Allergic contact dermatitis caused by isobornyl acrylate in the Enlite glucose sensor and the Paradigm MiniMed Quick‐set insulin infusion set

2019 ◽  
Vol 81 (6) ◽  
pp. 432-437 ◽  
Author(s):  
Anne Herman ◽  
Marie Baeck ◽  
Laurence Montjoye ◽  
Magnus Bruze ◽  
Emil Giertz ◽  
...  
Dermatitis ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Martin Mowitz ◽  
Tina Lejding ◽  
Josefin Ulriksdotter ◽  
Annarita Antelmi ◽  
Magnus Bruze ◽  
...  

2018 ◽  
Vol 12 (3) ◽  
pp. 630-633 ◽  
Author(s):  
Stefanie Kamann ◽  
Olivier Aerts ◽  
Lutz Heinemann

In the past decade, new diabetes technologies, including continuous glucose monitoring (CGM) systems, support patients with diabetes in their daily struggle with achieving a good glucose control. However, shortly after the first CGM systems appeared on the market, also the first concerns about adverse skin reactions were raised. Most patients claimed to suffer from (sometimes severe) skin irritation, or even allergy, which they related to the (acrylate-based) adhesive part of the device. For a long time the actual substance that caused these skin reactions with, for example, the Flash Glucose Monitoring system (iscCGM; Freestyle® Libre) could not be identified; however, recently Belgian and Swedish dermatologists reported that the majority of their patients that have developed a contact-allergic while using iscCGM react sensitively to a specific acrylate, that is, isobornyl acrylate (IBOA). Subsequently they showed by means of gas chromatography-mass spectrometry that this substance is present in the case of the glucose sensor attached by an adhesive to the skin. We report three additional cases from Germany, including a 10-year-old boy, suffering from severe allergic contact dermatitis to IBOA.


2017 ◽  
Vol 77 (6) ◽  
pp. 426-429 ◽  
Author(s):  
Caroline Peeters ◽  
Anne Herman ◽  
An Goossens ◽  
Magnus Bruze ◽  
Martin Mowitz ◽  
...  

2020 ◽  
Vol 78 (4) ◽  
pp. 381-384
Author(s):  
C. S. Queirós ◽  
M. I. Alexandre ◽  
P. M. Garrido ◽  
L. Soares de Almeida ◽  
T. Correia ◽  
...  

In the past few years, the glucose sensor FreeStyle Libre® has been associated with several cases of allergic contact dermatitis. The allergen responsible for most of these cases is isobornyl acrylate, a substance present within the sensor that migrates through the adhesive, thereby reaching the skin. Acquired leukoderma, which may occur in an area previously affected by allergic contact dermatitis, has been described in several medical devices with adhesives. However, until the present, only one case of leukoderma induced by allergic contact dermatitis to FreeStyle Libre® has been described. We report the case of a 41-year-old woman with diabetes mellitus type 1, who developed leukoderma in association with allergic contact dermatitis to this glucose sensor.


2017 ◽  
Vol 77 (6) ◽  
pp. 367-373 ◽  
Author(s):  
Anne Herman ◽  
Olivier Aerts ◽  
Marie Baeck ◽  
Magnus Bruze ◽  
Christophe De Block ◽  
...  

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