Piroxicam‐induced fixed drug eruption: Cross‐reactivity with meloxicam

2019 ◽  
Vol 81 (1) ◽  
pp. 24-26 ◽  
Author(s):  
Haifa Ben Romdhane ◽  
Helmi Ammar ◽  
Najeh Ben Fadhel ◽  
Zohra Chadli ◽  
Nadia Ben Fredj ◽  
...  
Keyword(s):  
Drug Eruption ◽  
Cross Reactivity ◽  
Fixed Drug Eruption ◽  
Fixed Drug

scholarly journals Desquamating Nonpigmenting Fixed Drug Eruption With Onycholysis due to Amoxicillin in a Child: Cross-reactivity Study

2020 ◽  
Vol 30 (2) ◽  
pp. 149-151 ◽  
Author(s):  
B Moya ◽  
A Vera ◽  
R Bazire ◽  
D Betancor ◽  
P Rodríguez Del Río ◽  
...  
Keyword(s):  
Drug Eruption ◽  
Cross Reactivity ◽  
Fixed Drug Eruption ◽  
Fixed Drug ◽  
Reactivity Study

scholarly journals Fixed drug eruption (FDE) induced by mefenamic acid with unusually cross‐reactivity to diclofenac: A case report

2020 ◽  
Author(s):  
Bouraoui Ouni ◽  
Neila Fathallah ◽  
Nesrine Ben‐Sayed ◽  
Nihed Abdessayed ◽  
Raoudha Slim ◽  
...  
Keyword(s):  
Case Report ◽  
Mefenamic Acid ◽  
Drug Eruption ◽  
Cross Reactivity ◽  
Fixed Drug Eruption ◽  
Fixed Drug

Naproxen-induced fixed drug eruption: A case report

2011 ◽  
Vol 30 (11) ◽  
pp. 1872-1874 ◽  
Author(s):  
Hikmet Akyazi ◽  
Davut Baltaci ◽  
Sevdegul Mungan ◽  
Ismail Hamdi Kara
Keyword(s):  
Propionic Acid ◽  
Side Effect ◽  
Drug Eruption ◽  
Symptomatic Relief ◽  
Provocation Test ◽  
Cross Reactivity ◽  
Common Side Effect ◽  
Fixed Drug Eruption ◽  
Fixed Drug ◽  
Oral Provocation Test

Naproxen is a non-steroidal anti-inflammatory drug (NSAID) widely used for symptomatic relief of arthritis and other painful disorders, such as dysmenorrheal. Pruritus is the most common side effect of naproxen. Fixed drug eruption (FDE) due to naproxen is a rarely reported side-effect. No previous report has declared cross-reactivity between naproxen and other propionic acid derivatives. A 28-year-old man, presented with edematous and erythematous patchy lesion along with pruritus and inflammation on lip, have been suffering since 3 hours. It started after taking naproxen 550 mg for headache. On detailed inquiry, he defined similar symptom which recurred after whenever he took naproxen. Based on clinical and histopathological findings, it is evaluated as naproxen-induced FDE. We have tested cross-reactivity between naproxen and other propionic acid derivatives, and then we obtained negative result for oral provocation test with flurbiprofen. Here, we present a case of naproxen-induced FDE of 28-year-old man, by overviewing literatures.

Fixed drug eruption due to norfloxacin and cross-reactivity with other quinolones

2013 ◽  
Vol 41 (1) ◽  
pp. 60-61 ◽  
Author(s):  
L. Sánchez-Morillas ◽  
P. Rojas Pérez-Ezquerra ◽  
M.L. González Morales ◽  
C. Mayorga ◽  
R. González-Mendiola ◽  
...  
Keyword(s):  
Drug Eruption ◽  
Cross Reactivity ◽  
Fixed Drug Eruption ◽  
Fixed Drug

scholarly journals Fixed Drug Eruption: A Rare Case of Polysensitivity between Two Unrelated Fixed Dose Combination Preparations - A Case Report

2020 ◽  
Author(s):  
Jessica Kaushal ◽  
Abhimanyu Rakesh
Keyword(s):  
Drug Eruption ◽  
Cross Reactivity ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Fixed Drug Eruption ◽  
Chemical Structures ◽  
Type Iv ◽  
Fixed Drug ◽  
Dose Combination ◽  
High Index Of Suspicion

Background: A fixed drug eruption is a type IV hypersensitivity reaction to a medication that characteristically re-emerges on the same site each time the specific drug is taken. Antimicrobials (including fixed dose combinations) are frequently implicated in fixed drug eruption while gliptins (as separate drugs or as combined preparations) on the other hand are infrequent triggers. Drugs belonging to similar classification and having similar chemical structures can show cross reactivity, but here we describe a case of cross reactivity between unrelated drug classes, also known as polysensitivity. The Case: A 58-year-old man presented with painful, burning, and pruritic blisters with ulcerations on the oral mucosa of lips, hard palate, and tip of the tongue. The patient had been on vildagliptin - metformin fixed dose combination tablets for one year. He was asked to stop the drug and lesions started improving thereafter. A week later he suffered from gastroenteritis for which he took a combined preparation of ofloxacin and ornidazole and lesions re-appeared at the same site as before with severe itching and burning. Conclusion: This case highlights polysensitivity amongst chemically unrelated drugs, especially available in fixed-dose combination. It is an extremely rare occurrence (less than 0.2%). Moreover, there have only been a few cases of such delayed reactions occurring to gliptins, especially vildagliptin. A clinician must keep a high index of suspicion to identify this phenomenon.

scholarly journals Generalized bullous fixed drug eruption to fluconazole; with cross-reactivity to tinidazole

2019 ◽  
Vol 64 (4) ◽  
pp. 335 ◽  
Author(s):  
PrachiV Gole ◽  
HershadaS Mithari ◽  
VidyaD Kharkar ◽  
SunandaA Mahajan
Keyword(s):  
Drug Eruption ◽  
Cross Reactivity ◽  
Fixed Drug Eruption ◽  
Fixed Drug

Fixed Drug Eruption and Cross-reactivity Between Tinidazole and Metronidazole

1990 ◽  
Vol 29 (10) ◽  
pp. 740-740 ◽  
Author(s):  
Devesh Mishra ◽  
M. Mobashir ◽  
M. Shoaib Zaheer
Keyword(s):  
Drug Eruption ◽  
Cross Reactivity ◽  
Fixed Drug Eruption ◽  
Fixed Drug

Fixed Drug Eruption to Rofecoxib with Cross-Reactivity to Sulfonamides

Dermatology ◽  
2001 ◽  
Vol 203 (4) ◽  
pp. 351-351 ◽  
Author(s):  
Charandeep Kaur ◽  
Rashmi Sarkar ◽  
Amrinder J. Kanwar
Keyword(s):  
Drug Eruption ◽  
Cross Reactivity ◽  
Fixed Drug Eruption ◽  
Fixed Drug
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