Gamma-variate plasma clearance versus urinary plasma clearance of 51 Cr-EDTA in patients with cirrhosis with and without fluid retention

2016 ◽  
Vol 37 (6) ◽  
pp. 588-595 ◽  
Author(s):  
Stefan Fuglsang ◽  
Ulrik L. Henriksen ◽  
Hanne B. Hansen ◽  
Flemming Bendtsen ◽  
Jens H. Henriksen
Keyword(s):  
Plasma Clearance ◽  
Fluid Retention ◽  
Gamma Variate

Total plasma clearance versus urinary plasma clearance of51Cr-EDTA in patients with cirrhosis with and without fluid retention

2014 ◽  
Vol 75 (1) ◽  
pp. 64-72 ◽  
Author(s):  
Ulrik L. Henriksen ◽  
Hanne B. Hansen ◽  
Helmer Ring-Larsen ◽  
Flemming Bendtsen ◽  
Jens H. Henriksen
Keyword(s):  
Plasma Clearance ◽  
Fluid Retention ◽  
Total Plasma ◽  
Total Plasma Clearance

scholarly journals Tikhonov adaptively regularized gamma variate fitting to assess plasma clearance of inert renal markers

2010 ◽  
Vol 37 (5) ◽  
pp. 435-474 ◽  
Author(s):  
Carl A. Wesolowski ◽  
Richard C. Puetter ◽  
Lin Ling ◽  
Paul S. Babyn
Keyword(s):  
Plasma Clearance ◽  
Gamma Variate ◽  
Renal Markers

scholarly journals Validation of Tikhonov adaptively regularized gamma variate fitting with 24-h plasma clearance in cirrhotic patients with ascites

2011 ◽  
Vol 38 (12) ◽  
pp. 2247-2256 ◽  
Author(s):  
Carl Adam Wesolowski ◽  
Lin Ling ◽  
Elias Xirouchakis ◽  
Maria T. Burniston ◽  
Richard C. Puetter ◽  
...  
Keyword(s):  
Plasma Clearance ◽  
Gamma Variate ◽  
Cirrhotic Patients

Catabolism of Human Fibrinogen Fragment D in Normal Subjects and Patients with Liver Cirrhosis

1980 ◽  
Vol 44 (03) ◽  
pp. 146-149 ◽  
Author(s):  
Nicole Ardaillou ◽  
Jeannine Yvart ◽  
Philippe Le Bras ◽  
Marie-José Larrieu
Keyword(s):  
Liver Cirrhosis ◽  
Clearance Rate ◽  
Plasma Clearance ◽  
Normal Subjects ◽  
Fractional Catabolic Rate ◽  
Human Fibrinogen ◽  
Plasma Pool ◽  
Catabolic Rate ◽  
Chloramine T

SummaryThe catabolism of human fragment D, (FgD), obtained by plasmin digestion of fibrinogen has been investigated in normal subjects and patients with liver cirrhosis and the results compared with those obtained for fibrinogen (Fg). Fg was labelled with I-125 and Fg D with I-131 using the chloramine T method. The plasma disappearance curves of both labelled proteins fitted a two exponential curve. In controls the plasma clearance rate of Fg D was greater than that of Fg as shown by the marked difference between the half-lives of these two tracers: 8,9 and 83,5 hours for Fg D and Fg respectively. The fractional catabolic rate of Fg D was 3.38 times the plasma pool per day. In nine patients with liver cirrhosis, catabolism of Fg was not modified. In contrast, catabolism of Fg D was significantly reduced with a half life of 13.0 hours and a low fractional catabolic rate. These results suggest the role of the liver in the catabolism of Fg D in man.

Studies on Metabolism of Urokinase and Mechanism of Thrombolysis by Urokinase

1979 ◽  
Vol 42 (03) ◽  
pp. 885-894 ◽  
Author(s):  
Tatsuo Ueno ◽  
Norio Kobayashi ◽  
Tadashi Maekawa
Keyword(s):  
Molecular Weight ◽  
Plasma Clearance ◽  
Radioactive Material ◽  
Optimal Dosage ◽  
Plasma Clot ◽  
Optimal Dosage Regimen ◽  
Arterial Thrombus ◽  
Contact Experiment

SummaryPharmacokinetics of intravenously injected 125I-labeled urokinase (125I-UK) of a molecular weight of 33,000 daltons in normal rabbits and patients with various diseases were investigated. The plasma clearance of 125I-UK in rabbits was described by a biexponential curve within six hours with a half-life of 8 minutes, 2.3 hours, respectively. The radioactivity in the liver and kidneys 15 minutes after iv injection with 125I-UK was 9.6% and 14.0% of the radioactivity injected, respectively. Approximately 80% of the total radioactive material injected was excreted in the urine in 18 hours. No increase in activator activity in the urine was observed after a large amount of UK injection. Activity uptake of 125I-UK by experimentally induced arterial thrombus was little. Lysis of the stasis thrombus was produced by injecting 7.5 × 104 IU of UK in only one out of 8 rabbits. In vitro contact experiment revealed that transfer of 125I-UK to plasma clot is slow (24 hours for 10% of 125I-UK by plasma clot). In 4 patients plasma clearance of 125I-UK was essentially similar to that in rabbits. From the results obtained optimal dosage regimen of UK administration for complete thrombolysis in vivo was discussed.

Fluid retention in patients with paroxysmal and permanent atrial fibrillation and heart failure

2020 ◽  
Vol 19 (5) ◽  
pp. 2402
Author(s):  
V. V. Kirillova ◽  
L. A. Sokolova ◽  
A. A. Garganeyeva ◽  
V. N. Meshchaninov ◽  
R. E. Batalov
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Fluid Retention ◽  
Permanent Atrial Fibrillation

Fracturing fluid retention in shale gas reservoirs:mechanisms and functions

2019 ◽  
Vol 12 (24) ◽  
Author(s):  
Lijun You ◽  
Yang Zhou ◽  
Yili Kang ◽  
Bin Yang ◽  
Zhongyu Cui ◽  
...  
Keyword(s):  
Shale Gas ◽  
Fluid Retention ◽  
Fracturing Fluid
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