Per‐rectal portal scintigraphy as an alternative measure of hepatic venous pressure gradient in chronic liver disease: a preliminary report

2021 ◽  
Author(s):  
Kohei Kotani ◽  
Sawako Uchida‐Kobayashi ◽  
Akira Yamamoto ◽  
Etsushi Kawamura ◽  
Masaru Enomoto ◽  
...  
Keyword(s):  
Liver Disease ◽  
Pressure Gradient ◽  
Chronic Liver Disease ◽  
Preliminary Report ◽  
Venous Pressure ◽  
Chronic Liver ◽  
Hepatic Venous Pressure Gradient ◽  
Alternative Measure

scholarly journals Chronic Liver Disease: Noninvasive Subharmonic Aided Pressure Estimation of Hepatic Venous Pressure Gradient

Radiology ◽  
2013 ◽  
Vol 268 (2) ◽  
pp. 581-588 ◽  
Author(s):  
John R. Eisenbrey ◽  
Jaydev K. Dave ◽  
Valgerdur G. Halldorsdottir ◽  
Daniel A. Merton ◽  
Cynthia Miller ◽  
...  
Keyword(s):  
Liver Disease ◽  
Pressure Gradient ◽  
Chronic Liver Disease ◽  
Venous Pressure ◽  
Chronic Liver ◽  
Hepatic Venous Pressure Gradient ◽  
Pressure Estimation

Hepatic venous pressure gradient as a predictor of fibrosis in chronic liver disease because of hepatitis B virus

2008 ◽  
Vol 28 (5) ◽  
pp. 690-698 ◽  
Author(s):  
Manoj Kumar ◽  
Ashish Kumar ◽  
Syed Hissar ◽  
Pankaj Jain ◽  
Archana Rastogi ◽  
...  
Keyword(s):  
Liver Disease ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Pressure Gradient ◽  
Chronic Liver Disease ◽  
Venous Pressure ◽  
Chronic Liver ◽  
Hepatic Venous Pressure Gradient ◽  
B Virus

Portal Angiogenesis in Chronic Liver Disease Patients Correlates with Portal Pressure and Collateral Formation

2019 ◽  
Vol 37 (6) ◽  
pp. 498-508 ◽  
Author(s):  
Carolina A. Serrano ◽  
Simon C. Ling ◽  
Sofia Verdaguer ◽  
Miguel León ◽  
Nicolás Jarufe ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Portal Hypertension ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Venous Pressure ◽  
Portal Pressure ◽  
Peripheral Circulation ◽  
Chronic Liver ◽  
Noninvasive Markers ◽  
Collateral Formation

Background/Aims: One hallmark of chronic liver disease in patients with portal hypertension is the formation of portal-systemic collaterals in which angiogenesis has a fundamental role. We studied patients with chronic liver disease undergoing liver transplantation to correlate levels of circulating angiogenic factors in portal and peripheral circulation with portal pressure and portal-systemic collaterals. Methods: Sixteen patients who underwent liver transplantation were enrolled. During transplant surgery, we determined portal venous pressure and portal-systemic collateral formation. We determined angiogenics mediator levels in systemic and portal plasma. Peripheral plasma from healthy donors was measured as controls. Results: Vascular endothelial growth factor (VEGF)-R1 and 2, Ang-1 and 2, Tie2, FGF- 1 and 2, CD163, PDGFR-β, PDGFsRα, PDGF-AB and BB, CD163, TGF-β VASH-1 levels were significantly different in the controls in comparison to cases. Significantly decreased portal venous levels of Ang-1, FGF-1, PDGF-AB/BB, and CC were observed in patients with higher portal pressure. Peripheral VEGF, Ang-1, pPDGF-AB, BB, and CC were significantly decreased in patients with more severe collateral formation. While peripheral VEGF-R1 was higher in patients with severe collateral formation. For portal circulation, VEGF, Ang-1, ­pPDGF-AB, BB, and CC were significantly decreased in patients with more severe collateral formation Conclusions: Angiogenesis factors correlated with portal pressure and collateral formation and different patterns of circulating angiogenesis mediators were found in peripheral and portal blood of patients with chronic liver disease. These results support the importance of angiogenic pathways in cirrhosis and portal hypertension and highlight areas for further study to identify clinically useful noninvasive markers of portal pressure and collateral formation.

scholarly journals Collagen proportionate area correlates to hepatic venous pressure gradient in non-abstinent cirrhotic patients with alcoholic liver disease

2018 ◽  
Vol 10 (1) ◽  
pp. 73-81 ◽  
Author(s):  
Sophie Restellini ◽  
Nicolas Goossens ◽  
Sophie Clément ◽  
Nicolas Lanthier ◽  
Francesco Negro ◽  
...  
Keyword(s):  
Liver Disease ◽  
Pressure Gradient ◽  
Alcoholic Liver Disease ◽  
Venous Pressure ◽  
Hepatic Venous Pressure Gradient ◽  
Cirrhotic Patients
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