scholarly journals Cochlear implant performance in children deafened by congenital cytomegalovirus-A systematic review

2018 ◽  
Vol 43 (5) ◽  
pp. 1283-1295 ◽  
Author(s):  
V.J.C. Kraaijenga ◽  
F. Van Houwelingen ◽  
S.F. Van der Horst ◽  
J. Visscher ◽  
J.M.L. Huisman ◽  
...  
2011 ◽  
Vol 19 (6) ◽  
pp. 549-553 ◽  
Author(s):  
Mariane Perin da Silva ◽  
Ademir Antonio Comerlatto Junior ◽  
Maria Cecília Bevilacqua ◽  
Simone Aparecida Lopes-Herrera

2019 ◽  
Vol 62 (5) ◽  
pp. 1574-1593 ◽  
Author(s):  
Hanin Rayes ◽  
Ghada Al-Malky ◽  
Deborah Vickers

Objective The purpose of this systematic review is to evaluate the published research in auditory training (AT) for pediatric cochlear implant (CI) recipients. This review investigates whether AT in children with CIs leads to improvements in speech and language development, cognition, and/or quality of life and whether improvements, if any, remain over time post AT intervention. Method A systematic search of 7 databases identified 96 review articles published up until January 2017, 9 of which met the inclusion criteria. Data were extracted and independently assessed for risk of bias and quality of study against a PICOS (participants, intervention, control, outcomes, and study) framework. Results All studies reported improvements in trained AT tasks, including speech discrimination/identification and working memory. Retention of improvements over time was found whenever it was assessed. Transfer of learning was measured in 4 of 6 studies, which assessed generalization. Quality of life was not assessed. Overall, evidence for the included studies was deemed to be of low quality. Conclusion Benefits of AT were illustrated through the improvement in trained tasks, and this was observed in all reviewed studies. Transfer of improvement to other domains and also retention of benefits post AT were evident when assessed, although rarely done. However, higher quality evidence to further examine outcomes of AT in pediatric CI recipients is needed.


Author(s):  
Daniela Malta de Souza Medved ◽  
Larissa Mendes da Rocha Cavalheri ◽  
Ana Cristina Coelho ◽  
Ana Carolina Nascimento Fernandes ◽  
Eduardo Magalhães da Silva ◽  
...  

Vaccines ◽  
2019 ◽  
Vol 7 (4) ◽  
pp. 129 ◽  
Author(s):  
Coppola ◽  
Mangold ◽  
Cantrell ◽  
Permar

Congenital cytomegalovirus (cCMV) is the leading non-genetic cause of sensorineural hearing loss (SNHL), and efforts are geared towards prevention through vaccine development. Transmission rates following primary maternal infection occur at rates of 30–40%, however reported placental rates upon non-primary maternal infection is reported to be less than <4%. There is significant debate about whether this reduction in transmission rate is due to pre-existing maternal immunity, which could identify possible immunologic targets for vaccines. To address this question, we performed a systemic review of the literature using Preferred Reporting Items for Systematic Review and Analysis (PRISMA) guidelines. We identified cohort studies in high CMV seroprevalent (>80%) areas or in developing regions that examined a cohort of at least 50 infants for congenital CMV acquisition. We identified 19 articles that met criteria and were further categorized based on pre-conception serology, maternal seroprevalence, or previously known seroprevalence. Birth prevalence rates ranged from 0.4% to 6% (median 1.1%), with the studies reporting on clinical outcome (16/19 studies) noting the majority of infected infants as asymptomatic. We also utilized a recent study that differentiated primary maternal infections from chronic infections in a highly seropositive population to calculate a placental transmission rate in women with pre-existing immunity compared to that of no pre-existing immunity. This work confirms a low cCMV birth prevalence in highly seropositive populations, indicates via a calculated placental transmission rate that the CMV placental transmission rate is lower in non-primary infection than that of primary infection, and reveals gaps in data for further research aiming to identify targets for vaccine development.


2013 ◽  
Vol 79 (3) ◽  
pp. 382-390 ◽  
Author(s):  
Marina Morettin ◽  
Maria Jaquelini Dias dos Santos ◽  
Marcela Rosolen Stefanini ◽  
Fernanda de Lourdes Antonio ◽  
Maria Cecília Bevilacqua ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document