Erol Taşdemiroğlu ◽  
Halit Togay

✓The authors present a case of clear cell sarcoma (CCS) in which the tumor originated in the S-1 nerve root and had been previously diagnosed as psammomatous melanotic schwannoma (PMS). This is the third case of a spinal nerve root origin for CCS reported in the English-language literature. The similar histogenesis of CCS and malignant melanoma supports the hypothesis that biological agents or immunotherapy are potentially important areas of investigation. The patient underwent S1–3 laminectomy and gross-total resection of the mass lesion. The border of the resection was extended 1 cm distal to the tumor margin. The postoperative period was uneventful. The new histopathological diagnosis was CCS (malignant melanoma of soft tissue). Despite total resection, the patient returned with disseminated disease at the 18-month follow-up visit. His follow-up magnetic resonance image of the lumbar spine revealed sacral L5–S3 involvement of the vertebral bodies along with disseminated cauda equina seeding. A CCS originating from peripheral nerves is quite rare. The histopathological and immunohistochemical appearance of CCSs resembles those of PMSs. Surgery should be the first choice of treatment.


2018 ◽  
Vol 116 ◽  
pp. 337-342 ◽  
Author(s):  
Galina I. Moisak ◽  
Dmitry E. Matsko ◽  
Sergey V. Chernov ◽  
Aleksandr B. Dmitriev ◽  
Mikhail E. Amelin ◽  
...  

1992 ◽  
Vol 20 (1) ◽  
pp. 71-73 ◽  
Author(s):  
C.M. THORNTON ◽  
J. HANDLEY ◽  
E.A. BINGHAM ◽  
P.G. TONER ◽  
M.Y. WALSH

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