scholarly journals Preoperative medication use and development of postoperative delirium and cognitive dysfunction

2021 ◽  
Author(s):  
Maria Heinrich ◽  
Anja Nottbrock ◽  
Friedrich Borchers ◽  
Rudolf Mörgeli ◽  
Jochen Kruppa ◽  
...  
Keyword(s):  
Cognitive Dysfunction ◽  
Postoperative Delirium ◽  
Medication Use ◽  
Preoperative Medication

scholarly journals Preoperative medication use and postoperative delirium: a systematic review

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Gizat M. Kassie ◽  
Tuan A. Nguyen ◽  
Lisa M. Kalisch Ellett ◽  
Nicole L. Pratt ◽  
Elizabeth E. Roughead
Keyword(s):  
Systematic Review ◽  
Postoperative Delirium ◽  
Medication Use ◽  
Preoperative Medication

Do Risk Prediction Models for Postoperative Delirium Consider Patients’ Preoperative Medication Use?

Drugs & Aging ◽  
2018 ◽  
Vol 35 (3) ◽  
pp. 213-222 ◽  
Author(s):  
Gizat M. Kassie ◽  
Tuan A. Nguyen ◽  
Lisa M. Kalisch Ellett ◽  
Nicole L. Pratt ◽  
Elizabeth E. Roughead
Keyword(s):  
Risk Prediction ◽  
Postoperative Delirium ◽  
Prediction Models ◽  
Medication Use ◽  
Risk Prediction Models ◽  
Preoperative Medication

Postoperative Delirium is Associated with Postoperative Cognitive Dysfunction at One Week after Cardiac Surgery with Cardiopulmonary Bypass

2009 ◽  
Vol 105 (3) ◽  
pp. 921-932 ◽  
Author(s):  
Judith A. Hudetz ◽  
Alison J. Byrne ◽  
Kathleen M. Patterson ◽  
Paul S. Pagel ◽  
David C. Warltier
Keyword(s):  
Cardiac Surgery ◽  
Intensive Care ◽  
Cognitive Impairment ◽  
Cardiopulmonary Bypass ◽  
Cognitive Dysfunction ◽  
Postoperative Delirium ◽  
Postoperative Cognitive Dysfunction ◽  
Surgical Patients ◽  
Nonverbal Memory ◽  
Surgery Group

Postoperative delirium with cognitive impairment frequently occurs after cardiac surgery. It was hypothesized that delirium is associated with residual postoperative cognitive dysfunction in patients after surgery using cardiopulmonary bypass. Male cardiac surgical patients ( M age = 66 yr., SD = 8; M education = 13 yr., SD = 2) and nonsurgical controls ( M age = 62, SD = 7; M education = 12, SD = 2) 55 years of age or older were balanced on age and education. Delirium was assessed by the Intensive Care Delirium Screening Checklist preoperatively and for up to 5 days postoperatively. Recent verbal and nonverbal memory and executive functions were assessed (as scores on particular tests) before and 1 wk. after surgery. In 56 patients studied ( n = 28 Surgery; n=28 Nonsurgery), nine patients from the Surgery group developed delirium. In the Surgery group, the proportion of patients having postoperative cognitive dysfunction was significantly greater in those who experienced delirium (89%) compared with those who did not (37%). The odds of developing this dysfunction in patients with delirium were 14 times greater than those who did not. Postoperative delirium is associated with scores for residual postoperative cognitive dysfunction 1 wk. after cardiac surgery.

scholarly journals Biomarkers of postoperative delirium and cognitive dysfunction

2015 ◽  
Vol 7 ◽  
Author(s):  
Ganna Androsova ◽  
Roland Krause ◽  
Georg Winterer ◽  
Reinhard Schneider
Keyword(s):  
Cognitive Dysfunction ◽  
Postoperative Delirium

Presurgical cognitive impairment is associated with postoperative delirium and postoperative cognitive dysfunction

2020 ◽  
Vol 86 (4) ◽  
Author(s):  
Cornelia Knaak ◽  
Wolf-Rüdiger Brockhaus ◽  
Claudia Spies ◽  
Friedrich Borchers ◽  
Sophie K. Piper ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Dysfunction ◽  
Postoperative Delirium ◽  
Postoperative Cognitive Dysfunction

Pharmacologic Considerations in the Elderly Surgical Patient

2016 ◽  
Author(s):  
Linda Sohn ◽  
Joe C. Hong ◽  
Michael W. Yeh ◽  
Tara A. Russell ◽  
Marcia M. Russell
Keyword(s):  
Older Adults ◽  
Surgical Procedures ◽  
Postoperative Delirium ◽  
Medication Management ◽  
The Elderly ◽  
The United States ◽  
Surgical Patient ◽  
Age Related ◽  
The Impact ◽  
Preoperative Medication

The most rapidly growing segment of the elderly population corresponds to persons age 85 and over. As of 2006, elderly patients accounted for 35.3% of the inpatient and 32.1% of the outpatient surgical procedures occurring in the United States. Because age-related changes occur in each organ system in all elderly individuals, this population merits special consideration when undergoing surgical procedures. Furthermore, there is a high probability that older adults will have multiple chronic medical problems, which may present a complex medication management challenge. This review covers the pharmacologic impact of physiologic changes associated with aging, preoperative assessment, preoperative medication management, delirium and the impact of perioperative medications in the elderly, anesthesia and related medications, and specific drug classes and their use in the elderly surgical patient. Figures show an overview of the management of the elderly surgical patient, and preoperative medication management. Tables list medications that should be avoided in older patients with reduced renal function, drugs that exhibit additive adverse effects, medications with high anticholinergic activity, medications that inhibit and induce the CYP450 system, herbal supplements, 2015 Beers Criteria summary of potentially inappropriate medication use in older adults, drugs associated with postoperative delirium, risk factors for postoperative delirium, and clinical pharmacology of commonly used anesthetic agents.   This review contains 2 highly rendered figures, 9 tables, and 61 references

Physostigmine for prevention of postoperative delirium and long-term cognitive dysfunction in liver surgery

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Claudia D. Spies ◽  
Cornelia Knaak ◽  
Mandy Mertens ◽  
Wolf-Rüdiger Brockhaus ◽  
Anna Shadenok ◽  
...  
Keyword(s):  
Cognitive Dysfunction ◽  
Liver Surgery ◽  
Postoperative Delirium
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