Lipid domain association of influenza virus proteins detected by dynamic fluorescence microscopy techniques

2012 ◽  
Vol 15 (2) ◽  
pp. 179-189 ◽  
Author(s):  
Michael Veit ◽  
Stephanie Engel ◽  
Bastian Thaa ◽  
Silvia Scolari ◽  
Andreas Herrmann
Keyword(s):  
Influenza Virus ◽  
Fluorescence Microscopy ◽  
Lipid Domain ◽  
Microscopy Techniques ◽  
Dynamic Fluorescence ◽  
Virus Proteins

scholarly journals Newly Synthesized Influenza Virus Proteins are Transported from the Nucleus

1979 ◽  
Vol 45 (2) ◽  
pp. 527-532 ◽  
Author(s):  
J. W. F. Flawith ◽  
N. J. Dimmock
Keyword(s):  
Influenza Virus ◽  
Virus Proteins

Effect of Influenza Virus Proteins Modulate Hemostasis in vitro and in vivo

2003 ◽  
Vol 30 (6) ◽  
pp. 596-602
Author(s):  
I. N. Zhilinskaya ◽  
L. A. Lyapina ◽  
O. I. Kiselev ◽  
I. P. Ashmarin
Keyword(s):  
Influenza Virus ◽  
Virus Proteins

scholarly journals Transcranial in vivo detection of amyloid-beta at single plaque resolution with large-field multifocal illumination fluorescence microscopy

2020 ◽  
Author(s):  
Ruiqing Ni ◽  
Zhenyue Chen ◽  
Gloria Shi ◽  
Alessia Villois ◽  
Quanyu Zhou ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Fluorescence Microscopy ◽  
Amyloid Beta ◽  
Large Field ◽  
Microscopy Technique ◽  
In Vivo Detection ◽  
Amyloid Deposits ◽  
Microscopy Techniques

AbstractThe abnormal deposition of beta-amyloid proteins in the brain is one of the major histopathological hallmarks of Alzheimer’s disease. Currently available intravital microscopy techniques for high-resolution plaque visualization commonly involve highly invasive procedures and are limited to a small field-of-view within the rodent brain. Here, we report the transcranial detection of amyloid-beta deposits at the whole brain scale with 20 μm resolution in APP/PS1 and arcAβ mouse models of Alzheimer’s disease amyloidosis using a large-field multifocal (LMI) fluorescence microscopy technique. Highly sensitive and specific detection of amyloid-beta deposits at a single plaque level in APP/PS1 and arcAβ mice was facilitated using luminescent conjugated oligothiophene HS-169. Immunohistochemical staining with HS-169, anti-Aβ antibody 6E10, and conformation antibodies OC (fibrillar) of brain tissue sections further showed that HS-169 resolved compact parenchymal and vessel-associated amyloid deposits. The novel imaging platform offers new prospects for in vivo studies into Alzheimer’s disease mechanisms in animal models as well as longitudinal monitoring of therapeutic responses at a single plaque level.

Heterogeneity of milk fat globule membrane structure and composition as observed using fluorescence microscopy techniques

2008 ◽  
Vol 18 (12) ◽  
pp. 1081-1089 ◽  
Author(s):  
Jaap M. Evers ◽  
Richard G. Haverkamp ◽  
Stephen E. Holroyd ◽  
Geoffrey B. Jameson ◽  
Duncan D.S. Mackenzie ◽  
...  
Keyword(s):  
Fluorescence Microscopy ◽  
Milk Fat ◽  
Membrane Structure ◽  
Milk Fat Globule Membrane ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Microscopy Techniques
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