Clinical significance of circulating tumour cells and tumour marker detection in the chemotherapeutic evaluation of advanced colorectal cancer

2021 ◽  
Author(s):  
Feifei Shen ◽  
Yiwen Zhu ◽  
Fan Wang ◽  
Xun Cai ◽  
Honghua Ding ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Clinical Significance ◽  
Advanced Colorectal Cancer ◽  
Tumour Marker ◽  
Tumour Cells ◽  
Circulating Tumour Cells ◽  
Marker Detection

scholarly journals Clinical significance of CDX2-positive circulating tumour cells in colorectal cancer patients

2011 ◽  
Vol 104 (6) ◽  
pp. 1000-1006 ◽  
Author(s):  
S C C Wong ◽  
S S M Ng ◽  
M T Cheung ◽  
L Y Luk ◽  
C M L Chan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Clinical Significance ◽  
Tumour Cells ◽  
Circulating Tumour Cells ◽  
Colorectal Cancer Patients

scholarly journals Circulating tumour cells as a predictive factor for response to systemic chemotherapy in patients with advanced colorectal cancer

2008 ◽  
Vol 2 (4) ◽  
pp. 349-355 ◽  
Author(s):  
Silke Lankiewicz ◽  
Silke Zimmermann ◽  
Christiane Hollmann ◽  
Tina Hillemann ◽  
Tim F. Greten
Keyword(s):  
Colorectal Cancer ◽  
Predictive Factor ◽  
Systemic Chemotherapy ◽  
Advanced Colorectal Cancer ◽  
Tumour Cells ◽  
Circulating Tumour Cells

scholarly journals Therapeutic Targeting of the Tumour Microenvironment in Metastatic Colorectal Cancer

2021 ◽  
Vol 22 (4) ◽  
pp. 2067
Author(s):  
Rhynelle S. Dmello ◽  
Sarah Q. To ◽  
Ashwini L. Chand
Keyword(s):  
Colorectal Cancer ◽  
Targeted Therapy ◽  
Liver Metastasis ◽  
Metastatic Colorectal Cancer ◽  
Tumour Microenvironment ◽  
Tumour Cells ◽  
Cellular Interactions ◽  
Circulating Tumour Cells ◽  
Therapeutic Targeting ◽  
Colorectal Cancer Patients

Liver metastasis is the primary contributor to the death of patients with colorectal cancer. Despite the overall success of current treatments including targeted therapy, chemotherapy, and immunotherapy combinations in colorectal cancer patients, the prognosis of patients with liver metastasis remains poor. Recent studies have highlighted the importance of the tumour microenvironment and the crosstalk within that determines the fate of circulating tumour cells in distant organs. Understanding the interactions between liver resident cells and tumour cells colonising the liver opens new therapeutic windows for the successful treatment of metastatic colorectal cancer. Here we discuss critical cellular interactions within the tumour microenvironment in primary tumours and in liver metastases that highlight potential therapeutic targets. We also discuss recent therapeutic advances for the treatment of metastatic colorectal cancer.

scholarly journals The Clinical Significance of MiR-148a as a Predictive Biomarker in Patients with Advanced Colorectal Cancer

PLoS ONE ◽  
2012 ◽  
Vol 7 (10) ◽  
pp. e46684 ◽  
Author(s):  
Masanobu Takahashi ◽  
Miriam Cuatrecasas ◽  
Francesc Balaguer ◽  
Keun Hur ◽  
Yuji Toiyama ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Clinical Significance ◽  
Advanced Colorectal Cancer ◽  
Predictive Biomarker
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