The role of neuroinflammation and amyloid in cognitive impairment in an APP/PS1 transgenic mouse model of Alzheimer's disease

Shenghua Zhu; Junhui Wang; Yanbo Zhang; Jue He; Jiming Kong; Jun-Feng Wang; Xin-Min Li

doi:10.1111/cns.12677

The role of neuroinflammation and amyloid in cognitive impairment in an APP/PS1 transgenic mouse model of Alzheimer's disease

CNS Neuroscience & Therapeutics ◽

10.1111/cns.12677 ◽

2017 ◽

Vol 23 (4) ◽

pp. 310-320 ◽

Cited By ~ 24

Author(s):

Shenghua Zhu ◽

Junhui Wang ◽

Yanbo Zhang ◽

Jue He ◽

Jiming Kong ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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Isorhynchophylline ameliorates cognitive impairment via modulating amyloid pathology, tau hyperphosphorylation and neuroinflammation: Studies in a transgenic mouse model of Alzheimer’s disease

Brain Behavior and Immunity ◽

10.1016/j.bbi.2019.08.194 ◽

2019 ◽

Vol 82 ◽

pp. 264-278 ◽

Cited By ~ 6

Author(s):

Hui-Qin Li ◽

Siu-Po Ip ◽

Qiu-Ju Yuan ◽

Guo-Qing Zheng ◽

Karl K.W. Tsim ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Tau Hyperphosphorylation ◽

Amyloid Pathology ◽

Model Of Alzheimer’S Disease

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Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD)

Behavioural Brain Research ◽

10.1016/j.bbr.2015.04.028 ◽

2015 ◽

Vol 289 ◽

pp. 69-77 ◽

Cited By ~ 53

Author(s):

Akira Nakajima ◽

Yuki Aoyama ◽

Eun-Joo Shin ◽

Yunsung Nam ◽

Hyoung-Chun Kim ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease ◽

Triple Transgenic Mouse

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WBQ5187, a Multitarget Directed Agent, Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease and Modulates Cerebral β-Amyloid, Gliosis, cAMP Levels, and Neurodegeneration

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.9b00409 ◽

2019 ◽

Vol 10 (12) ◽

pp. 4787-4799

Author(s):

Zhiren Wang ◽

Mengru Cao ◽

Hongling Xiang ◽

Wei Wang ◽

Xing Feng ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease ◽

Β Amyloid ◽

Camp Levels

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Vasoactive effects of Aβin isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: Role of inflammation

Neurological Research ◽

10.1179/016164103101201940 ◽

2003 ◽

Vol 25 (6) ◽

pp. 642-651 ◽

Cited By ~ 84

Author(s):

Daniel Paris ◽

James Humphrey ◽

Amita Quadros ◽

Nikunj Patel ◽

Robert Crescentini ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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Subcutaneous Sustained-Release of Poly-Arginine Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease

Advances in Alzheimer s Disease ◽

10.4236/aad.2018.74011 ◽

2018 ◽

Vol 07 (04) ◽

pp. 153-182 ◽

Cited By ~ 4

Author(s):

Gennadiy Fonar ◽

Baruh Polis ◽

Tomer Meirson ◽

Alexander Maltsev ◽

Abraham O. Samson

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Sustained Release ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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Immunological alteration & toxic molecular inductions leading to cognitive impairment & neurotoxicity in transgenic mouse model of Alzheimer's disease

Life Sciences ◽

10.1016/j.lfs.2017.03.004 ◽

2017 ◽

Vol 177 ◽

pp. 49-59 ◽

Cited By ~ 7

Author(s):

Manuj Ahuja ◽

Manal Buabeid ◽

Engy Abdel-Rahman ◽

Mohammed Majrashi ◽

Kodeeswaran Parameshwaran ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease

Neuropsychopharmacology ◽

10.1038/npp.2014.164 ◽

2014 ◽

Vol 39 (13) ◽

pp. 2949-2962 ◽

Cited By ~ 122

Author(s):

Teng Jiang ◽

Lan Tan ◽

Xi-Chen Zhu ◽

Qiao-Quan Zhang ◽

Lei Cao ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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P3-396: NK-4, a photosensitizing cyanine dye, prevented beta-amyloid-induced cognitive impairment in a transgenic mouse model of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2010.05.1938 ◽

2010 ◽

Vol 6 ◽

pp. S568-S568

Author(s):

Hitomi Ohta ◽

Kenji Akita ◽

Shigeyuki Arai ◽

Tsunetaka Ohta ◽

Toshio Kawata ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Beta Amyloid ◽

Transgenic Mouse Model ◽

Cyanine Dye ◽

Model Of Alzheimer’S Disease

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P3-171: ROLE OF AKT-MTOR SIGNALING IN EARLY HIPPOCAMPAL DYSFUNCTION IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE

Alzheimer s & Dementia ◽

10.1016/j.jalz.2019.06.3200 ◽

2019 ◽

Vol 15 ◽

pp. P995-P996

Author(s):

Ruturaj Gowaikar ◽

Sunny Kumar ◽

Kunal Singh ◽

Latha Diwakar ◽

Smitha Karunakaran ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Mtor Signaling ◽

Hippocampal Dysfunction ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Preserved fronto-striatal plasticity and enhanced procedural learning in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020559.235469 ◽

2004 ◽

Author(s):

Karl-Peter Giese

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Procedural Learning ◽

Model Of Alzheimer’S Disease

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