Comparative Visualization of Tracer Uptake in In Vivo Small Animal PET/CT Imaging of the Carotid Arteries

2013 ◽  
Vol 32 (3pt2) ◽  
pp. 241-250 ◽  
Author(s):  
S. Diepenbrock ◽  
S. Hermann ◽  
M. Schäfers ◽  
M. Kuhlmann ◽  
K. Hinrichs
Keyword(s):  
Carotid Arteries ◽  
Small Animal ◽  
Tracer Uptake ◽  
Ct Imaging ◽  
Small Animal Pet ◽  
Comparative Visualization ◽  
Animal Pet ◽  
Pet Ct

Implementation of 89Zr production and in vivo imaging of B-cells in mice with 89Zr-labeled anti-B-cell antibodies by small animal PET/CT

2011 ◽  
Vol 69 (6) ◽  
pp. 852-857 ◽  
Author(s):  
Martin Walther ◽  
Peter Gebhardt ◽  
Philipp Grosse-Gehling ◽  
Lydia Würbach ◽  
Ingo Irmler ◽  
...  
Keyword(s):  
B Cells ◽  
B Cell ◽  
In Vivo Imaging ◽  
Small Animal ◽  
Small Animal Pet ◽  
Animal Pet ◽  
Pet Ct

scholarly journals Prototype Small-Animal PET-CT Imaging System for Image-Guided Radiation Therapy

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 143207-143216
Author(s):  
Ekaterina Mikhaylova ◽  
Jamison Brooks ◽  
Darren M. Zuro ◽  
Farouk Nouizi ◽  
Maciej Kujawski ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Imaging System ◽  
Small Animal ◽  
Ct Imaging ◽  
Small Animal Pet ◽  
Animal Pet ◽  
Image Guided Radiation Therapy ◽  
Image Guided ◽  
Pet Ct

scholarly journals Small-Animal PET/CT Imaging of Local and Systemic Immune Response Using 64Cu-αCD11b

2019 ◽  
Vol 60 (9) ◽  
pp. 1317-1324 ◽  
Author(s):  
Qizhen Cao ◽  
Qian Huang ◽  
Chandra Mohan ◽  
Chun Li
Keyword(s):  
Immune Response ◽  
Small Animal ◽  
Ct Imaging ◽  
Small Animal Pet ◽  
Systemic Immune Response ◽  
Animal Pet ◽  
Pet Ct

scholarly journals In Vivo Small-Animal PET/CT of EphB4 Receptors Using 64Cu-Labeled Peptide

2011 ◽  
Vol 52 (2) ◽  
pp. 241-248 ◽  
Author(s):  
C. Xiong ◽  
M. Huang ◽  
R. Zhang ◽  
S. Song ◽  
W. Lu ◽  
...  
Keyword(s):  
Small Animal ◽  
Small Animal Pet ◽  
Animal Pet ◽  
Pet Ct

scholarly journals High Throughput PET/CT Imaging Using a Multiple Mouse Imaging System

2019 ◽  
Author(s):  
Hannah E. Greenwood ◽  
Zoltan Nyitrai ◽  
Gabor Mocsai ◽  
Sandor Hobor ◽  
Timothy H. Witney
Keyword(s):  
Image Quality ◽  
Fdg Pet ◽  
Imaging System ◽  
Small Animal ◽  
Ct Imaging ◽  
Small Animal Pet ◽  
Pet Ct ◽  
Fdg Pet Ct ◽  
The Cost

AbstractA considerable limitation of current small animal positron emission tomography/computed tomography (PET/CT) imaging is the low throughput of image acquisitions. Subsequently, to design sufficiently-powered studies, high costs accumulate. Together with Mediso Medical Imaging Systems, a four-bed mouse ‘hotel’ was developed to simultaneously image up to four mice, thereby reducing the cost and maximising radiotracer usage when compared to scans performed with a single mouse bed.MethodsFor physiological evaluation of the four-bed mouse hotel, temperature and anaesthesia were tested for uniformity, followed by [18F]fluorodeoxyglucose (FDG) PET/CT imaging of ‘mini’ image quality (IQ) phantoms specifically designed to fit the new imaging system. Post-reconstruction, National Electrical Manufacturers Association (NEMA) NU-4 tests examined uniformity, recovery coefficients (RCs) and spill-over ratios (SORs). To evaluate the bed under standard in vivo imaging conditions, four mice were simultaneously scanned by dynamic [18F]FDG PET/CT over 60 minutes using the four-bed mouse hotel, with quantified images compared to those acquired using a single mouse bed.ResultsThe bed maintained a constant temperature of 36.8°C ± 0.4°C (n = 4), with anaesthesia distributed evenly to each nose cone (2.9 ± 0.1 L/min, n = 4). The NEMA tests performed on reconstructed mini IQ phantom images acquired using the four-bed mouse hotel revealed values within the tolerable limits for uniformity, RC values in >2mm rods, and SORs in the non-radioactive water- and air-filled chambers. There was low variability in radiotracer uptake in all major organs of mice scanned using the four-animal bed versus those imaged using a single bed imaging platform.ConclusionAnalysis of images acquired using the four-bed mouse hotel confirmed its utility to increase the throughput of small animal PET imaging without considerable loss of image quality and quantitative precision. In comparison to a single mouse bed, the cost and time associated with each scan were substantially reduced.

Validation of a Novel CHX-A‘ ‘ Derivative Suitable for Peptide Conjugation:  Small Animal PET/CT Imaging Using Yttrium-86-CHX-A‘ ‘-Octreotide

2006 ◽  
Vol 49 (14) ◽  
pp. 4297-4304 ◽  
Author(s):  
Thomas Clifford ◽  
C. Andrew Boswell ◽  
Gráinne B. Biddlecombe ◽  
Jason S. Lewis ◽  
Martin W. Brechbiel
Keyword(s):  
Small Animal ◽  
Ct Imaging ◽  
Small Animal Pet ◽  
Animal Pet ◽  
Pet Ct ◽  
Peptide Conjugation

Multimodal evaluation of xenograft tumors in mice with an in-vivo stereo imaging system and small-animal PET/CT

2013 ◽  
Vol 23 (5) ◽  
pp. 349-359 ◽  
Author(s):  
Onseok Lee ◽  
Gunwoo Lee ◽  
Mingi Kim ◽  
Seok-ki Kim ◽  
Yoosang Baek ◽  
...  
Keyword(s):  
Imaging System ◽  
Small Animal ◽  
Small Animal Pet ◽  
Stereo Imaging ◽  
Animal Pet ◽  
Pet Ct

scholarly journals In Vivo Evaluation and Small-Animal PET/CT of a Prostate Cancer Mouse Model Using 64Cu Bombesin Analogs: Side-by-Side Comparison of the CB-TE2A and DOTA Chelation Systems

2007 ◽  
Vol 48 (8) ◽  
pp. 1327-1337 ◽  
Author(s):  
J. C. Garrison ◽  
T. L. Rold ◽  
G. L. Sieckman ◽  
S. D. Figueroa ◽  
W. A. Volkert ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Mouse Model ◽  
Small Animal ◽  
Small Animal Pet ◽  
In Vivo Evaluation ◽  
Animal Pet ◽  
Pet Ct
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