Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma with KIR3DL2 and NKp46 expression in a human immunodeficiency virus carrier

2014 ◽  
Vol 42 (3) ◽  
pp. 199-205 ◽  
Author(s):  
Raymond Karkouche ◽  
Saskia Ingen-Housz-Oro ◽  
Sabine Le Gouvello ◽  
Frédéric Charlotte ◽  
Marina Thomas ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Cell Lymphoma ◽  
Cd8 T Cell ◽  
T Cell Lymphoma ◽  
Immunodeficiency Virus ◽  
Virus Carrier

scholarly journals Hemophagocytic Lymphohistiocytosis Complicating T-Cell Lymphoma in a Patient with HIV Infection

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Marc Uemura ◽  
Richard Huynh ◽  
Allen Kuo ◽  
Fernando Antelo ◽  
Robert Deiss ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Hiv Infection ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Poor Prognosis ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Diagnostic Specificity ◽  
Immunodeficiency Virus ◽  
Initiation Of Therapy

Hemophagocytic lymphohistiocytosis (HLH), while uncommon, may be a devastating complication of lymphoma and/or human immunodeficiency virus (HIV) infection. While several of the diagnostic criteria for HLH are relatively nonspecific, particularly in the setting of a systemic inflammatory response, more diagnostic specificity may be achieved with marked elevations in serum ferritin (e.g., >100,000 ng/mL). Increased suspicion of HLH, particularly in the setting of persistent, unexplained fevers, pancytopenia, and transaminitis, should prompt consideration of HLH. Earlier diagnosis and initiation of therapy have the potential to alter the natural history and poor prognosis of this disorder. We present a patient with HIV infection who developed relapsed T-cell lymphoma complicated by hemophagocytic lymphohistiocytosis.

Primary T-cell lymphoma of muscle in a patient infected with human immunodeficiency virus

1993 ◽  
Vol 95 (5) ◽  
pp. 545-546 ◽  
Author(s):  
George H. Lum ◽  
Thomas M. Cosgriff ◽  
Russell Byrne ◽  
Vishnu Reddy
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Immunodeficiency Virus

NK/T-Cell Lymphoma Associated with Epstein-Barr Virus in a Patient Infected with Human Immunodeficiency Virus: An Autopsy Case

2004 ◽  
Vol 79 (5) ◽  
pp. 480-483 ◽  
Author(s):  
Sang Cheul Oh ◽  
Chul Won Choi ◽  
Byung Soo Kim ◽  
Sang Won Shin ◽  
Yeul Hong Kim ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Epstein Barr Virus ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Autopsy Case ◽  
Barr Virus ◽  
Immunodeficiency Virus ◽  
Nk T Cell ◽  
Epstein Barr

scholarly journals Epstein-Barr virus-related oral T-cell lymphoma associated with human immunodeficiency virus immunosuppression

Blood ◽  
1993 ◽  
Vol 81 (12) ◽  
pp. 3350-3356 ◽  
Author(s):  
JA Thomas ◽  
F Cotter ◽  
AM Hanby ◽  
LQ Long ◽  
PR Morgan ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Epstein Barr Virus ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Barr Virus ◽  
Ebv Infection ◽  
Hairy Leukoplakia ◽  
Immunodeficiency Virus ◽  
Epstein Barr

Epstein-Barr virus (EBV) is generally held to infect B cells and epithelial cells, although there are now reports of EBV infection in normal T cells and neoplastic T-cell diseases. In patients with human immunodeficiency virus (HIV) infection, EBV is associated with the benign epithelial lesion, hairy leukoplakia, and has been reported in up to 80% of acquired immunodeficiency syndrome (AIDS)-related B-cell lymphoma. This study shows the presence of EBV in malignant oral T-cell lymphoma in three AIDS patients, two of whom had concurrent manifestation of hairy leukoplakia. The T-cell lineage of the tumor cells was determined by positive immunophenotyping for T-cell markers and lack of B-cell or nonhematopoietic (cytokeratin) determinants. All tumors contained monoclonal T-cell populations shown by polymerase chain reaction, which showed amplification of T-cell receptor gamma chain DNA without evidence of Ig heavy chain gene rearrangement. Furthermore, these lesions showed the presence of EBV DNA and expression of EBV latent gene products in the tumor cells. EBV involvement in AIDS-related T-cell lymphoma has not been widely reported and may represent a further manifestation of opportunistic EBV infection arising in the HIV-immunocompromised host.

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