Novel homozygous variations in PLCZ1 lead to poor or failed fertilization characterized by abnormal localization patterns of PLCζ in sperm

2019 ◽  
Vol 97 (2) ◽  
pp. 347-351 ◽  
Author(s):  
Jing Dai ◽  
Can Dai ◽  
Jing Guo ◽  
Wei Zheng ◽  
Tianlei Zhang ◽  
...  
Keyword(s):  
Failed Fertilization

scholarly journals Novel mutations in the PLCZ1 gene associated with human low or failed fertilization

2020 ◽  
Vol 8 (10) ◽  
Author(s):  
Ping Yuan ◽  
Lingyan Zheng ◽  
Hao Liang ◽  
Qiyuan Lin ◽  
Songbang Ou ◽  
...  
Keyword(s):  
Novel Mutations ◽  
Failed Fertilization

Experience with assisted fertilization in severe male factor infertility and unexplained failed fertilization in vitro

1994 ◽  
Vol 9 (4) ◽  
pp. 680-683 ◽  
Author(s):  
C.J. Redgment ◽  
D. Yang ◽  
M. Tsirigotis ◽  
N. Yazdani ◽  
T. AI Shawaf ◽  
...  
Keyword(s):  
Fertilization In Vitro ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Failed Fertilization ◽  
Assisted Fertilization

Assisted fertilization by subzonal insemination and intracytoplasmic sperm injection

1994 ◽  
Vol 6 (1) ◽  
pp. 85 ◽  
Author(s):  
Steirteghem A Van ◽  
J Liu ◽  
H Joris ◽  
Z Nagy ◽  
C Staessen ◽  
...  
Keyword(s):  
Intracytoplasmic Sperm Injection ◽  
Congenital Malformations ◽  
Subsequent Development ◽  
Fertilization Rate ◽  
Subzonal Insemination ◽  
Failed Fertilization ◽  
Assisted Fertilization ◽  
Normal Fertilization

The results of 600 consecutive treatment cycles of subzonal insemination (SUZI) and intracytoplasmic sperm injection (ICSI) are described in couples with failed fertilization after standard IVF or insufficient spermatozoa in the ejaculate for IVF. More oocytes were damaged by ICSI (16.3%) than by SUZI (8.5%) and the normal fertilization rate was substantially higher after ICSI (49.1% v. 16.6%). Subsequent development of two-pronuclear oocytes in vitro was 80% after SUZI and 73.9% after ICSI. Significantly more triple embryo replacements were carried out after ICSI than after SUZI. Embryo transfers were possible in 421 of the 600 cycles. There were 63 pregnancies after ICSI (215 transfers) and 23 after SUZI (156 transfers); 10 additional pregnancies were achieved after 50 transfers of a mixture of SUZI and ICSI embryos. The results of fetal karyotypes and follow-up of the children do not indicate an increase in congenital malformations.

Total failed fertilization in IVF: current etiologies and predictors

2008 ◽  
Vol 90 ◽  
pp. S338-S339
Author(s):  
J.F. McLaren ◽  
T.A. Molinaro ◽  
S.L. Croly ◽  
C. Coutifaris ◽  
A. Dokras
Keyword(s):  
Failed Fertilization

Failed fertilization: is it predictable?

2003 ◽  
Vol 15 (3) ◽  
pp. 211-218
Author(s):  
Neal G. Mahutte ◽  
Aydin Arici
Keyword(s):  
Failed Fertilization
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