Airway complications in lung transplant recipients with telomere‐related interstitial lung disease

2021 ◽  
Author(s):  
Bina Choi ◽  
Jonathan Messika ◽  
Andrew Courtwright ◽  
Jean François Mornex ◽  
Sandrine Hirschi ◽  
...  
Keyword(s):  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Airway Complications ◽  
Lung Transplant Recipients

scholarly journals Longitudinal assessment of interstitial lung disease in single lung transplant recipients with scleroderma

Rheumatology ◽  
2019 ◽  
Vol 59 (4) ◽  
pp. 790-798
Author(s):  
Alicia M Hinze ◽  
Cheng T Lin ◽  
Amira F Hussien ◽  
Jamie Perin ◽  
Aida Venado ◽  
...  
Keyword(s):  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Longitudinal Assessment ◽  
Hounsfield Units ◽  
Lung Density ◽  
Native Lung ◽  
Single Lung Transplant ◽  
Lung Transplant Recipients

Abstract Objective To investigate the natural history of fibrotic lung disease in recipients of a single lung transplant for scleroderma-associated interstitial lung disease (ILD). Methods Global ILD (including ground glass, nodular opacities and fibrosis) was categorized into severity quintiles on first and last post-transplant CT scans, and percent fibrosis by manual contouring was also determined, in nine single lung transplant recipients. Quantitative mean lung densities and volumes for the native and allograft lungs were also acquired. Results In the native lung, global ILD severity quintile worsened in two cases and percent fibrosis worsened in four cases (range 5–28%). In the lung allograft, one case each developed mild, moderate and severe ILD; of these, new fibrotic ILD (involving <10% of lung) occurred in two cases and acute cellular rejection occurred in one. The average change in native lung density over time was +2.2 Hounsfield Units per year and lung volume +1.4 ml per year, whereas the allograft lung density changed by –5.5 Hounsfield Units per year and total volume +27 ml per year (P = 0.011 and P = 0.039 for native vs allograft density and volume comparisons, respectively). Conclusions While the course of ILD in the native and transplanted lungs varied in this series, these cases illustrate that disease progression is common in the native lung, suggesting that either the immune process continues to target autoantigens or ongoing fibrotic pathways are active in the native lung. Mild lung disease may occur in the allograft after several years due to either allograft rejection or recurrent mild ILD.

scholarly journals COPA SYNDROME-ASSOCIATED MUTATIONS IN LUNG TRANSPLANT RECIPIENTS FOR INTERSTITIAL LUNG DISEASE

CHEST Journal ◽  
2021 ◽  
Vol 160 (4) ◽  
pp. A1265-A1266
Author(s):  
Sarah Beshay ◽  
Jessica Smith ◽  
Isabella Osuna ◽  
Justin Branch ◽  
Laura Muruato ◽  
...  
Keyword(s):  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Lung Transplant Recipients ◽  
Copa Syndrome

scholarly journals Impact of Cold Ischemia Time on Frequency of Airway Complications Among Lung Transplant Recipients

2020 ◽  
Vol 52 (7) ◽  
pp. 2160-2164
Author(s):  
Mirosław Nęcki ◽  
Remigiusz Antończyk ◽  
Anastazja Pandel ◽  
Martyna Gawęda ◽  
Magdalena Latos ◽  
...  
Keyword(s):  
Lung Transplant ◽  
Cold Ischemia Time ◽  
Transplant Recipients ◽  
Cold Ischemia ◽  
Ischemia Time ◽  
Airway Complications ◽  
Lung Transplant Recipients

Ultraflex stents for the management of airway complications in lung transplant recipients

Respirology ◽  
2003 ◽  
Vol 8 (1) ◽  
pp. 59-64 ◽  
Author(s):  
Prashant N. CHHAJED ◽  
Monique A. MALOUF ◽  
Michael TAMM ◽  
Allan R. GLANVILLE
Keyword(s):  
Lung Transplant ◽  
Transplant Recipients ◽  
Airway Complications ◽  
Lung Transplant Recipients

scholarly journals Large Airway Complications in 150 Consecutive Lung Transplant Recipients

2008 ◽  
Vol 15 (3) ◽  
pp. 152-157 ◽  
Author(s):  
David B. Erasmus ◽  
Cesar A. Keller ◽  
Francisco B. Alvarez
Keyword(s):  
Lung Transplant ◽  
Transplant Recipients ◽  
Airway Complications ◽  
Large Airway ◽  
Lung Transplant Recipients
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