Drug‐induced aseptic meningitis to ibuprofen: The first case confirmed by positive patch test

2020 ◽  
Vol 82 (6) ◽  
pp. 405-406 ◽  
Author(s):  
Leonardo Bianchi ◽  
Rossella Marietti ◽  
Katharina Hansel ◽  
Marta Tramontana ◽  
Cataldo Patruno ◽  
...  
Keyword(s):  
Patch Test ◽  
Aseptic Meningitis ◽  
Drug Induced ◽  
Positive Patch Test ◽  
First Case

First case of skin allergy to pregabalin with positive patch test reaction

2019 ◽  
Vol 81 (1) ◽  
pp. 78-78 ◽  
Author(s):  
Elisa Gómez Torrijos ◽  
Lucía Moreno Lozano ◽  
Alba Mª Extrmera Ortega ◽  
Oscar Gonzalez Jimenez ◽  
Alejandro R. Gratacós Gómez ◽  
...  
Keyword(s):  
Patch Test ◽  
Test Reaction ◽  
Positive Patch Test ◽  
First Case ◽  
Skin Allergy

scholarly journals First case of DRESS syndrome caused by hydroxychloroquine with a positive patch test

2020 ◽  
Vol 84 (1) ◽  
pp. 50-51 ◽  
Author(s):  
Araceli Castro Jiménez ◽  
Nuria Navarrete Navarrete ◽  
Alejandro R. Gratacós Gómez ◽  
Fernando Florido López ◽  
Rosa García Rodríguez ◽  
...  
Keyword(s):  
Patch Test ◽  
Dress Syndrome ◽  
Positive Patch Test ◽  
First Case

scholarly journals Drug-induced Bullous Pemphigoid with Positive Patch Test and in vitro IgE Sensitization

2005 ◽  
Vol -1 (1) ◽  
pp. 1-1
Author(s):  
Jakob Borch ◽  
Klaus Andersen ◽  
Ole Clemmensen ◽  
Carsten Bindslev-Jensen
Keyword(s):  
Patch Test ◽  
Bullous Pemphigoid ◽  
Drug Induced ◽  
Positive Patch Test

scholarly journals Drug-induced Eosinophilia and Multisystemic Failure with Positive Patch-Test Reaction to Spironolactone: DRESS Syndrome

2003 ◽  
Vol 84 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Pierre-Dominique Ghislain ◽  
Anne-Dominique Bodarwe ◽  
Olivier Vanderdonckt ◽  
Dominique Tennstedt ◽  
Liliane Marot ◽  
...  
Keyword(s):  
Patch Test ◽  
Dress Syndrome ◽  
Test Reaction ◽  
Drug Induced ◽  
Positive Patch Test

scholarly journals Ibuprofen-Induced Aseptic Meningitis in a Male Adolescent with Intracranial Hypertension and Visual Impairment: A Case Report

2021 ◽  
Vol 13 (1) ◽  
pp. 233-238
Author(s):  
Seyed Mohammad Mousavi Mirzaei ◽  
Zahra Ahmadi
Keyword(s):  
Visual Impairment ◽  
Intracranial Hypertension ◽  
Aseptic Meningitis ◽  
Rare Complication ◽  
Clinical Signs ◽  
Male Adolescent ◽  
Drug Induced ◽  
Blurred Vision ◽  
Inflammatory Drugs

Drug-induced aseptic meningitis (DIAM) is a rare complication of certain drugs, most commonly reported with ibuprofen use. The present study reports on a male adolescent with intracranial hypertension and visual impairment accompanied by DIAM. We present a 16-year-old male patient who after ibuprofen consumption displayed headache, fever, photophobia, and blurred vision following heavy exercises. Examination of cerebrospinal fluid showed a mononuclear pleocytosis and an increase in protein concentration. Other examinations had normal results. The development of common clinical signs following ibuprofen use reflected DIAM. The patient’s vision was found to improve with supportive care and stopping of the drug during follow-up. Given the widespread use of nonsteroidal anti-inflammatory drugs and the fact that these drugs are the most common cause of DIAM, the probability of occurrence of this event should be always kept in mind, and screening for autoimmune diseases in these patients is of great importance.

scholarly journals Bittersweet: infective complications of drug-induced glycosuria in patients with diabetes mellitus on SGLT2-inhibitors: two case reports

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Caroline Bartolo ◽  
Victoria Hall ◽  
N. Deborah Friedman ◽  
Chloe Lanyon ◽  
Andrew Fuller ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Fungal Infections ◽  
Case Reports ◽  
Sglt2 Inhibitor ◽  
Sglt2 Inhibitors ◽  
Urogenital Tract ◽  
Hypoglycemic Agents ◽  
Drug Induced ◽  
First Case ◽  
Increased Risk

Abstract Background Sodium-glucose co-transporter 2 (SGLT2) inhibitors are novel hypoglycemic agents which reduce reabsorption of glucose at the renal proximal tubule, resulting in significant glycosuria and increased risk of genital mycotic infections (GMI). These infections are typically not severe as reported in large systematic reviews and meta-analyses of the medications. These reviews have also demonstrated significant cardiovascular benefits through other mechanisms of action, making them attractive options for the management of Type 2 diabetes mellitus (T2DM). We present two cases with underlying abnormalities of the urogenital tract in which the GMI were complicated and necessitated cessation of the SGLT2 inhibitor. Case presentations Both cases are patients with T2DM on empagliflozin, an SGLT2 inhibitor. The first case is a 64 year old man with Candida albicans balanitis and candidemia who was found to have an obstructing renal calculus and prostatic abscess requiring operative management. The second case describes a 72 year old man with Candida glabrata candidemia who was found to have prostatomegaly, balanitis xerotica obliterans with significant urethral stricture and bladder diverticulae. His treatment was more complex due to fluconazole resistance and concerns about urinary tract penetration of other antifungals. Both patients recovered following prolonged courses of antifungal therapy and in both cases the SGLT2 inhibitor was ceased. Conclusions Despite their cardiovascular benefits, SGLT2 inhibitors can be associated with complicated fungal infections including candidemia and patients with anatomical abnormalities of the urogenital tract may be more susceptible to these infections as demonstrated in these cases. Clinicians should be aware of their mechanism of action and associated risk of infection and prior to prescription, assessment of urogenital anatomical abnormalities should be performed to identify patients who may be at risk of complicated infection.

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