Clinical features, culprit drugs, and allergology workup in 41 cases of fixed drug eruption

2019 ◽  
Vol 81 (5) ◽  
pp. 336-340 ◽  
Author(s):  
Najah Ben Fadhel ◽  
Amel Chaabane ◽  
Helmi Ammar ◽  
Haifa Ben Romdhane ◽  
Yosra Soua ◽  
...  
2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Hossein Kavoussi ◽  
Mansour Rezaei ◽  
Katayoun Derakhshandeh ◽  
Alireza Moradi ◽  
Ali Ebrahimi ◽  
...  

Background.Generalized fixed drug eruption is a specific variant of fixed drug eruption with multifocal lesions. Diagnosis of this drug reaction is straightforward, but occasionally recognition of the causative drug is not possible. This study was aimed at evaluating the clinical features and culprit drugs in generalized fixed drug eruptions in the west of Iran.Method.This cross-sectional study was carried out on 30 patients with criteria of generalized fixed drug eruption over 9 years. Demographic, clinical, and drug intake information were collected.Results.Out of 30 patients (17 females and 13 males) with the mean age of26.67±10.21years, 28 (93.3%) and 2 (6.7%) cases had plaque and bullous clinical presentation, respectively. Upper limbs were the most common (90%) site of involvement. The antibiotic group, especially cotrimoxazole (26.1%), was reported to be the most common offending drug, but the causative drug was not determined in 7 (23.3%) patients.Conclusion.Many cases of generalized fixed drug eruption firstly presented as limited lesions and led to generalized lesion due to repeated intake of the causative drug. No causative drug was found in some patients, which might be associated with concurrent intake of several drugs, multiple FDE, and peculiarity of the patch test.


2014 ◽  
Vol 6 (5) ◽  
pp. 415 ◽  
Author(s):  
Jae-Woo Jung ◽  
Sang-Heon Cho ◽  
Kyu-Han Kim ◽  
Kyung-Up Min ◽  
Hye-Ryun Kang

1970 ◽  
Vol 101 (5) ◽  
pp. 621b-621 ◽  
Author(s):  
M. B. Brodin

2000 ◽  
Vol 62 (3) ◽  
pp. 343-345
Author(s):  
Kaoru MURATA ◽  
Atsushi HATAMOCHI ◽  
Hiroshi SHINKAI

2005 ◽  
Vol 67 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Yumiko KUBOTA ◽  
Juichiro NAKAYAMA

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