scholarly journals Physiological and biological predictors of length of stay and recovery in adults with acute asthma: An observational cohort study

2016 ◽  
Vol 12 (1) ◽  
pp. 200-206 ◽  
Author(s):  
Thomas L. Jones ◽  
Jonathon Owen ◽  
Scott Elliott ◽  
Thomas Brown ◽  
Dominic Reynish ◽  
...  
Keyword(s):  
Cohort Study ◽  
Length Of Stay ◽  
Acute Asthma ◽  
Observational Cohort Study ◽  
Observational Cohort

scholarly journals Timing and burden of persistent critical illnessin UK intensive care units: An observational cohort study

2021 ◽  
pp. 175114372110471
Author(s):  
David A Harrison ◽  
Ben C Creagh-Brown ◽  
Kathryn M Rowan
Keyword(s):  
Cohort Study ◽  
Intensive Care ◽  
Critical Illness ◽  
Length Of Stay ◽  
Observational Cohort Study ◽  
Adverse Outcomes ◽  
Admission Diagnosis ◽  
Icu Length Of Stay ◽  
Observational Cohort ◽  
Persistent Critical Illness

Background Persistent critical illness is a recognisable clinical syndrome defined conceptually as when the patient’s reason for being in the intensive care unit (ICU) is more related to their ongoing critical illness than their original reason for admission. Our objectives were: (1) to assess the day in ICU on which chronic factors (e.g., age, gender and comorbidities) were more predictive of survival than acute factors (e.g. admission diagnosis, physiological derangements) measured on the day of admission; (2) to assess the consistency of this finding across major patient subgroups and over time and (3) to compare case mix characteristics and outcomes for patients determined to develop persistent critical illness (based on ICU length of stay) with other patients. Methods Observational cohort study using a high-quality clinical database from the national clinical audit of adult critical care. 217 adult ICUs in England, Wales and Northern Ireland. 835,946 adult patients admitted to participating ICUs between 1 April 2009 and 31 March 2016. The main outcome measure was mortality at discharge from acute hospital. Results We fitted two statistical models (‘chronic’ and ‘acute’) and updated these based upon patients with an ICU length of stay of at least 1, 2, etc., up to 28 days. The discrimination of the chronic model first exceeded that of the acute model on day 11. Patients with longer stays (>10 days) comprised 9% of admissions but used 45% of ICU bed-days. After a mean ICU length of stay of 22 days and a subsequent 28 days in hospital, 30% died. Conclusions Persistent critical illness is commonly encountered in clinical practice and is associated with increased healthcare utilisation and adverse outcomes. Improvements in our understanding of the longer term outcomes and in the development of tools to aid prognostication are urgently required – for humane as well as health economic reasons.

scholarly journals Retrospective observational cohort study of mortality and length of stay for surgical ICU admissions

Critical Care ◽  
2015 ◽  
Vol 19 (Suppl 1) ◽  
pp. P519
Author(s):  
M Hameed ◽  
M Maruthappu ◽  
D Marshall ◽  
M Pimentel ◽  
L Celi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Length Of Stay ◽  
Observational Cohort Study ◽  
Observational Cohort ◽  
Surgical Icu ◽  
Retrospective Observational Cohort Study

scholarly journals Length of Stay Comparison between Rivaroxaban and Warfarin in the Treatment of Pulmonary Embolism: Results from a Real-World Observational Cohort Study

Thrombosis ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Kirsten M. Roberts ◽  
Tamara B. Knight ◽  
Eimeira Padilla-Tolentino ◽  
Manasa Murthy ◽  
Evan J. Peterson
Keyword(s):  
Pulmonary Embolism ◽  
Cohort Study ◽  
Length Of Stay ◽  
Oral Anticoagulant ◽  
Oral Anticoagulants ◽  
Observational Cohort Study ◽  
Time Interval ◽  
Secondary Endpoints ◽  
Observational Cohort ◽  
Post Hoc

Background. Trials have shown that novel oral anticoagulants may decrease length of stay versus warfarin. A comparison of length of stay in the treatment of pulmonary embolism (PE) has not been performed outside post hoc analysis of a large clinical trial. Objective. To evaluate if rivaroxaban decreases length of stay compared to warfarin plus enoxaparin in the treatment of PE. Methods. This was a multicenter, retrospective, observational cohort study. Patients were identified based on discharge diagnosis of PE and were excluded if they received anticoagulants prior to admission and had additional indications for anticoagulation or reduced creatinine clearance. The primary endpoint was length of stay. Secondary endpoints included time from initial dose of oral anticoagulant to discharge and length of stay comparison between subgroups. Results. Inclusion criterion was met by 158 patients (82 warfarin, 76 rivaroxaban). The median length of stay was 4.5 days (interquartile range [IQR], 2.7, 5.9) in the warfarin group and 1.8 days (IQR, 1.2, 3.7) in the rivaroxaban group (P<0.001). Time interval from first dose of oral anticoagulant to discharge was shorter with rivaroxaban (P<0.001). Conclusions. Patients given rivaroxaban had decreased length of stay versus those given warfarin plus enoxaparin for the treatment of PE.

Influence of vitamin D on outcomes following burn injury: An observational cohort study

2017 ◽  
Author(s):  
Khaled Al-Tarrah ◽  
Carl Jenkinson ◽  
Martin Hewison ◽  
Naiem Moiemen ◽  
Janet Lord
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Burn Injury ◽  
Observational Cohort Study ◽  
Observational Cohort

The Pros and Cons of Gastric Bypass Surgery in Obese Individuals with Type 2 Diabetes—Nationwide, Matched, Observational Cohort Study

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 131-OR
Author(s):  
VASILEIOS LIAKOPOULOS ◽  
ANN-MARIE SVENSSON ◽  
INGMAR NASLUND ◽  
BJORN ELIASSON
Keyword(s):  
Type 2 Diabetes ◽  
Gastric Bypass ◽  
Cohort Study ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Observational Cohort Study ◽  
Observational Cohort ◽  
Pros And Cons
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