Three-phase bone scintigraphy for diagnosis of Charcot neuropathic osteoarthropathy in the diabetic foot - does quantitative data improve diagnostic value?

2015 ◽  
Vol 37 (1) ◽  
pp. 30-36 ◽  
Author(s):  
M. Fosbøl ◽  
S. Reving ◽  
E. H. Petersen ◽  
P. Rossing ◽  
M. Lajer ◽  
...  
Keyword(s):  
Bone Scintigraphy ◽  
Diabetic Foot ◽  
Quantitative Data ◽  
Diagnostic Value ◽  
Three Phase ◽  
Charcot Neuropathic Osteoarthropathy ◽  
Neuropathic Osteoarthropathy

Diagnostic Value of Tl-201 and Three-Phase Bone Scintigraphy for Bone and Soft-Tissue Tumors

2000 ◽  
Vol 25 (3) ◽  
pp. 200-205 ◽  
Author(s):  
YOSHIHIRO NISHIYAMA ◽  
YUKA YAMAMOTO ◽  
YOSHIHIRO TOYAMA ◽  
KATASHI SATOH ◽  
MOTOOMI OHKAWA ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Bone Scintigraphy ◽  
Diagnostic Value ◽  
Soft Tissue Tumors ◽  
Three Phase

Follow-up of Osteomyelitis of Infants with Systemic Serum Parameters and Bone Scintigraphy

1996 ◽  
Vol 35 (04) ◽  
pp. 116-121 ◽  
Author(s):  
G. E Fueger ◽  
M. Vejda ◽  
R. M. Aigner
Keyword(s):  
Bone Scintigraphy ◽  
Antibiotic Treatment ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Laboratory Findings ◽  
Radiographic Findings ◽  
Serum Parameters ◽  
Wbc Count ◽  
Differential White Blood Cell

Summary Aim: To prevent orthopedic sequelae in acute hematogenous pyogenic osteomyelitis (AHPO) of infants early diagnosis, recognition of recurrence and effective therapy is needed. This retrospective study of 47 infants with bacteriologically confirmed AHPO concerned with an analysis of the diagnostic value of systemic serum parameters compared to bone scintigraphy (BSC). Methods: AHPO was characterized initially and during the course of disease by clinical findings, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), total and differential white blood cell (WBC) count, BSC, and plain radiography. Results: CRP was the most effective serum parameter for follow- up of disease. The first sign of BSC to signal adequate response to antibiotic treatment was the decrease or normalization of hyperperfusion. Escape from therapy or poor prognosis, even when the serum parameters were normalized, was signaled by the recurrence of focal hyperperfusion and the persistent or increasing local uptake ratios on the 3-h-image over 6 weeks during a course of antibiotic treatment. Conclusion: Antibiotic treatment masks the clinical presentation, and the radiographic findings, causes non-characteristic laboratory findings, but do not prevent the scintigraphic visualization; BSC and serum parameters used in the right completion are the most successful and efficient modalities for follow-up of AHPO. Maintenance of antibiotic therapy should be done until BSC findings have reverted to normal.

Diagnostic value of procalcitonin, erythrocyte sedimentation rate (ESR), quantitative C-reactive protein (CRP) and clinical findings associated with osteomyelitis in patients with diabetic foot

2021 ◽  
pp. 1-7
Author(s):  
Zahra Soleimani ◽  
Fatemeh Amighi ◽  
Zarichehr Vakili ◽  
Mansooreh Momen-Heravi ◽  
Seyyed Alireza Moravveji
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Roc Curve ◽  
Diabetic Foot ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Diabetic Patients ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

BACKGROUND: The diagnosis of osteomyelitis is a key step of diabetic foot management. Procalcitonin (PCT) is a novel infection marker. This study aimed to investigate the diagnostic value of procalcitonin and other conventional infection markers and clinical findings in diagnosis of osteomyelitis in diabetic foot patients. METHODS AND MATERIALS: This diagnostic value study was carried out on ninety patients with diabetic infected foot ulcers admitted in Kashan Beheshti Hospital, 2016. After obtaining consent, 10 cc blood sample was taken for measuring serum PCT, CBC, ESR, CRP and FBS. Clinical characteristics of the wounds were noted. Magnetic resonance imaging of the foot was performed in all patients to diagnose osteomyelitis. All statistical analyses were done with the use of SPSS-16. RESULTS: PCT levels were 0.13 ± 0.02 ng/mili patients with osteomyelitis (n= 45) and 0.04 ± 0.02 ng/ml in patients without osteomyelitis (n= 45). PCT, Erythrocyte sedimentation rate and C-reactive protein was found significantly higher in patients with osteomyelitis (p< 0.001). The ROC curve was calculated for PCT. The area under the ROC curve for infection identification was 1 (p< 0.001). The best cut-off value for PCT was 0.085 ng/ml. Sensitivity, specificity, and positive and negative predictive values were 100%, 97.8%,97.8% and 100%, respectively. CONCLUSION: In this group of patients, PCT was useful to discriminate patients with bone infection. Also, Erythrocyte sedimentation rate and C-reactive protein can be used as a marker of osteomyelitis in diabetic patients.

scholarly journals MRI and bone scintigraphy for breast cancer bone metastase: a meta-analysis

Open Medicine ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. 317-323 ◽  
Author(s):  
Yue Rong ◽  
Hong Ren ◽  
Xianjun Ding
Keyword(s):  
Breast Cancer ◽  
Magnetic Resonance ◽  
Comparative Study ◽  
Bone Metastases ◽  
Bone Scintigraphy ◽  
Magnetic Resonance Image ◽  
Meta Analysis ◽  
Diagnostic Value ◽  
Satisfactory Method ◽  
The Comparative Study

AbstractObjectiveThe aim of this study was to compare the diagnostic value of magnetic resonance image (MRI) and bone scintigraphy (BS) in the diagnosis of breast cancer bone metastases.MethodsSearching in the databases including PubMed, Embase about the comparative study of MRI and bone scintigraphy in the diagnosis of breast cancer bone metastases during 2000~2018. After we screened further, the extracted effective data were calculated by Meta-Disc 1.4 software.ResultsWe obtained 4 articles. The pooled estimates for sensitivity of MRI, BS were 0.99 (95% CI, [0.95, 1.00]) and 0.93 (95% CI, [0.88, 0.97]) respectively; For specificity were 0.99 (95% CI, [0.95, 1.00]) and 0.86 (95% CI, [0.79, 0.92]) respectively. The AUC of SROC curve for MRI and BS were 0.9948 and 0.9675 respectively.ConclusionMRI remains to be a satisfactory method for the diagnosis of breast cancer bone metastases and should first be considered for patients.

scholarly journals Usefulness of asymmetry score on quantitative three-phase bone scintigraphy in the evaluation of complex regional pain syndrome

2013 ◽  
Vol 28 (1) ◽  
pp. 11 ◽  
Author(s):  
BhagwantRai Mittal ◽  
Ashwani Sood ◽  
Anish Bhattacharya ◽  
Aman Sharma ◽  
Sasikumar Arun ◽  
...  
Keyword(s):  
Complex Regional Pain Syndrome ◽  
Bone Scintigraphy ◽  
Pain Syndrome ◽  
Three Phase

Diagnostic Value of Tc-99m (V) DMSA for Chondrogenic Tumors With Positive Tc-99m HMDP Uptake on Bone Scintigraphy

1995 ◽  
Vol 20 (4) ◽  
pp. 361-364 ◽  
Author(s):  
HISATAKA KOBAYASHI ◽  
YOSHIHIKO KOTOURA ◽  
MARIKO HOSONO ◽  
HARUMI SAKAHARA ◽  
MAKOTO HOSONO ◽  
...  
Keyword(s):  
Bone Scintigraphy ◽  
Diagnostic Value
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