scholarly journals Efficacy of bone‐substitute materials use in immediate dental implant placement: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
John Zaki ◽  
Nermin Yusuf ◽  
Ahmed El‐Khadem ◽  
Rob J. P. M. Scholten ◽  
Kevin Jenniskens
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Bone Substitute ◽  
Meta Analysis ◽  
Implant Placement ◽  
Bone Substitute Materials ◽  
Substitute Materials

Are Subchondral Intraosseous Injections Effective and Safe for the Treatment of Knee Osteoarthritis? A Systematic Review

2019 ◽  
Vol 32 (11) ◽  
pp. 1046-1057 ◽  
Author(s):  
Kavin Sundaram ◽  
Juan S. Vargas-Hernández ◽  
Tomas Roca Sanchez ◽  
Nestor Moreno Moreu ◽  
Michael A. Mont ◽  
...  
Keyword(s):  
Systematic Review ◽  
Knee Osteoarthritis ◽  
Knee Arthroplasty ◽  
Bone Substitute ◽  
Knee Oa ◽  
Patient Reported ◽  
Intraosseous Injection ◽  
Bone Substitute Materials ◽  
Substitute Materials

AbstractKnee osteoarthritis (OA) is a highly prevalent disease and treatment options for early stages of OA are needed. Intraosseous injections of bone substitute and biologic materials have been proposed to expand the therapeutic arsenal by potentially halting OA progression and delaying the need for knee arthroplasty in patients with early/moderate-stage disease. Therefore, the goal of this study was assessed the efficacy and safety of subchondral intraosseous injection for the treatment of knee OA. A systematic review was performed on PubMed-Medline, and the Cochrane Database of systematic reviews. English and Spanish retrospective and prospective studies assessing the results of subchondral intraosseous injection of bone substitute materials and/or biologicals in human patients with knee OA, with a minimum of 6 months of follow-up were collected. A total of 1,081 potential articles were identified through our search. Six studies were included with a total of 163 patients. The mean follow-up was 18 months (range: 6–24 months). Patient reported outcomes measures (PROMs), complications, and conversion to total knee arthroplasty (TKA) were collected. All six studies showed PROMs improvement relative to baseline. Overall, the five studies reporting visual-analog scale (VAS) pain outcomes improved from a baseline mean score of 6.68 to 2.74. Also, knee injury and osteoarthritis score (KOOS), Tegner-Lysholm, and/or international knee documentation committee (IKDC) scores rose compared with baseline scores in all studies. Overall, 2.5% (4/163) of patients had a complication attributed to study-related treatment. Most patients (81%, 86/106) remained TKA-free at a 1-year follow-up. Subchondral intraosseous injections of bone substitute materials and platelet-rich plasma (PRP) suggest (1) improved PROMs of pain and functional status, (2) low complication rate, and (3) relatively low rates of conversion to TKA. However, the current studies investigating these treatments exhibited high degree of heterogeneity in both measurement of outcomes and delivery of treatment, with a high risk of bias. This procedure should not be utilized in advanced knee OA. In light of the limitations of the current literature, advising in favor or against this therapy for early to moderate knee OA is challenging.

scholarly journals Outcome of early dental implant placement versus other dental implant placement protocols: A systematic review and meta‐analysis

2018 ◽  
Vol 90 (5) ◽  
pp. 493-506 ◽  
Author(s):  
Seyed Hossein Bassir ◽  
Karim El Kholy ◽  
Chia‐Yu Chen ◽  
Kyu Ha Lee ◽  
Giuseppe Intini
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Meta Analysis ◽  
Implant Placement

scholarly journals Dental implants and risk of bleeding in patients on oral anticoagulants: a systematic review and meta-analysis

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Basim E. S. Dawoud ◽  
Samuel Kent ◽  
Oliver Tabbenor ◽  
Pynadath George ◽  
Jagtar Dhanda
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Meta Analysis ◽  
Bleeding Complications ◽  
Implant Surgery ◽  
Risk Of Bleeding ◽  
Implant Placement ◽  
Increased Risk ◽  
Dental Implant Surgery ◽  
Anticoagulated Patients

Abstract Background Dental implant placement is safe and predictable, yet optimal management of anticoagulated patients remains controversial. Whilst cessation of anticoagulation pre-operatively should decrease risks of bleeding, risk of thrombosis increases. We aim to define risk of bleeding in patients on oral anticoagulation who are undergoing dental implant placement, in order to establish best management. Methods This systematic review is registered with the National Institute for Health Research (NIHR) PROSPERO database (Registration No: CRD42021233929). We performed a systematic review as per Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance. Studies were identified using an agreed search strategy within the OVID Gateway (this included Pubmed, MEDLINE, Cochrane Collaborative). Studies assessing bleeding complications in patients who were undergoing dental implant placement were selected. The primary outcome was bleeding events in anticoagulated patients undergoing dental implant placement. Secondary outcomes included any complication requiring further intervention. Results We identified 182 studies through screening, and after review of titles and abstracts reduced this to 8 studies. In these studies, 1467 participants received at least 2366 implants. Studies were analysed for quality using the ROBINS-I risk of bias tool. Four studies were retrospective case reviews, and four were prospective reviews, three of which also blinded the operator to anticoagulation status. There was significant heterogeneity between the included studies. Meta-analysis showed an increased risk of bleeding (RR, 2.30; 95% CI, 1.25-4.24 p = 0.37 I = 7%) when implants were placed in the presence of anticoagulation however these were not clinically significant haemorrhagic events. Conclusion The continuation of anticoagulants peri-operatively during dental implant surgery does increase the risk of clinically non-significant peri- and post-operative bleeding. Dental implant surgery encompasses a broad spectrum of procedures ranging from minor to more invasive surgery with simple local haemostatic measures mitigating the risk of bleeding. The decision to discontinue anticoagulants prior to dental implant surgery must consider patient and surgical factors with the clinician undertaking a risk-balance assessment.

scholarly journals Antibiotic prophylaxis at dental implant placement: Which is the best protocol? A systematic review and network meta‐analysis

2019 ◽  
Vol 46 (3) ◽  
pp. 382-395 ◽  
Author(s):  
Mario Romandini ◽  
Ilaria De Tullio ◽  
Francesca Congedi ◽  
Zamira Kalemaj ◽  
Mattia D‘Ambrosio ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antibiotic Prophylaxis ◽  
Dental Implant ◽  
Meta Analysis ◽  
Implant Placement

scholarly journals Failure Rate, Marginal Bone Loss and Pink Esthetic of Socket-Shield Technique for Immediate Dental Implant Placement in the Esthetic Zone. A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Alvaro Zubizarreta Macho ◽  
Roberta Rucco ◽  
Sergio Toledano Gil ◽  
Juan Carlos Bernabeu Mira ◽  
Jose María Montiel-Company ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Loss ◽  
Dental Implant ◽  
Failure Rate ◽  
Meta Analysis ◽  
Marginal Bone Loss ◽  
Implant Placement

scholarly journals Efficacy of lateral bone augmentation performed simultaneously with dental implant placement: A systematic review and meta-analysis

2019 ◽  
Vol 46 ◽  
pp. 257-276 ◽  
Author(s):  
Daniel S. Thoma ◽  
Stefan P. Bienz ◽  
Elena Figuero ◽  
Ronald E. Jung ◽  
Ignacio Sanz-Martín
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Meta Analysis ◽  
Bone Augmentation ◽  
Implant Placement
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