Computer-assisted template-guided custom-designed 3D-printed implant placement with custom-designed 3D-printed surgical tooling: an in-vitro proof of a novel concept

2016 ◽  
Vol 28 (5) ◽  
pp. 582-585 ◽  
Author(s):  
David Anssari Moin ◽  
Wiebe Derksen ◽  
Hugo Waars ◽  
Bassam Hassan ◽  
Daniel Wismeijer
Keyword(s):  
Computer Assisted ◽  
Implant Placement ◽  
3D Printed ◽  
Novel Concept

scholarly journals In Vitro Comparison between Metal Sleeve-Free and Metal Sleeve-Incorporated 3D-Printed Computer-Assisted Implant Surgical Guides

Materials ◽  
2021 ◽  
Vol 14 (3) ◽  
pp. 615
Author(s):  
Kyung Chul Oh ◽  
June-Sung Shim ◽  
Ji-Man Park
Keyword(s):  
Computer Assisted ◽  
Cross Sectional ◽  
Implant Placement ◽  
Surgical Guides ◽  
Measured Weight ◽  
Before And After ◽  
3D Printed ◽  
Student’S T ◽  
The Right

The present study aims to compare the accuracy of metal sleeve-free 3D-printed computer-assisted implant surgical guides (MSF group) (n = 10) with metal sleeve-incorporated 3D-printed computer-assisted implant surgical guides (MSI group) (n = 10). Implants of diameter 4.0 mm and 5.0 mm were placed in the left second premolars and bilateral first molars, respectively, using a fully guided system. Closed-form sleeves were used in teeth on the left and open-form sleeves on the right. The weight differences of the surgical guides before and after implant placement, and angular deviations before and after implant placement were measured. Weight differences were compared with Student’s t-tests and angular deviations with Mann–Whitney tests. Cross-sectional views of the insert parts were observed with a scanning electron microscope. Preoperative and postoperative weight differences between the two groups were not statistically significant (p = 0.821). In terms of angular deviations, those along the mesiodistal direction for the left second premolars were significantly lower in the MSF group (p = 0.006). However, those along the mesiodistal direction for the bilateral molars and those along the buccolingual direction for all teeth were not significantly different (p > 0.05). 3D-printed implant surgical guides without metal sleeve inserts enable accurate implant placement without exhausting the guide holes, rendering them feasible for fully guided implant placement.

scholarly journals Accuracy of Customized Prefabricated Screw-Type Immediate Provisional Restorations after Single-Implant Placement

2019 ◽  
Vol 8 (4) ◽  
pp. 490 ◽  
Author(s):  
Kyung Chul Oh ◽  
Jee-Hwan Kim ◽  
Chang-Woo Woo ◽  
Hong Seok Moon
Keyword(s):  
Computer Aided Design ◽  
Computer Assisted ◽  
Angular Deviation ◽  
Intraoral Scanner ◽  
Planning Stage ◽  
Implant Placement ◽  
Surgical Guides ◽  
Planning Software ◽  
Single Implant

Limited evidence is available comparing the differences between pre-operative and post-operative 3D implant positions from the viewpoint of prosthetics. We aimed to investigate the differences between preplanned positions of virtual provisional restorations and their actual positions following fully guided single-implant placement. Ten maxillary typodonts with missing right central incisors were imaged using cone-beam computed tomography, and digital impressions were obtained using an intraoral scanner. These data were imported into implant-planning software, following which the provisional restorations were designed. After data superimposition, an appropriate implant position was determined, and a computer-assisted implant surgical guide was designed for each typodont. Orders generated from the implant-planning software were imported into relevant computer-aided design software to design the custom abutments. The abutments, provisional restorations, and surgical guides were fabricated, and each restoration was cemented to the corresponding abutments, generating a screw-type immediate provisional restoration. The implants were placed using the surgical guides, and the screw-type provisional restorations were engaged to the implants. The typodonts were then rescanned using the intraoral scanner. The restorations designed at the treatment planning stage were compared with those in the post-operative scan using metrology software. The angular deviation around the central axis of the implant was measured, and the differences in the crown position were converted to root mean square (RMS) values. The post-operative provisional restorations exhibited an absolute angular deviation of 6.94 ± 5.78° and an RMS value of 85.8 ± 20.2 µm when compared with their positions in the pre-operative stage. Within the limitations of the present in vitro study, the results highlight the potential application of customized prefabricated immediate provisional restorations after single-implant placement.

scholarly journals 3D Printed Multi Functional Ti6Al4V Based Hybrid Scaffold for the Management of Osteosarcoma

2021 ◽  
Author(s):  
Bianyun Cai ◽  
Leizhen Huang ◽  
Jingcheng Wang ◽  
dan Sun ◽  
Ce zhu ◽  
...  
Keyword(s):  
Drug Release ◽  
Lattice Structure ◽  
Aqueous Dispersion ◽  
Deionized Water ◽  
Computer Assisted ◽  
Freeze Dried ◽  
Vis Spectroscopy ◽  
3D Printed

<p>2.1.1 Preparation of drug-laden Gel/HA composite</p> <p>Alendronate (ALN), is a commonly used bisphosphonate drug for osteoporosis management and bone regeneration. <sup>[33] </sup>However, direct loading of ALN onto Gel often results in burst drug release due to the fast Gel degradation <i>in vivo</i>. In contrast, degradable HA microsphere is an excellent drug delivery vehicle, which can provide sustained/controlled drug release as well as promoting osteoblasts mineralization/maturation (due to slow release of Ca<sup>2+</sup> and PO<sub>4</sub><sup>3-</sup>). <sup>[34]</sup> To prepare the ALN-laden HA microspheres/Gel composite (ALN-HA/Gel), HA microspheres were first synthesized following established procedure.<sup> [35]</sup> 0.5 g ALN was then added into 50 mL aqueous dispersion containing 2.0 g HA microspheres. After mixing using shaking incubator under 37 ℃ for 48 h, ALN-HA were collected by centrifugation and vacuum dried at 40 ℃ for 24 h. ALN concentration in the supernatant solution was evaluated by UV-vis spectroscopy. The drug-laden Gel/ALN-HA can be obtained by dispersing 3.0g ALN-HA microspheres in 50 mL deionized water, followed by addition of 8.0 g Gel, and stirred magnetically at 1000 rpm under 50 ℃ for 1 h.</p> <p>2.1.2 Preparation of 3D printed Ti6Al4V scaffolds</p> <p>3D printed Ti6Al4V scaffolds (named as Ti) were manufactured by electron beam melting (EBM) facility in-house. The lattice structure was designed by computer-assisted design (CAD) software (Magics, Materialise, Belgium) based on a dodecahedron unit cell with strut diameter of 300 μm and porosity of 80%. Cubic scaffolds (5mm × 5mm × 5mm) were used for <i>in vitro</i> testing and cylindrical scaffolds (Φ = 6mm, height = 6mm) were used for <i>in vivo</i> experiments. All samples were thoroughly cleaned by sonication in acetone, alcohol and deionized water for 30 min, respectively. The Ti scaffolds were subsequently subjected to hydrothermal treatment.<sup> [36]</sup> Specifically, the scaffolds were immersed in an aqueous solution (m(H<sub>2</sub>O<sub>2</sub>):m(H<sub>3</sub>PO<sub>4</sub>) 9:1) and placed in a Teflon-lined autoclave under 220 ℃ for 24 h. After the treatment, scaffolds were washed with distilled water and dried in air at room temperature for 24 h. The hydrothermally treated samples were named as HR-Ti.</p> <p>2.1.3 Preparation of Gel/ALN-HA infused HR-Ti scaffold</p> <p>The Gel/ALN-HA mixture was infused into the HR-Ti, then the infused scaffolds were held at -80<a> </a>℃ overnight followed by freeze-drying at -40 ℃ for 48 h. After that, the infused scaffolds were immersed in 100 mL ethanol containing 50mmol/L 1-ethyl-3-(3- (dimethylamino) propyl) carbodiimide hydrochlorid (EDC∙HCl) and N-hydroxysuccinimide (NHS) at 4 ℃ for 10 h to crosslink the Gel content. Afterwards, the scaffolds were washed three times by ethanol and freeze-dried again. The final scaffolds were named as Gel/ALN-HA/HR-Ti. For comparison, ALN/HR-Ti (without Gel and HA), Gel/ALN/HR-Ti (without HA) and Gel/HA/HR-Ti (without ALN) were also prepared.</p>

scholarly journals 3D Printed Multi Functional Ti6Al4V Based Hybrid Scaffold for the Management of Osteosarcoma

2021 ◽  
Author(s):  
Bianyun Cai ◽  
Leizhen Huang ◽  
Jingcheng Wang ◽  
dan Sun ◽  
Ce zhu ◽  
...  
Keyword(s):  
Drug Release ◽  
Lattice Structure ◽  
Aqueous Dispersion ◽  
Deionized Water ◽  
Computer Assisted ◽  
Freeze Dried ◽  
Vis Spectroscopy ◽  
3D Printed

<p>2.1.1 Preparation of drug-laden Gel/HA composite</p> <p>Alendronate (ALN), is a commonly used bisphosphonate drug for osteoporosis management and bone regeneration. <sup>[33] </sup>However, direct loading of ALN onto Gel often results in burst drug release due to the fast Gel degradation <i>in vivo</i>. In contrast, degradable HA microsphere is an excellent drug delivery vehicle, which can provide sustained/controlled drug release as well as promoting osteoblasts mineralization/maturation (due to slow release of Ca<sup>2+</sup> and PO<sub>4</sub><sup>3-</sup>). <sup>[34]</sup> To prepare the ALN-laden HA microspheres/Gel composite (ALN-HA/Gel), HA microspheres were first synthesized following established procedure.<sup> [35]</sup> 0.5 g ALN was then added into 50 mL aqueous dispersion containing 2.0 g HA microspheres. After mixing using shaking incubator under 37 ℃ for 48 h, ALN-HA were collected by centrifugation and vacuum dried at 40 ℃ for 24 h. ALN concentration in the supernatant solution was evaluated by UV-vis spectroscopy. The drug-laden Gel/ALN-HA can be obtained by dispersing 3.0g ALN-HA microspheres in 50 mL deionized water, followed by addition of 8.0 g Gel, and stirred magnetically at 1000 rpm under 50 ℃ for 1 h.</p> <p>2.1.2 Preparation of 3D printed Ti6Al4V scaffolds</p> <p>3D printed Ti6Al4V scaffolds (named as Ti) were manufactured by electron beam melting (EBM) facility in-house. The lattice structure was designed by computer-assisted design (CAD) software (Magics, Materialise, Belgium) based on a dodecahedron unit cell with strut diameter of 300 μm and porosity of 80%. Cubic scaffolds (5mm × 5mm × 5mm) were used for <i>in vitro</i> testing and cylindrical scaffolds (Φ = 6mm, height = 6mm) were used for <i>in vivo</i> experiments. All samples were thoroughly cleaned by sonication in acetone, alcohol and deionized water for 30 min, respectively. The Ti scaffolds were subsequently subjected to hydrothermal treatment.<sup> [36]</sup> Specifically, the scaffolds were immersed in an aqueous solution (m(H<sub>2</sub>O<sub>2</sub>):m(H<sub>3</sub>PO<sub>4</sub>) 9:1) and placed in a Teflon-lined autoclave under 220 ℃ for 24 h. After the treatment, scaffolds were washed with distilled water and dried in air at room temperature for 24 h. The hydrothermally treated samples were named as HR-Ti.</p> <p>2.1.3 Preparation of Gel/ALN-HA infused HR-Ti scaffold</p> <p>The Gel/ALN-HA mixture was infused into the HR-Ti, then the infused scaffolds were held at -80<a> </a>℃ overnight followed by freeze-drying at -40 ℃ for 48 h. After that, the infused scaffolds were immersed in 100 mL ethanol containing 50mmol/L 1-ethyl-3-(3- (dimethylamino) propyl) carbodiimide hydrochlorid (EDC∙HCl) and N-hydroxysuccinimide (NHS) at 4 ℃ for 10 h to crosslink the Gel content. Afterwards, the scaffolds were washed three times by ethanol and freeze-dried again. The final scaffolds were named as Gel/ALN-HA/HR-Ti. For comparison, ALN/HR-Ti (without Gel and HA), Gel/ALN/HR-Ti (without HA) and Gel/HA/HR-Ti (without ALN) were also prepared.</p>

Accuracy of Different Surgical Guide Designs for Static Computer-Assisted Implant Surgery: An in vitro Study

2021 ◽  
Author(s):  
Yu Tsung Wu ◽  
Panos Papaspyridakos ◽  
Kiho Kang ◽  
Matthew Finkelman ◽  
Yukio Kudara ◽  
...  
Keyword(s):  
In Vitro Study ◽  
Vitro Study ◽  
Computer Assisted ◽  
Surgical Guide ◽  
Implant Placement ◽  
Surgical Guides ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2

The aims of this study were to evaluate the effect of (i) the different surgical guide designs and (ii) implant placement location on the accuracy of fully guided implant placement in single edentulous sites using an in vitro study model. Forty-five partially edentulous models were scanned and divided into three groups: group 1, tooth-supported full-arch surgical guide; group 2, three different tooth-supported shortened surgical guides (SSGs); and group 3, tooth-supported full-arch surgical guide with a crossbar. All surgical guides were printed and used for fully guided implant placement. A total of 180 implants (60 per group) were placed, and scanbodies were positioned on all models, and postoperative surface scan files (STL) files were obtained. Superimposition of preoperative and postoperative STL files was performed, and the accuracy of implant position was evaluated. The interaction between group and implant location was statistically significant for angle, 3D offset at the base, and at the tip (p&lt;0.001). The post-hoc tests showed a statistically significantly higher deviation for group 2 compared to group 3 for all outcomes for implants #4 (p&lt;0.05) and #7 (p&lt;0.05). There was also a statistically significant difference in all outcomes between groups 1 and 3 for implant #7 (p&lt;0.05). All surgical guide designs presented satisfactory performance with clinically acceptable levels of deviation. However, SSGs presented higher accuracy for guided implant placement in a single-edentulous site, whereas a full-arch surgical guide with a crossbar presented superior outcomes when two or more guided implants were placed simultaneously.

Sign in / Sign up

Export Citation Format

Share Document