scholarly journals Long noncoding RNA LINC00152 is a potential prognostic biomarker in patients with high-grade glioma

2018 ◽  
Vol 24 (10) ◽  
pp. 957-966 ◽  
Author(s):  
Wen Wang ◽  
Fan Wu ◽  
Zheng Zhao ◽  
Kuan-Yu Wang ◽  
Ruo-Yu Huang ◽  
...  
2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Rui Zhao ◽  
Yanli Zhang ◽  
Xin Zhang ◽  
Yongmei Yang ◽  
Xin Zheng ◽  
...  

2019 ◽  
Vol 215 (11) ◽  
pp. 152649 ◽  
Author(s):  
Yoo Jin Lee ◽  
Harim Oh ◽  
Eojin Kim ◽  
Bokyung Ahn ◽  
Jeong Hyeon Lee ◽  
...  

2020 ◽  
Vol 16 (25) ◽  
pp. 1911-1920
Author(s):  
Feifei Chu ◽  
Yuanbo Cui ◽  
Kunkun Li ◽  
Xingguo Xiao ◽  
Li Zhang ◽  
...  

Aim: Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. This study aimed to investigate the role of long noncoding RNA THOR in CRC. Materials & methods: The expression of THOR in 103 cases of CRC tissues and four CRC cell lines was examined by quantitative real-time PCR. Cell counting kit-8 and colony formation assays were applied to detect cell proliferation, and flow cytometry was used for testing cell cycle and apoptosis of CRC. Results: We found that THOR was highly expressed in CRC and correlated with tumor node metastasis stage, histological subtype, tumor size and differentiation and survival in CRC patients. Meanwhile, knockdown of THOR significantly suppressed cell proliferation and cell cycle of CRC, whereas promoted cell apoptosis. Conclusion: Our findings suggest that THOR is an oncogenic long noncoding RNA in CRC and a potential prognostic biomarker for this cancer.


2017 ◽  
Vol Volume 10 ◽  
pp. 2805-2813 ◽  
Author(s):  
Xiaohui Zhan ◽  
Chuanpeng Dong ◽  
Gang Liu ◽  
Yixue Li ◽  
Lei Liu

2017 ◽  
Vol 19 (suppl_6) ◽  
pp. vi92-vi92
Author(s):  
Sze Kiat Tan ◽  
Chiara Pastori ◽  
Clara Penas ◽  
Jann Sarkaria ◽  
Ricardo J Komotar ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document