scholarly journals Trans-oral robotic assisted tongue base mucosectomy for investigation of cancer of unknown primary in the head and neck region. The UK experience

2017 ◽  
Vol 42 (6) ◽  
pp. 1247-1251 ◽  
Author(s):  
S.C. Winter ◽  
E. Ofo ◽  
D. Meikle ◽  
P. Silva ◽  
L. Fraser ◽  
...  
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Cancer Of Unknown Primary ◽  
Tongue Base ◽  
Unknown Primary ◽  
Head And Neck Region ◽  
Robotic Assisted ◽  
The Uk

scholarly journals A Systematic Review of Cancer of Unknown Primary in the Head and Neck Region

2021 ◽  
Vol Volume 13 ◽  
pp. 7235-7241
Author(s):  
Milosz Pinkiewicz ◽  
Karolina Dorobisz ◽  
Tomasz Zatoński
Keyword(s):  
Systematic Review ◽  
Head And Neck ◽  
Neck Region ◽  
Cancer Of Unknown Primary ◽  
Unknown Primary ◽  
Head And Neck Region

scholarly journals Human papillomavirus and p53 expression in cancer of unknown primary in the head and neck region in relation to clinical outcome

2014 ◽  
Vol 3 (2) ◽  
pp. 376-384 ◽  
Author(s):  
Lars Sivars ◽  
Anders Näsman ◽  
Nikolaos Tertipis ◽  
Andrea Vlastos ◽  
Torbjörn Ramqvist ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Clinical Outcome ◽  
Head And Neck ◽  
Neck Region ◽  
Cancer Of Unknown Primary ◽  
Unknown Primary ◽  
P53 Expression ◽  
Head And Neck Region

scholarly journals Carcinoma of Unknown Primary in Head and Neck Region

2018 ◽  
Vol 31 (4) ◽  
Author(s):  
Barbora Uhliarová ◽  
Marcela Navrátilová ◽  
Vladimír Čalkovský ◽  
Andrej Hajtman
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Unknown Primary ◽  
Head And Neck Region ◽  
Carcinoma Of Unknown Primary

scholarly journals Rhabdomyoma of the tongue base

2019 ◽  
Vol 5 (6) ◽  
pp. 1705
Author(s):  
Julius M. Vahl ◽  
Lisa Baumann ◽  
Thomas K. Hoffmann
Keyword(s):  
Head And Neck ◽  
Treatment Options ◽  
Neck Region ◽  
Rare Condition ◽  
Tongue Base ◽  
Medical Emergency ◽  
Head And Neck Region ◽  
Neck Tumors ◽  
Diagnostic Work ◽  
Work Up

<p class="abstract">Extracardiac rhabdomyoma is a very rare condition with potentially multifocal manifestations including the head and neck region. We present a case of an 81-year-old patient who presented as a medical emergency because of ambiguous, progressive throat pain and dysphagia. After diagnostic work up including magnetic resonance (MR) scan and biopsy a rhabdomyoma of the tongue base was diagnosed. The tumor was completely excised by transoral laser microsurgery and the patient’s symptoms vanished. This case report is described in context of the current literature with a discussion of diagnostic steps and treatment options of rhabdomyoma in the head and neck region. Rhabdomyoma is a rare, but nevertheless relevant differential diagnosis of head and neck tumors.</p>

scholarly journals Swedish National Multicenter Study on Head and Neck Cancer of Unknown Primary: Prognostic Factors and Impact of Treatment on Survival

2020 ◽  
Author(s):  
Lars Axelsson ◽  
Erik Holmberg ◽  
Jan Nyman ◽  
Anders Högmo ◽  
Helena Sjödin ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Prognostic Factors ◽  
Head And Neck ◽  
Neck Dissection ◽  
Neck Cancer ◽  
Multicenter Study ◽  
Performance Status ◽  
Cancer Of Unknown Primary ◽  
Unknown Primary ◽  
N Stage

Abstract Introduction Head and neck cancer of unknown primary (HNCUP) is a rare condition whose prognostic factors that are significant for survival vary between studies. No randomized treatment study has been performed thus far, and the optimal treatment is not established. Objective The present study aimed to explore various prognostic factors and compare the two main treatments for HNCUP: neck dissection and (chemo) radiation vs primary (chemo) radiation. Methods A national multicenter study was performed with data from the Swedish Head and Neck Cancer Register (SweHNCR) and from the patients' medical records from 2008 to 2012. Results Two-hundred and sixty HNCUP patients were included. The tumors were HPV-positive in 80%. The overall 5-year survival rate of patients treated with curative intent was 71%. Age (p < 0.001), performance status (p= 0.036), and N stage (p= 0.046) were significant factors for overall survival according to the multivariable analysis. Treatment with neck dissection and (chemo) radiation (122 patients) gave an overall 5-year survival of 73%, and treatment with primary (chemo) radiation (87 patients) gave an overall 5-year survival of 71%, with no significant difference in overall or disease-free survival between the 2 groups. Conclusions Age, performance status, and N stage were significant prognostic factors. Treatment with neck dissection and (chemo) radiation and primary (chemo) radiation gave similar survival outcomes. A randomized treatment study that includes quality of life is needed to establish the optimal treatment.

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