Prospective pilot study of anorectal fistula closure with the OTSC Proctology

2014 ◽  
Vol 17 (1) ◽  
pp. 81-86 ◽  
Author(s):  
R. L. Prosst ◽  
A. K. Joos ◽  
W. Ehni ◽  
D. Bussen ◽  
A. Herold
Keyword(s):  
Pilot Study ◽  
Anorectal Fistula ◽  
Fistula Closure ◽  
Prospective Pilot Study

scholarly journals Endoscopic closure of refractory esophageal fistula after esophagectomy using polyglycolic acid sheets: a pilot study

2020 ◽  
Vol 08 (05) ◽  
pp. E591-E595 ◽  
Author(s):  
Yasuaki Nagami ◽  
Masaki Ominami ◽  
Taishi Sakai ◽  
Shusei Fukunaga ◽  
Fumio Tanaka ◽  
...  
Keyword(s):  
Pilot Study ◽  
Adverse Events ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Poor Quality ◽  
Esophageal Fistula ◽  
Fistula Closure ◽  
Prospective Pilot Study ◽  
Endoscopic Closure

Abstract Background and study aims Esophageal fistulas after esophagectomy are associated with high mortality and poor quality of life. They are sometimes intractable to conservative management and surgery that increases mortality. Few studies have assessed use of polyglycolic acid (PGA) sheets with fibrin glue for esophageal fistulas. We investigated the safety of using PGA sheets with fibrin glue for esophageal fistulas after esophagectomy. Patients and methods This was a single-center prospective pilot study. Patients who had refractory esophageal fistulas after esophagectomy were included. PGA sheets were filled in the fistula using biopsy forceps. Fibrin glue was applied to the PGA sheets. We repeated the procedure 1 week later. The outcome measures were the incidence of adverse events (AEs) and closure of the fistula. Results Five patients were assessed. No adverse events were observed. The esophageal fistula was closed with the application of PGA sheets four times in 40 % (2/5) of the cases. Conclusions PGA sheets with fibrin glue were safe for esophageal fistula closure after esophagectomy and do not involve the risk of AEs.

Weight gain with hyperthyroidism therapy: a prospective pilot study

2018 ◽  
Author(s):  
Angelos Kyriacou ◽  
Alexis Kyriacou ◽  
Akheel A Syed ◽  
Petros Perros
Keyword(s):  
Weight Gain ◽  
Pilot Study ◽  
Prospective Pilot Study

scholarly journals Could Daily Monitoring of Fibrin Related Markers Help Suspect a Thrombotic Event in COVID-19 Patients? A Prospective Pilot Study

TH Open ◽  
2021 ◽  
Vol 05 (02) ◽  
pp. e152-e154
Author(s):  
Thomas Lecompte ◽  
Michael Hardy ◽  
Isabelle Michaux ◽  
Alain Dive ◽  
François Mullier
Keyword(s):  
Pilot Study ◽  
Thrombotic Event ◽  
Daily Monitoring ◽  
Prospective Pilot Study

scholarly journals THU0642-HPR EVOLUTION OF THE PERCEPTIONS OF RA PATIENTS AFTER EDUCATION PATIENT SESSION TEACHING METHOTREXATE SELF-INJECTION A PROSPECTIVE PILOT STUDY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 566.1-566
Author(s):  
S. Afilal ◽  
H. Rkain ◽  
B. Berchane ◽  
J. Moulay Berkchi ◽  
S. Fellous ◽  
...  
Keyword(s):  
Pilot Study ◽  
Patient Education ◽  
Median Duration ◽  
Large Scale ◽  
Education Session ◽  
Prospective Pilot Study ◽  
Mean Delay ◽  
Lack Of Information ◽  
Level Of Satisfaction ◽  
Before And After

Background:Methotrexate is a gold standard for treatment of RA. In our context, RA patients prefer to be injected by paramedics rather than self-injecting. This can be explained by patients’ bad perceptions of self-injection or lack of information. Appropriate self-injection education can therefore be an important element in overcoming these obstacles and improving disease self-management.Objectives:Compare the RA patients’ perceptions on methotrexate self-injection before and after a patient education session.Methods:Prospective pilot study that included 27 consecutive patients (81.5% female, mean age 44.4 years, illiteracy rate 40.7%) with RA (median duration of progression of 4 years, mean delay in referral for specialist of 6 months, median duration of methotrexate use of 1 year). The patients benefited from an individual patient education session to learn how to self-inject with methotrexate subcutaneously. The patient education session was supervised by a nurse and a rheumatologist with a control a week later. Perceptions of the reluctance to self-inject and the difficulties encountered by patients were assessed before the patient education session, after the 1st and 2nd self-injection of methotrexate using a 10 mm visual analog scale. Patients also reported their level of satisfaction (10 mm VAS) after the 1st and 2nd self-injection.Results:The mean duration of patient education session is 13 min.Table I compares the evolution of the degrees of reluctance to self-injection, the difficulties encountered, and the satisfaction experienced by the patients.Table 1.Evolution of RA patients’ perceptions on the methotrexate self-injection. (N = 27)BeforeAfter the 1stself-injectionAfter the 2end self-injectionpVAS reluctance (0-10mm)6,5 ± 3,62,2 ± 2,91,0 ± 2,3<0,0001VAS difficulty (0-10mm)7,5 ± 2,62,5 ± 2,71,0 ± 1,9<0,0001VAS satisfaction (0-10mm)-8,9 ± 1,89,5 ± 1,50,002Conclusion:This study suggests the effectiveness of a methotrexate self-injection patient education session in RA patients. It also highlights the value of patient education in rheumatologic care. A large-scale study is necessary to better interpret and complete these preliminary results from this pilot study.Disclosure of Interests:None declared

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