scholarly journals Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives

2015 ◽  
Vol 48 (6) ◽  
pp. 705-717 ◽  
Author(s):  
G. Franci ◽  
G. Manfroni ◽  
R. Cannalire ◽  
T. Felicetti ◽  
O. Tabarrini ◽  
...  
Keyword(s):  
Cell Death ◽  
Population Growth ◽  
Growth Inhibition ◽  
Cell Population ◽  
Tumour Cell ◽  
Cell Population Growth ◽  
Tumour Cell Population

scholarly journals Modelling cell population growth with applications to cancer therapy in human tumour cell lines

2004 ◽  
Vol 85 (2-3) ◽  
pp. 353-368 ◽  
Author(s):  
Britta Basse ◽  
Bruce C. Baguley ◽  
Elaine S. Marshall ◽  
Graeme C. Wake ◽  
David J.N. Wall
Keyword(s):  
Cancer Therapy ◽  
Population Growth ◽  
Cell Lines ◽  
Cell Population ◽  
Tumour Cell ◽  
Human Tumour ◽  
Cell Population Growth ◽  
Tumour Cell Lines ◽  
Human Tumour Cell Lines

scholarly journals Cell population growth regulates dorsalization and caudalization during chick morphogenesis and programmed cell death in lens fibres

2020 ◽  
Vol 64 (1-2-3) ◽  
pp. 45-57
Author(s):  
Sohan Prabhakar Modak
Keyword(s):  
Cell Cycle ◽  
Cell Death ◽  
Chick Embryo ◽  
Programmed Cell Death ◽  
Population Growth ◽  
Cell Population ◽  
Neural Induction ◽  
Egg Yolk ◽  
Rna Sequences ◽  
Cell Population Growth

The chick embryo ectoblast was examined for a possible relationship between the state of neural competence and cell population growth. It was found that although ectoblast cells with doubling times ranging between 5 to 20 h exhibit neural competence, the extent of neutralization induced by the Hensen’s node depends on the duration of the cell cycle; the longer the doubling time of the competent ectoblast, the stronger the induction and the greater the induced neural tissue. Neural induction in the competent ectoblast occurs in at least two steps: the first lasts for 1-2 h of direct contact with the inducing Hensen’s node graft; a contact for another 2 h with even a non-inducing post-nodal fragment is essential to consolidate neutralization. Hensen’s node graft induces mitotic activity in the competent ectoblast in contact. Teratogens which inhibit cell population growth, development and blastoderm expansion in chick embryo gastrula cause concomitant caudalization of the embryonic axis. We confirm Yamada’s hypothesis that dorsalization is under positive mitogenic control, whereas caudalization is controlled by a negative cell cycle regulation. Reverse transcripts of chick gastrula mRNA were cloned in pBR322. Colony hybridization with cDNA made against chicken yolk RNA showed positive clones. Thus chicken yolk contains maternal mRNAs. cDNA made against mRNA extracted from stage 10 foreheads was hybridized with RNA from stage 1 to 13 embryos, 19 day lens and egg yolk. The hybridization signal, which was low between stages 1 to 7, increased between stages 10-13 and decreased thereafter. Forehead cDNA also hybridized to yolk RNA. Thus, maternal RNA sequences are present in the early chick embryo. During lens development, epithelial cells retain proliferative activity and their progeny reaching a stationary phase join the fibre area and contribute to the growth of fibre cells. The rate of transfer from epithelium to fibre regulates the rate of programmed cell death of the non-dividing differentiated lens fibre cells.

scholarly journals Circadian rhythm and cell population growth

2011 ◽  
Vol 53 (7-8) ◽  
pp. 1558-1567 ◽  
Author(s):  
Jean Clairambault ◽  
Stéphane Gaubert ◽  
Thomas Lepoutre
Keyword(s):  
Circadian Rhythm ◽  
Population Growth ◽  
Cell Population ◽  
Cell Population Growth

scholarly journals Finsler-type estimators for the cancer cell population dynamics

2015 ◽  
Vol 98 (112) ◽  
pp. 53-69
Author(s):  
Vladimir Balan ◽  
Jelena Stojanov
Keyword(s):  
Dynamical System ◽  
Population Growth ◽  
Cancer Cell ◽  
Cell Population ◽  
Biological Models ◽  
Cell Population Dynamics ◽  
Finsler Structure ◽  
Cell Population Growth ◽  
Cancer Cell Population ◽  
The Difference

We introduce a Finslerian model related to the classical Garner dynamical system, which models the cancer cell population growth. The Finsler structure is determined by the energy of the deformation field-the difference of the fields, which describe the reduced and the proper biological models. It is shown that a certain locally-Minkowski anisotropic Randers structure, obtained by means of statistical fitting, is able to provide a Zermelo-type drift of the overall cancer cell population growth, which occurs due to significant changes within the cancerous process. The geometric background, the applicative advantages and perspective openings of the constructed geometric structure are discussed.

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