Outcomes and Resource Use for Liver Transplantation in the US: Insights from the 2009‐2017 National Inpatient Sample

2021 ◽  
Author(s):  
Esteban Aguayo ◽  
Joseph Hadaya ◽  
Morcos Nakhla ◽  
Catherine G. Williamson ◽  
Vishal Dobaria ◽  
...  
2019 ◽  
Vol 44 (7) ◽  
pp. 766-772 ◽  
Author(s):  
V. Singam ◽  
S. Rastogi ◽  
K. R. Patel ◽  
H. H. Lee ◽  
J. I. Silverberg

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
L Wu ◽  
K Ho

Abstract Introduction/Background In recent years, the percutaneous left atrial appendage closure (LAAC) has been gaining its popularity in the US. However its use in the US in recent years has not been well described. Purpose To provide an updated cross-sectional survey of performance of percutaneous LAAC in the US at national database level. Methods We use ICD-10 disease and procedure code to identify all the percutaneous LAAC performed in 2016 in US from national inpatient sample database. The demographic feature, comorbidity, mean time to procedure, mortality, complication rate, length of stay, total cost were described. Procedure related complication Including any vascular, cardiac, respiratory, neurologic and renal complications defined by AHRQ as patient safety indicators. Results There is approximately a total of 7550 percutaneous LAAC performed in the US in 2016. The majority of the patients were elderly (mean age 66.83±0.34), white (80.41%) male (59.04%). The mean Charlson Comorbidity Index score is 1.74, with hypertension (76.75%), diabetes (29.23%) being the most common comorbidity. The mean time to procedure is 1.98±0.11 days. The procedure related mortality is 2.06%, whereas the complication rate is 19.6%. The average length of stay is 10.77 day, with an average total cost of 239.67 thousand dollars. Baseline characterlistisc and outcomes Total percutaneous LAAC (estimated from sample) 7550 Age, years 66.83±0.34 Male, % 59.04 White, % 80.41 Mean Charlson Comorbidity Index 1.74±0.31 Hypertension, % 76.75 Diabetes, % 29.23 CKD, % 21.42 Mean Time to procedure, days 1.98±0.11 Mortality, % 2.06 Length of Stay, days 10.77±0.25 Any Complication, % 19.6 Total Cost, thousand dollars 239.67±10.01 Values are reported as mean ± SD. Categorical variables are represented as frequency. Conclusion A total of 7550 percutaneous LAAC was performed in US in 2016. The procedure related mortality is 2.06%, with an average time to procedure of 1.98 days and a length of stay of 10.77 days.


2013 ◽  
Vol 04 (01) ◽  
pp. 8-19
Author(s):  
Justin Weinheimer ◽  
Erin Wheeler-Cook ◽  
Don Ethridge ◽  
Darren Hudson

2017 ◽  
Vol 37 (suppl_1) ◽  
Author(s):  
Samson E Alliu ◽  
Adeyinka Adejumo ◽  
Modupeolowa Durojaiye ◽  
Oluwole Adegbala ◽  
Tokunbo Ajayi ◽  
...  

Background: With increasing legalization of cannabis, there is a growing number of cannabis users in the US. Cannabidiol - a component of cannabis with no psychoactive or cognitive effect has been proven in animal models to have vasodilatory and anti-inflammatory effect on the blood vessels. However, in clinical literature, the association between cerebrovascular accident (CVA) and cannabis remains inconclusive. Objective: To examine if there is a difference in the prevalence of CVA among patients who use cannabis and non-users. Methods: We identified patients > 18 years (N=12,114,360) from the 2012 -2014 National Inpatient Sample database. Using the ICD-9 code, we categorized patients using cannabis (non-dependent and dependent users) and non-users. Our outcome of interest was prevalence of CVA in this population. Logistic regression analysis was performed to assess the association between cannabis use and CVA. Using multivariate regression model, we adjusted for known confounders of CVA; age, gender, race, insurance type, socioeconomic status, tobacco use, cocaine use, alcohol abuse, amphetamine use, hyperlipidemia, diabetes, hypertension, renal failure, prior history of CVA and family history of CVA. Results: From our study sample (12,114,360 hospitalized patients), 2.1% (253,752) had a diagnosis of CVA, 1.48% (179,576) were non-dependent cannabis users and 0.21% (25,968) dependent users. Among hospitalized patient, non-dependent cannabis use was associated with an 8% increased odds of CVA (AOR 1.08 [1.03-1.13]) compared to non-users. However, dependent cannabis use was associated with a 60% decreased odds of CVA (AOR 0.40 [0.31-0.49]) compared to non-users. Also, In-group comparison shows a 60% decreased odds of CVA among dependent cannabis users (AOR 0.36[0.29-0.46]) compared to non-dependent cannabis users. Conclusions: Non-dependent cannabis use was associated with a slightly increased odd of CVA while dependent cannabis use was independently protective against CVA. Our study used the largest repository of clinical information to explore this association, however we recommend more clinical study to explore this correlation in other to maximize the pharmacological benefit of cannabidiol in cannabis for the prevention of CVA.


Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Philip R Khoury ◽  
Jane C Khoury

Due to the obesity epidemic in the US Population, there has been a related increase in type 2 diabetes. We sought to examine the trend within patients hospitalized due to stroke in a representative population. Methods: Using data from 1998 through 2011 from the National Inpatient Sample (NIS), we aimed to see the trends in diabetes for patients hospitalized with a primary discharge diagnosis of stroke (SAH (ICD code 430), ICH (ICD codes 431 and 432.9) and Ischemic (ICD codes 433x1, 434.11and 434.91). Secondary ICD codes were used to define diabetes. Hospitalizations used in this analysis included patients aged 20 years and over at date of admission. Results: For the 14 years examined, there were a total of 1,360,839 records with primary diagnosis of stroke, distributed as; 5.4% SAH, 15% ICH, and 79.6% Ischemic. The sample was 46% male; and 29% had diabetes (93% type 2). The rate of diabetes for each stroke subtype was: 12.2% SAH, 22.2% of ICH, and 31.5% of Ischemic. The proportion of stroke discharges with diabetes showed a significant increase with time, with a year over year increase in 12 of the 13 periods, from 26.5 in 1998 to 30.0 in 2011. Conclusions: The proportion of patients hospitalized for stroke who had comorbid diabetes continue to increase year over year, with almost one third of patients hospitalized for Ischemic stroke also having diabetes in 2011. This suggests that control of diabetes, and associated reduction of obesity may lead to reduction of stroke in the US.


Author(s):  
Nilay Kumar ◽  
Anand Venkatraman ◽  
Neetika Garg

Background and objectives: There are limited data on racial differences in clinical and economic outcomes of acute ischemic stroke (AIS) hospitalizations in the US. We sought to ascertain the effect of race on AIS outcomes in a population based retrospective cohort study. Methods: We used the 2012 National Inpatient Sample (NIS), which is the largest database of inpatient stays in the US, to identify cases of AIS using ICD9-CM codes 433.01, 433.11, 433.21, 433.31, 433.81, 433.91, 434.01, 434.11, 434.91 and 437.1 in patients >=18 years of age. Cases with missing data on race were excluded (5% of study sample). Primary outcome was in-hospital mortality. Secondary outcomes included proportion receiving endovascular mechanical thrombectomy (EMT) or thrombolysis, mean inflation adjusted charges and length of stay. Linear and logistic regression was used to test differences in continuous and categorical outcomes respectively. Survey techniques were used for all analyses. Results: There were 452, 330 hospitalizations for AIS in patients >=18 years in 2012. In univariate logistic regression using race as predictor, in-hospital mortality was significantly lower for Blacks (p<0.001), Hispanics (p=0.025) and Native Americans (p=0.047) compared to Whites. However, after adjusting for age, sex, Charlson comorbidity index, EMT and thrombolysis only blacks had a significantly lower mortality compared to whites (OR 0.74, 95% CI 0.66 - 0.82, p<0.001). Black patients were less likely to receive thrombolysis (OR 0.87, 95% CI 0.79 - 0.95; p=0.003) whereas Asian or Pacific Islanders were more likely to receive thrombolysis (OR 1.20, 95% CI 1.01 - 1.44; p=0.043) compared to whites. There was no difference in rates of EMT by race (p=0.18). Total charges and length of stay were significantly higher in racial minorities compared to whites (table). Conclusions: Blacks hospitalized for AIS have significantly lower in-hospital mortality compared to whites but are significantly less likely to receive thrombolysis compared to whites. Total charges and length of stay are significantly higher for racial minorities. Future studies should investigate mechanisms of this apparent protective effect of black race on in-hospital mortality in AIS.


Sign in / Sign up

Export Citation Format

Share Document