Multiorgan procurement is associated with a survival benefit after heart transplantation

2020 ◽  
Vol 34 (8) ◽  
Author(s):  
Jonathan Trent Magruder ◽  
Yoshikazu Suzuki ◽  
Alexandra Sperry ◽  
Charles R. Vasquez ◽  
Benjamin Smood ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Survival Benefit ◽  
Multiorgan Procurement

Cardiac Allocation Score: A Survival-Benefit Model for Heart Transplantation

2018 ◽  
Vol 37 (4) ◽  
pp. S181
Author(s):  
E.Z. Xing ◽  
S.G. Margelis ◽  
P.L. Karas ◽  
S. Emmanuel ◽  
Y.S. Kim ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Survival Benefit

scholarly journals Survival Benefit From Transplantation in Patients Listed for Heart Transplantation in the United States

2014 ◽  
Vol 63 (12) ◽  
pp. 1169-1178 ◽  
Author(s):  
Tajinder P. Singh ◽  
Carly E. Milliren ◽  
Christopher S. Almond ◽  
Dionne Graham
Keyword(s):  
United States ◽  
Heart Transplantation ◽  
Survival Benefit ◽  
The United States

Survival benefit of heart transplantation in high risk donors and recipients

2003 ◽  
Vol 22 (1) ◽  
pp. S163-S164 ◽  
Author(s):  
H Luckraz ◽  
S.C Charman ◽  
L Sharples ◽  
J Wallwork ◽  
J Parameshwar ◽  
...  
Keyword(s):  
High Risk ◽  
Heart Transplantation ◽  
Survival Benefit

Decline of increased risk donor offers increases waitlist mortality in paediatric heart transplantation

2021 ◽  
pp. 1-10
Author(s):  
Jordan E. Ezekian ◽  
Michael S. Mulvihill ◽  
Brian Ezekian ◽  
Morgan L. Cox ◽  
Sonya Kirmani ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Disease Transmission ◽  
Survival Benefit ◽  
Cox Regression ◽  
Infectious Disease Transmission ◽  
Competing Risks Analysis ◽  
Increased Risk ◽  
Risk Of Disease ◽  
Waitlist Mortality

Abstract Background: Increased risk donors in paediatric heart transplantation have characteristics that may increase the risk of infectious disease transmission despite negative serologic testing. However, the risk of disease transmission is low, and refusing an IRD offer may increase waitlist mortality. We sought to determine the risks of declining an initial IRD organ offer. Methods and results: We performed a retrospective analysis of candidates waitlisted for isolated PHT using 20072017 United Network of Organ Sharing datasets. Match runs identified candidates receiving IRD offers. Competing risks analysis was used to determine mortality risk for those that declined an initial IRD offer with stratified Cox regression to estimate the survival benefit associated with accepting initial IRD offers. Overall, 238/1067 (22.3%) initial IRD offers were accepted. Candidates accepting an IRD offer were younger (7.2 versus 9.8 years, p < 0.001), more often female (50 versus 41%, p = 0.021), more often listed status 1A (75.6 versus 61.9%, p < 0.001), and less likely to require mechanical bridge to PHT (16% versus 23%, p = 0.036). At 1- and 5-year follow-up, cumulative mortality was significantly lower for candidates who accepted compared to those that declined (6% versus 13% 1-year mortality and 15% versus 25% 5-year mortality, p = 0.0033). Decline of an IRD offer was associated with an adjusted hazard ratio for mortality of 1.87 (95% CI 1.24, 2.81, p < 0.003). Conclusions: IRD organ acceptance is associated with a substantial survival benefit. Increasing acceptance of IRD organs may provide a targetable opportunity to decrease waitlist mortality in PHT.

Candidate Selection and the Survival Benefit of Heart Transplantation in the United States

2019 ◽  
Vol 38 (4) ◽  
pp. S185
Author(s):  
W.F. Parker ◽  
E.S. Huang ◽  
R.D. Gibbons ◽  
A.S. Anderson ◽  
M.M. Churpek
Keyword(s):  
United States ◽  
Heart Transplantation ◽  
Survival Benefit ◽  
The United States ◽  
Candidate Selection

Impact of Multiorgan Procurement on Survival Following Heart Transplantation

2020 ◽  
Vol 39 (4) ◽  
pp. S266-S267
Author(s):  
J. Magruder ◽  
A. Sperry ◽  
C.R. Vasquez ◽  
B.F. Smood ◽  
J.C. Grimm ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Multiorgan Procurement
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