Acute generalized exanthematous pustulosis caused by an iodinated contrast radiocontrast medium for computed tomography arthrography of the knee

2017 ◽  
Vol 76 (6) ◽  
pp. 371-373 ◽  
Author(s):  
Charles Velter ◽  
Catherine Schissler ◽  
Chloé Moulinas ◽  
Martine Tebacher-Alt ◽  
Jean-Marie Siedel ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Acute Generalized Exanthematous Pustulosis ◽  
Iodinated Contrast ◽  
Exanthematous Pustulosis ◽  
Radiocontrast Medium

scholarly journals Iohexol-Induced Acute Generalized Exanthematous Pustulosis (AGEP): Case Report

2019 ◽  
Vol 3 (5) ◽  
pp. 358-361
Author(s):  
Irina Lerman ◽  
William H. Sipprell ◽  
Glynis A. Scott ◽  
Christopher T. Richardson
Keyword(s):  
Cell Lymphoma ◽  
Contrast Administration ◽  
Acute Generalized Exanthematous Pustulosis ◽  
Iodinated Contrast ◽  
History Of ◽  
Cutaneous Reactions ◽  
Dermal Infiltrate ◽  
Erythematous Plaques ◽  
Exanthematous Pustulosis ◽  
Contrast Allergy

Acute generalized exanthematous pustulosis (AGEP) is a rare adverse drug reaction characterized by numerous non-follicular sterile pustules overlying edematous, erythematous plaques. The majority of AGEP cases are associated with antimicrobial medications, although other agents and etiologies have also been implicated. Here, we report a patient with recurrent angioimmunoblastic T-cell lymphoma (AITL) who presented with a pruritic and widespread pustular eruption one week following computed tomography (CT) with iohexol contrast administration. Notably, she had a documented prior mild reaction to contrast medium and was appropriately pre-medicated with diphenhydramine and prednisone before imaging. Biopsy revealed intra-epidermal pustules, epidermal spongiosis, and dermal infiltrate of lymphocytes, neutrophils, and some eosinophils – histological findings consistent with AGEP. Systemic and topical corticosteroids plus topical mupirocin resulted in complete resolution of symptoms. While cutaneous reactions to iodinated contrast are common and often self-limited, severe manifestations such as AGEP must be considered particularly in patients with a history of prior contrast allergy.

Enzalutamide induced acute generalized exanthematous pustulosis

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Chloé Alberto ◽  
Maria Polina Konstantinou ◽  
Catherine Martinage ◽  
Eline Casassa ◽  
Emilie Tournier ◽  
...  
Keyword(s):  
Acute Generalized Exanthematous Pustulosis ◽  
Exanthematous Pustulosis

A Case of Acute Generalized Exanthematous Pustulosis in a Puerpera.

2000 ◽  
Vol 62 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Maiko YOKOYAMA ◽  
Tatsuro TANAKA ◽  
Yutaka NARISAWA
Keyword(s):  
Acute Generalized Exanthematous Pustulosis ◽  
Exanthematous Pustulosis

Nonionic Low-Osmolar Monomeric Iodinated Contrast Material: Some Aspects of use for Computed Tomography in Children

2017 ◽  
pp. 118-129
Author(s):  
I. A. Kondrashov ◽  
V. Mandal
Keyword(s):  
Computed Tomography ◽  
Contrast Agents ◽  
Adverse Reactions ◽  
Contrast Material ◽  
Iodine Content ◽  
Diagnostic Procedures ◽  
Diagnostic Efficacy ◽  
Minimum Risk ◽  
Electrical Neutrality ◽  
Iodinated Contrast

Iodine containing contrast media are used much frequently now-a-days for computed tomography examinations in children. The group of non-ionic monomers occupies a special place among modern contrast agents. Low osmolarity and viscosity, electrical neutrality and the highest iodine content of these contrast materials provide the best diagnostic efficacy with minimum risk of adverse reactions. However, characteristic anatomic and physiological aspects of a growing child’s body require additional attention and care during diagnostic procedures with use of such contrast agents. This article presents concise literature review of recent years highlighting practical aspects of nonionic lowosmolar iodinated contrast material use for computed tomography assisted diagnostic examinations in child population.

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