Appropriate Use and Clinical Impact of Echocardiographic “Evaluation of Murmur” in Pediatric Patients

2016 ◽  
Vol 11 (6) ◽  
pp. 721-726 ◽  
Author(s):  
Kirsten Rose-Felker ◽  
Michael S. Kelleman ◽  
Robert M. Campbell ◽  
Matthew E. Oster ◽  
Ritu Sachdeva
2015 ◽  
Vol 31 (3) ◽  
pp. 521-528 ◽  
Author(s):  
Thomas P. Koshy ◽  
Anand Rohatgi ◽  
Sandeep R. Das ◽  
Angela L. Price ◽  
Andres deLuna ◽  
...  

2019 ◽  
Vol 6 ◽  
pp. 2329048X1983047
Author(s):  
Edward B. Clark ◽  
Russell J. Butterfield ◽  
Francis M. Filloux ◽  
Joshua L. Bonkowsky

Innovative therapeutics are transforming care of children with previously untreatable neurological disorders. However, there are challenges in the use of new therapies: the medicine may not be effective in all patients, administration may not be tolerated, and matching therapy choice to patient is complex. Finally, costs are high, which imposes financial burdens on insurance companies, families, and the health-care system. Our objective was to address challenges for clinical implementation of the new therapeutics. We sought to develop a process that would be personalized for patient and disease, encourage appropriate use of a therapeutic agent while mitigating pressure on a clinician to prescribe the therapy in all instances, and assist third-party payers in approving therapeutic use based on safety and efficacy. We report our creation of a Neurology Therapeutics Committee for pediatric patients. We review the committee’s mechanisms, describe its use and report outcomes, and suggest the Neurology Therapeutics Committee’s broader applicability.


2018 ◽  
Vol 38 (5) ◽  
pp. 26-31 ◽  
Author(s):  
Calvin Tucker ◽  
Lyn Tucker ◽  
Kyle Brown

Intranasal drug administration is a less invasive method of drug delivery that is easily accessible for adult and pediatric patients. Medications administered by the intranasal route have efficacy comparable to intravenous administration and typically have superior efficacy to subcutaneous or intramuscular routes. The intranasal route is beneficial in emergent situations when the intravenous route is not available. The intranasal route is safe and effective in various indications, and therapeutic systemic concentrations of medication can be attained via this route. As the evidence for and comfort with intranasal administration continue to grow, guidance on correct technique, medications, and dosing is vital for appropriate use. This article reviews the process and practices of appropriate intranasal medication administration.


2008 ◽  
Vol 34 (7) ◽  
pp. 1274-1280 ◽  
Author(s):  
Nameet Jerath ◽  
Helena Frndova ◽  
Brian W. McCrindle ◽  
Rebecca Gurofsky ◽  
Tilman Humpl

2013 ◽  
Vol 26 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Ritu Sachdeva ◽  
Elizabeth A. Frazier ◽  
Robert D.B. Jaquiss ◽  
Michiaki Imamura ◽  
Christopher J. Swearingen ◽  
...  

2005 ◽  
Vol 26 (6) ◽  
pp. 745-750 ◽  
Author(s):  
C.-D. Liang ◽  
S.-F. Ko ◽  
C.-F. Huang ◽  
S.-C. Huang

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