Clinical relevance of positron emission tomography/computed tomography-positive inguinal nodes in rectal cancer after neoadjuvant chemoradiation

2013 ◽  
Vol 15 (6) ◽  
pp. 674-682 ◽  
Author(s):  
R. O. Perez ◽  
A. Habr-Gama ◽  
G. P. São Julião ◽  
I. Proscurshim ◽  
C. R. Ono ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Rectal Cancer ◽  
Clinical Relevance ◽  
Neoadjuvant Chemoradiation ◽  
Emission Tomography ◽  
Positron Emission

scholarly journals Accuracy of positron emission tomography/computed tomography and clinical assessment in the detection of complete rectal tumor regression after neoadjuvant chemoradiation

Cancer ◽  
2011 ◽  
Vol 118 (14) ◽  
pp. 3501-3511 ◽  
Author(s):  
Rodrigo Oliva Perez ◽  
Angelita Habr-Gama ◽  
Joaquim Gama-Rodrigues ◽  
Igor Proscurshim ◽  
Guilherme Pagin São Julião ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Clinical Assessment ◽  
Tumor Regression ◽  
Neoadjuvant Chemoradiation ◽  
Rectal Tumor ◽  
Emission Tomography ◽  
Positron Emission

scholarly journals Efficacy of Positron Emission Tomography in Diagnosis of Lateral Lymph Node Metastases in Patients with Rectal Cancer: A retrospective study

2020 ◽  
Author(s):  
Ryohei Yukimoto ◽  
Mamoru Uemura ◽  
Takahiro Tsuboyama ◽  
Tsuyoshi Hata ◽  
Shiki Fujino ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Rectal Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Emission Tomography ◽  
Short Axis ◽  
Cutoff Value ◽  
Positron Emission ◽  
Pet Ct

Abstract Background The presence of lateral pelvic lymph node (LLN) metastasis is an essential prognostic factor in rectal cancer patients. Thus, preoperative diagnosis of LLN metastasis is clinically important to determine the therapeutic strategy. The aim of this study was to evaluate the efficacy of preoperative positron emission tomography/computed tomography (PET/CT) in the diagnosis of LLN metastasis. Methods Eighty-six patients with rectal cancer who underwent LLN dissection at Osaka University were included in this study. The maximum standardized uptake value (SUVmax) of the primary tumor and LLN were preoperatively calculated using PET/CT. Simultaneously, the short axis of the lymph node was measured using multi-detector row computed tomography (MDCT). The presence of metastases was evaluated by postoperative pathological examination. Results Of the 86 patients, LLN metastases developed in the left, right, and both LLN regions in 7, 8, and 2 patients, respectively. The diagnosis of the metastases was predicted with a sensitivity of 84%, specificity 94%, positive predictive value 62%, and negative predictive value 98% when the cutoff value of the LLN SUVmax was set at 1.5. The cutoff value of the short axis set at 7 mm on MDCT was most useful in diagnosing LLN metastases, but SUVmax was even more useful in terms of specificity.Conclusions The cutoff value of 1.5 for lymph node SUVmax in PET is a reasonable measure to predict the risk of preoperative LLN metastases in rectal cancer patients.

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