Delayed coloanal anastomosis: an alternative option for restorative rectal cancer surgery after high‐dose pelvic radiotherapy for prostate cancer

2020 ◽  
Vol 22 (11) ◽  
pp. 1545-1552
Author(s):  
M.‐O. François ◽  
E. Buscail ◽  
V. Vendrely ◽  
B. Célérier ◽  
V. Assénat ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Rectal Cancer ◽  
Coloanal Anastomosis ◽  
Cancer Surgery ◽  
Rectal Cancer Surgery ◽  
High Dose ◽  
Pelvic Radiotherapy ◽  
Alternative Option

scholarly journals Drug-Induced Interstitial Pneumonia due to Application of FOLFOX as Adjuvant Chemotherapy after Rectal Cancer Surgery: A Case Report and Literature Review

2020 ◽  
Vol 13 (2) ◽  
pp. 768-773 ◽  
Author(s):  
Senichiro Yanagawa ◽  
Nozomi Karakuchi ◽  
Tetsuya Mochizuki ◽  
Shinya Kodama ◽  
Yukio Takeshima ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Adjuvant Chemotherapy ◽  
Interstitial Pneumonia ◽  
Steroid Therapy ◽  
Disease Free Survival ◽  
Cancer Surgery ◽  
Rectal Cancer Surgery ◽  
High Dose ◽  
Drug Induced ◽  
Steroid Pulse

The regimen of oxaliplatin with 5-fluorouracil plus l-leucovorin (FOLFOX) has become one of the most commonly used first-line chemotherapy for patients with advanced colorectal cancer and it provides an increase in disease-free survival as well as an overall survival benefit. Although FOLFOX chemotherapy has helped to improve the clinical outcomes in these patients, the regimen is associated with some therapeutic issues or uncontrolled side effects. Gastrointestinal, neurosensory, and hematological toxicities have frequently been observed in patients treated with FOLFOX, and consequently, some palliative treatment has been established to combat such complications. However, pulmonary toxicities including drug-induced interstitial pneumonia (DI-IP) is rarely observed in these patients and a curative treatment is yet to be established. DI-IP due to chemotherapy is most commonly observed in patients treated with mitomycin, paclitaxel, docetaxel, or gemcitabine. Steroid therapy is mostly used to treat DI-IP, although the efficacy of such treatments is not supported with adequate evidence. FOLFOX-induced interstitial pneumonia (FIIP) is rarely observed, and several case reports of FIIP treated with steroids have been published previously that showed the mortality is extremely high. Here, we present a 74-year-old woman who received modified FOLFOX6 as adjuvant chemotherapy after rectal cancer surgery. The patient experienced FIIP, which improved after application of steroid pulse (high-dose methylprednisolone at 1,000 mg/day for 3 days) and tapering (starting with prednisolone at 40 mg/day) therapy. Our data suggest that such a steroid therapy could represent an effective treatment option for FIIP.

scholarly journals Transanal drainage tube: alternative option to defunctioning stoma in rectal cancer surgery?

2020 ◽  
Vol 5 ◽  
pp. 6-6 ◽  
Author(s):  
Fabio Carboni ◽  
Mario Valle ◽  
Giovanni Battista Levi Sandri ◽  
Manuel Giofrè ◽  
Orietta Federici ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Cancer Surgery ◽  
Drainage Tube ◽  
Rectal Cancer Surgery ◽  
Defunctioning Stoma ◽  
Alternative Option ◽  
Transanal Drainage Tube

Impact of Specialisation in the Practice of Rectal Cancer Surgery at a District General Hospital

Endoscopy ◽  
2004 ◽  
Vol 36 (10) ◽  
Author(s):  
AL Gidwani ◽  
RS Date ◽  
D Hughes ◽  
P Neilly ◽  
R Gilliland
Keyword(s):  
Rectal Cancer ◽  
General Hospital ◽  
District General Hospital ◽  
Cancer Surgery ◽  
Rectal Cancer Surgery

Can MRI pelvimetry predict the technical difficulty of laparoscopic rectal cancer surgery?

2021 ◽  
Author(s):  
Jonathan S. Y. Hong ◽  
Marie Shella De Robles ◽  
Chris Brown ◽  
Kilian G. M. Brown ◽  
Christopher J. Young ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Technical Difficulty ◽  
Cancer Surgery ◽  
Rectal Cancer Surgery
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