Guided bone regeneration with recombinant human bone morphogenetic protein 9 loaded on either deproteinized bovine bone mineral or a collagen barrier membrane

2017 ◽  
Vol 19 (4) ◽  
pp. 600-607 ◽  
Author(s):  
Nikola Saulacic ◽  
Masako Fujioka-Kobayashi ◽  
Eizaburo Kobayashi ◽  
Benoit Schaller ◽  
Richard J. Miron
2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Dong-Yeol Lee ◽  
Hyo-Won Ahn ◽  
Yeek Herr ◽  
Young-Hyuk Kwon ◽  
Seong-Hun Kim ◽  
...  

This prospective randomized split-mouth study was performed to examine the effects of absorbable collagen membrane (ACM) application in augmented corticotomy using deproteinized bovine bone mineral (DBBM), during orthodontic buccal tipping movement in the dog. After buccal circumscribing corticotomy and DBBM grafting into the decorticated area, flaps were repositioned and sutured on control sides. ACM was overlaid and secured with membrane tacks, on test sides only, and the flaps were repositioned and sutured. Closed coil springs were used to apply 200 g orthodontic force in the buccolingual direction on the second and third premolars, immediately after primary flap closure. The buccal tipping angles were31.19±14.60° and28.12±11.48° on the control and test sides, respectively. A mean of79.5 ± 16.0% of the buccal bone wall was replaced by new bone on the control side, and on the test side78.9±19.5% was replaced. ACM application promoted an even bone surface. In conclusion, ACM application in augmented corticotomy using DBBM might stimulate periodontal tissue reestablishment, which is useful for rapid orthodontic treatment or guided bone regeneration. In particular, ACM could control the formation of mesenchymal matrix, facilitating an even bone surface.


2013 ◽  
Vol 25 (7) ◽  
pp. 786-790 ◽  
Author(s):  
Jan Lindhe ◽  
Denis Cecchinato ◽  
Mauro Donati ◽  
Cristiano Tomasi ◽  
Birgitta Liljenberg

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