Central retinal artery occlusion, an early sign of crizotinib resistance in an alk positive adenocarcinoma of lung: A rare case report

2016 ◽  
Vol 12 (2) ◽  
pp. 806-810 ◽  
Author(s):  
Irappa Madabhavi ◽  
Apurva Patel ◽  
Asha Anand ◽  
Harsha Panchal ◽  
Sonia Parikh
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Central Retinal Artery Occlusion ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Central Retinal Artery ◽  
Adenocarcinoma Of Lung ◽  
Rare Case Report ◽  
Retinal Artery ◽  
Alk Positive

scholarly journals Central retinal artery and vein occlusion as a complication of persistent hyaloid artery – a case report

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mirjana Bjeloš ◽  
Ana Križanović ◽  
Mladen Bušić ◽  
Biljana Kuzmanović Elabjer
Keyword(s):  
Case Report ◽  
Central Retinal Artery Occlusion ◽  
Retinal Artery Occlusion ◽  
Neovascular Glaucoma ◽  
Artery Occlusion ◽  
Central Retinal Artery ◽  
Venous Stasis ◽  
Vein Occlusion ◽  
Arterial Inflow ◽  
Retinal Artery

Abstract Background In this case report, we present for the first time central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO) as a complication of persistent hyaloid artery (PHA). Case presentation In August 2019, a six-year-old male patient manifested right eye (RE) excessive tearing, conjunctival injection and pain. On examination, RE demonstrated light perception and intraocular pressure of 36 mmHg. The diagnoses of neovascular glaucoma, CRVO and CRAO were established as affirmed with fluorescein angiography (FA). PHA was not reported. Extensive work-up and family history were unremarkable. The child was born on term after uncomplicated twin pregnancy. In December 2019, he was referred to our Centre. Transillumination revealed fully dilated, non-reactive RE pupil, clear lens and tubular remnant of HA containing blood cells in its lumen freely rotating in the anterior vitreous. Conclusions PHA results from failure of apoptosis during gestation. It can easily be observed during the red reflex screening at neonatal wards. We hypothesized that PHA twisting led to torsion of the residual primordial common bulb, branching off to HA and CRA with CRAO occurring first. The consequential CRVO presumably advanced by venous stasis due to decrease in arterial inflow. Liquid vitreous appears as early as 4 years of age enabling PHA to whirl more freely. Thus, in case of PHA, we advocate FA to be performed and if connection with retinal artery is proven, parents should be informed on the possible devastating complications and prompt surgical treatment should be considered.

Sign in / Sign up

Export Citation Format

Share Document