scholarly journals Test-Retest Reliability of Graph Metrics in High-resolution Functional Connectomics: A Resting-State Functional MRI Study

2015 ◽  
Vol 21 (10) ◽  
pp. 802-816 ◽  
Author(s):  
Hai-Xiao Du ◽  
Xu-Hong Liao ◽  
Qi-Xiang Lin ◽  
Gu-Shu Li ◽  
Yu-Ze Chi ◽  
...  
NeuroImage ◽  
2013 ◽  
Vol 83 ◽  
pp. 969-982 ◽  
Author(s):  
Xu-Hong Liao ◽  
Ming-Rui Xia ◽  
Ting Xu ◽  
Zheng-Jia Dai ◽  
Xiao-Yan Cao ◽  
...  

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e72425 ◽  
Author(s):  
Haijing Niu ◽  
Zhen Li ◽  
Xuhong Liao ◽  
Jinhui Wang ◽  
Tengda Zhao ◽  
...  

2015 ◽  
Vol 253 ◽  
pp. 183-192 ◽  
Author(s):  
Martina Andellini ◽  
Vittorio Cannatà ◽  
Simone Gazzellini ◽  
Bruno Bernardi ◽  
Antonio Napolitano

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yanzhi Bi ◽  
Xin Hou ◽  
Jiahui Zhong ◽  
Li Hu

AbstractPain perception is a subjective experience and highly variable across time. Brain responses evoked by nociceptive stimuli are highly associated with pain perception and also showed considerable variability. To date, the test–retest reliability of laser-evoked pain perception and its associated brain responses across sessions remain unclear. Here, an experiment with a within-subject repeated-measures design was performed in 22 healthy volunteers. Radiant-heat laser stimuli were delivered on subjects’ left-hand dorsum in two sessions separated by 1–5 days. We observed that laser-evoked pain perception was significantly declined across sessions, coupled with decreased brain responses in the bilateral primary somatosensory cortex (S1), right primary motor cortex, supplementary motor area, and middle cingulate cortex. Intraclass correlation coefficients between the two sessions showed “fair” to “moderate” test–retest reliability for pain perception and brain responses. Additionally, we observed lower resting-state brain activity in the right S1 and lower resting-state functional connectivity between right S1 and dorsolateral prefrontal cortex in the second session than the first session. Altogether, being possibly influenced by changes of baseline mental state, laser-evoked pain perception and brain responses showed considerable across-session variability. This phenomenon should be considered when designing experiments for laboratory studies and evaluating pain abnormalities in clinical practice.


2021 ◽  
Author(s):  
Faezeh Vedaei ◽  
Mahdi Alizadeh ◽  
Victor M Romo ◽  
Feroze B. Mohamed ◽  
Chengyuan Wu

Abstract Resting-state functional magnetic resonance imaging (rs-fMRI) has been known as a powerful tool in neuroscience. However, exploring the test-retest reliability of the metrics derived from rs-fMRI BOLD signal is essential particularly in the studies of patients with neurological development. Two factors affecting reliability of rs-fMRI measurements including the effect of anesthesia and scan length have been estimated in this study. A total of 9 patients with drug-resistant epilepsy (DRE) of requiring interstitial thermal therapy (LITT) were scanned in two states of awake and under anesthesia. At each state, two rs-fMRI sessions were obtained that each one lasted 15 minutes, and the effect of scan length was evaluated. Voxel-wise rs-fMRI metrics including amplitude of low fractional frequency fluctuation (ALFF), amplitude of low fractional frequency fluctuation (fALFF), functional connectivity (FC), and regional homogeneity (ReHo) were measured. Intraclass correlation coefficient (ICC) was calculated to estimate the reliability between two sessions of scanning for both states. Overall, our finding revealed that reliability improves under anesthesia as well as by increasing the scanning length of the scanning sessions. Furthermore, we showed that the optimal scan length to achieve reliable rs-fMRI measurements was 3.1 – 7.5 minutes shorter in an anesthetized, compared to wakeful state.


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