CT volumetry is superior to nuclear renography for prediction of residual kidney function in living donors

2016 ◽  
Vol 30 (9) ◽  
pp. 1028-1035 ◽  
Author(s):  
Andrew S. Barbas ◽  
Yanhong Li ◽  
Murtuza Zair ◽  
Julie A. Van ◽  
Olusegun Famure ◽  
...  
2017 ◽  
Vol 16 (3) ◽  
pp. e1764
Author(s):  
R. Lynnette ◽  
Y. Goh ◽  
B.C. Tai ◽  
L. Raman ◽  
A. Vathsala ◽  
...  

2018 ◽  
Vol 9 (2) ◽  
pp. 69-82 ◽  
Author(s):  
Inkyong Hur ◽  
Yong Kyu Lee ◽  
Kamyar Kalantar-Zadeh ◽  
Yoshitsugu Obi

Background: Residual kidney function (RKF) is often expected to inevitably and rapidly decline among hemodialysis patients and, hence, has been inadvertently ignored in clinical practice. The importance of RKF has been revisited in some recent studies. Given that patients with end-stage renal disease now tend to initiate maintenance hemodialysis therapy with higher RKF levels, there seem to be important opportunities for incremental hemo­dialysis by individualizing the dose and frequency according to their RKF levels. This approach is realigned with precision medicine and patient-centeredness. Summary: In this article, we first review the available methods to estimate RKF among hemodialysis patients. We then discuss the importance of maintaining and monitoring RKF levels based on a variety of clinical aspects, including volume overload, blood pressure control, mineral and bone metabolism, nutrition, and patient survival. We also review several potential measures to protect RKF: the use of high-flux and biocompatible membranes, the use of ultrapure dialysate, the incorporation of hemodiafiltration, incremental hemodialysis, and a low-protein diet, as well as general care such as avoiding nephrotoxic events, maintaining appropriate blood pressure, and better control of mineral and bone disorder parameters. Key Message: Individualized hemodialysis regimens may maintain RKF, lead to a better quality of life without compromising long-term survival, and ensure precision medicine and patient-centeredness in nephrology practice.


2019 ◽  
Vol 39 (2) ◽  
pp. 147-154 ◽  
Author(s):  
Yasuhiro Kawai ◽  
Shigeru Tanaka ◽  
Hisako Yoshida ◽  
Masatoshi Hara ◽  
Hiroaki Tsujikawa ◽  
...  

Background Residual kidney function (RKF) is an important factor influencing both technique and patient survival in peritoneal dialysis (PD) patients. B-type natriuretic peptide (BNP) is considered a marker of cardio-renal syndrome. The relationship between BNP and RKF in PD patients remains unclear. Methods We conducted a prospective study of 89 patients who had started and continued PD for 6 months or more in Kyushu University Hospital between June 2006 and September 2015. Participants were divided into low BNP (≤ 102.1 ng/L) and high BNP (> 102.1 ng/L) groups according to median plasma BNP level at PD initiation. The primary outcome was RKF loss, defined as 24-hour urine volume less than 100 mL. We estimated the association between BNP and RKF loss using a Kaplan-Meier method and Cox proportional hazards model and compared the rate of RKF decline between the 2 groups. To evaluate the consistency of the association, we performed subgroup analysis stratified by baseline characteristics. Results During the median follow-up of 30 months, 30 patients lost RKF. Participants in the high BNP group had a 5.87-fold increased risk for RKF loss compared with the low BNP group after adjustment for clinical and cardiac parameters. A high plasma BNP level was more clearly associated with RKF loss in younger participants compared with older participants in subgroup analysis. Conclusions B-type natriuretic peptide may be a useful risk marker for RKF loss in PD patients. The clinical importance of plasma BNP level as a marker of RKF loss might be affected by age.


1990 ◽  
Vol 22 (6) ◽  
pp. 573-579 ◽  
Author(s):  
O. Schück ◽  
J. Erben ◽  
H. Nádvorníková ◽  
V. Teplan ◽  
O. Marečková ◽  
...  

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Joshua J. Augustine ◽  
Susana Arrigain ◽  
Didier A. Mandelbrot ◽  
Jesse D. Schold ◽  
Emilio D. Poggio

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