scholarly journals Monolithic implant-supported lithium disilicate (LS2) crowns in a complete digital workflow: A prospective clinical trial with a 2-year follow-up

2017 ◽  
Vol 19 (3) ◽  
pp. 505-511 ◽  
Author(s):  
Tim Joda ◽  
Marco Ferrari ◽  
Urs Brägger
Keyword(s):  
Clinical Trial ◽  
Lithium Disilicate ◽  
Prospective Clinical Trial ◽  
Digital Workflow

scholarly journals Prospective Clinical Trial of Robotically Assisted Endoscopic Coronary Grafting With 1-Year Follow-Up

2001 ◽  
Vol 233 (6) ◽  
pp. 725-732 ◽  
Author(s):  
Sunil M. Prasad ◽  
Christopher T. Ducko ◽  
Edward R. Stephenson ◽  
Charles E. Chambers ◽  
and Ralph J. Damiano
Keyword(s):  
Clinical Trial ◽  
Prospective Clinical Trial

Twenty-Year Follow-Up of a Randomized Prospective Clinical Trial of Excimer Laser Photorefractive Keratectomy

2014 ◽  
Vol 158 (4) ◽  
pp. 651-663.e1 ◽  
Author(s):  
David P.S. O’Brart ◽  
Zaid Shalchi ◽  
Robert J. McDonald ◽  
Parul Patel ◽  
Timothy J. Archer ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Excimer Laser ◽  
Prospective Clinical Trial ◽  
Photorefractive Keratectomy

scholarly journals Effect of Balloon Eustachian Tuboplasty in Adults That Only Have Symptoms of Chronic Eustachian Tube Dysfunction, With a 1-Year Follow-Up: Prospective Clinical Trial

2020 ◽  
pp. 014556132098019
Author(s):  
Martin Formánek ◽  
Debora Formánková ◽  
Lukáš Školoudík ◽  
Karol Zeleník ◽  
Viktor Chrobok ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Eustachian Tube ◽  
Pure Tone Audiometry ◽  
Adult Patients ◽  
Eustachian Tube Dysfunction ◽  
Prospective Clinical Trial ◽  
Patient Reported ◽  
Tube Dysfunction ◽  
Balloon Eustachian Tuboplasty

Objectives: Balloon eustachian tuboplasty (BET) is a promising therapeutic option for eustachian tube (ET) dysfunction. However, data are lacking on the effect of BET in adults with symptoms of chronic ET dysfunction but without a contributing pathology. This study investigated the effect of BET in adult patients with only symptoms of chronic ET dysfunction. Methods: This prospective clinical trial included adult patients with aerated physiological middle ears and symptoms of ET dysfunction for more than 6 months. Compliance with follow-up was 93.3%. We evaluated the effects of BET with tympanometry, assessment of the Valsalva or Toynbee maneuver with tympanometry verification, a Eustachian Tube Dysfunction Questionnaire (ETDQ-7), and pure-tone audiometry. Data were recorded 1 day before surgery and 2, 6, and 12 months after BET. Therapy was considered successful when the patient exhibited a newly acquired ability to perform the Valsalva or Toynbee maneuver or when the ETDQ-7 score improved by 20% or more. Results: We included 14 ears in the analysis. After 2, 6, and 12 months, therapy was successful, according to the ETDQ-7, in 11/14 (78.6%; 95% CI: 48.8-94.3), 13/14 (92.9%; 95% CI: 64.2-99.6), and 12/14 (85.7%; 95% CI: 56.2-97.5) ears, respectively. These results were statistically significant. The ETDQ-7 scores also significantly decreased at 2, 6, and 12 months after the BET, when any change was observed. All patients experienced improvement. Only 1 patient reported temporary deterioration after 2 months. Treatment was more frequently successful in patients without nasal polyps or pollinosis. Conclusions: Adults with only symptoms of chronic ET dysfunction benefitted more and had longer lasting results from BET, compared to patients with pathologies caused by ET dysfunction. Balloon eustachian tuboplasty could be recommended for these patients.

scholarly journals Two-Year Follow-Up of a Prospective Clinical Trial of Cyclosporine for Frequently Relapsing Nephrotic Syndrome in Children

2012 ◽  
Vol 7 (10) ◽  
pp. 1576-1583 ◽  
Author(s):  
Kenji Ishikura ◽  
Norishige Yoshikawa ◽  
Hitoshi Nakazato ◽  
Satoshi Sasaki ◽  
Kazumoto Iijima ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Nephrotic Syndrome ◽  
Prospective Clinical Trial ◽  
Frequently Relapsing Nephrotic Syndrome
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